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16min chapter
250. When You Should Worry About LDL Cholesterol with Mike Fave
Paul Saladino MD podcast
Impact of PCSK9 Genetic Variants on Diabetes Risk and Lipid-Lowering Interventions
The chapter explores how PCSK9 genetic variants can influence LDL levels and the risk of type 2 diabetes, shedding light on adverse metabolic consequences. It discusses the implications of HMG-CoA reductase polymorphisms on diabetes risk and the potential consequences of lipid-lowering interventions. The conversation underscores the importance of considering various health factors like all-cause mortality, cancer risks, infections, and drug effects when assessing the effects of lowering cholesterol levels on overall health outcomes.
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