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Dr. Kate Shanahan introduces the concept of the 'Hateful Eight,' which refers to eight specific seed oils that she considers detrimental to human health. These oils, including corn, canola, cottonseed, soy, sunflower, safflower, rice bran, and grapeseed, are recognized for their high levels of polyunsaturated fats and the fact that they require extensive refining to be made edible. This refining process strips these oils of any nutritional value and transforms them into harmful substances that can cause oxidative stress in the body. The discussion emphasizes that if the term 'Hateful Eight' isn't used, misconceptions about the toxicity of different oils can arise, indicating a lack of understanding in the conversation about seed oils.