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250. When You Should Worry About LDL Cholesterol with Mike Fave

Paul Saladino MD podcast

CHAPTER

Insights into Blood Markers and Cardiovascular Risk

The chapter explores various blood markers such as high sensitivity CRP, homocysteine, and insulin that offer insights into cardiovascular risk factors, metabolic function, and vasculature health. It challenges the traditional belief that LDL cholesterol alone determines cardiovascular risk, emphasizing the importance of considering additional markers like CAC scores and fasting insulin to comprehensively assess cardiovascular health. The conversation discusses studies on individuals with high LDL levels but low plaque burdens, questioning the linear relationship between LDL levels and plaque formation in conditions like familial hypercholesterolemia.

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