Spermidine's Role in Cellular Health - Dr. Elizabeth Yurth : 1160
May 16, 2024
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Dr. Elizabeth Yurth, an expert in orthopedics and regenerative medicine, discusses the benefits of spermidine in promoting cellular health, autophagy, and kidney health. She explains how spermidine can be combined with NAD for anti-aging effects. Practical tips are shared on integrating these supplements into daily routines for sustained energy and vitality as you age.
Spermidine promotes autophagy for better cellular health and youthfulness.
Spermidine supports kidney health and anti-aging effects when combined with NAD.
Integrating spermidine and NAD into daily routine enhances energy, cellular function, and longevity.
Deep dives
Starting the Biohacking Movement for Longevity and Energy Enhancement
Dave Asprey shares frustrations that led to the biohacking movement, focusing on longevity, energy, and attractiveness throughout life. Beginning biohacking at a young age promises benefits in academic success, career growth, well-being, and relationship quality.
Benefits of Fasting and the Potency of Spermidine
Dave Asprey delves into the benefits of fasting and the misperceptions surrounding daily fasting. Spermidine, a postbiotic found in foods and supplements, mimics fasting effects, promoting autophagy and enhancing longevity. Dr. Elizabeth Ureth shares insights on spermidine's role and impact on cellular health.
Tissue Transglutaminase and Spermidine's Role in Inhibition
The discussion shifts to tissue transglutaminase inhibition and its relevance in celiac disease, gluten sensitivity, and broader health issues. Spermidine's ability to inhibit tissue transglutaminase and induce autophagy highlights its potential in mitigating immune responses and promoting overall health.
Hair Growth, Inflammatory Reduction, and Endothelial Function with Spermidine
The conversation extends to spermidine's impact on hair growth, inflammation reduction, and endothelial function. Studies illustrate spermidine's role in promoting hair growth, lowering inflammatory markers like NLP3 inflammasome and interleukin-1 beta, and enhancing endothelial function to benefit cardiovascular health and kidney function.
Optimizing Kidney Function and Longevity
Not all traditional measures of kidney function may be accurate for individuals who consume high protein diets or take creatine supplements, as these factors can impact creatinine levels and skew glomerular filtration rates. Using alternative assessments like cystatin C can provide a more reliable indicator of kidney health, especially for individuals with specific dietary habits or supplement regimens. Ensuring kidney health is crucial for overall well-being and longevity, with compounds like spermidine and clotho showing promising results in supporting kidney function and extending lifespan.
Balancing Supplement Protocols for Longevity
Balancing supplement intake for longevity involves strategic cycling and prioritization to optimize health outcomes while managing costs and practicality. Incorporating a diverse range of compounds like spermidine, NAD precursors, and specialized formulations can target multiple pathways associated with aging and disease prevention. Supplement cycling allows for tailored approaches based on individual needs and budgets, aiming to maximize benefits while avoiding unnecessary risks associated with excessive or overlapping supplementation.
In this episode of "The Human Upgrade," you will learn from Dr. Elizabeth Yurth, an expert in orthopedics, cellular medicine, and regenerative medicine, about the significant health benefits of spermidine, a supplement that enhances longevity and supports robust health. Dr. Yurth discusses the crucial role of spermidine in promoting autophagy, the body's natural process for clearing out damaged cells, which can lead to better cellular health and a more youthful body. She also dives into how spermidine supports kidney health and how it can be combined with NAD to maximize anti-aging effects. Additionally, you will discover practical tips from Dr. Yurth on integrating these powerful supplements into your daily routine to maintain energy levels, improve cellular function, and sustain a vigorous and healthy life as you age. This episode provides deep insights into making informed choices about supplements that support long-term health goals.
Timestamp Highlights:
(00:00:01) Introduction: Background and the inception of biohacking.
(00:01:08) Early biological management and its long-term benefits.
(00:01:57) Misconceptions about fasting and the role of spermidine.
(00:02:43) Dr. Uth's journey from orthopedics to longevity medicine.
(00:06:17) Deep dive into spermidine: benefits, sources, and mechanisms.
(00:10:43) Dietary sources of spermidine and its importance in diet.
(00:16:02) Spermidine as a crucial nutrient for autophagy and its mechanisms.
(00:19:13) Comparing spermidine with fasting and rapamycin for longevity.
(00:22:25) Practical dosing advice for spermidine.
(00:33:24) The optimal timing and method of spermidine supplementation.
(00:41:58) Spermidine's effects on hair growth and its potential as a topical application.
(01:07:17) Discussion on the future of longevity treatments and gene therapy.
Sponsors:
spermidineLIFE | Go to spermidineLIFE.us and use code Asprey25 at checkout for 25% off your order.
EnVy | Go to envypillow.com and use code DAVE at checkout for an exclusive discount