The mindbodygreen Podcast

Dr. Saranya Wyles, a leading dermatologist and regenerative medicine scientist at the Mayo Clinic, discusses the skin's role as a visible indicator of internal aging. She explains the five pillars of skin longevity: sleep, diet, exercise, stress management, and topicals. Wyles emphasizes the importance of a Mediterranean diet, effective sunscreen, and innovative treatments like lasers to rejuvenate skin. She even connects skin health to cognitive function, revealing fascinating insights into how cellular aging can impact the mind.

Discover a fascinating tale of 1980s scientists who, while trying to induce heart disease in rabbits, stumbled upon a surprising finding: the power of emotional connection. One group of rabbits received extra love and care, resulting in healthier hearts. Explore how the way we eat—who we eat with and our emotional state—can significantly impact our cardiovascular health. The discussion dives into the science of eating in a relaxed environment and the idea that love and presence can protect our hearts, reshaping our approach to nutrition.

Jaime Seeman, M.D., a board-certified obstetrician-gynecologist and fitness expert, shares powerful insights on women's health and muscle building. She emphasizes the importance of resistance training over excessive cardio and discusses effective fasting practices. Dr. Seeman highlights how nutrition needs evolve through the decades, particularly postpartum challenges and the significance of protein intake as women age. She also touches on hormone replacement therapy and the benefits of creatine for both muscle and brain health across the lifespan.

Rocío Salas-Whalen, M.D., a board-certified endocrinologist and an expert in GLP-1 therapies, dives into the crucial link between muscle mass and metabolism. She emphasizes that muscle loss poses greater health risks than excess fat. Rocío discusses the benefits of GLP-1s, when they're appropriate, and highlights the importance of protein and strength training in preserving muscle on these medications. She also addresses common misconceptions and the role of mindset in achieving long-term health goals, particularly in the context of obesity and lifestyle changes.

“There are hundreds, maybe thousands, of drug repurposing opportunities just waiting to be uncovered,” explains David Fajgenbaum, M.D.  David Fajgenbaum, M.D., physician-scientist, bestselling author of Chasing My Cure, co-founder of Every Cure, and leader in the global push for drug repurposing, joins us today to explain why the cures of tomorrow may already be on pharmacy shelves today—and how his team is racing to uncover them. - From college athlete to ICU (~3:15) - Finding a cure (~7:20) - Hope needs to drive action (~9:45) - Repurposing drugs (~11:10) - Use cases of generic drugs (~13:30) - Lithium for bipolar & Alzheimer’s (~16:00) - Lidocaine & breast cancer (~17:25) - GLP-1 for longevity benefits (~19:20) - Increasing awareness in the healthcare system (~20:10) - The 3 main hurdles for repurposing drugs (~22:00) - Opportunities in the space (~23:10) - 14 advanced repurpose treatments (~28:00) - The power of AI (~32:50) - Using AI for personalized medicine (~34:30) - AI for treatment options (~37:45) - Common drugs with big potential (~41:00) - The future of healthcare & drug discovery (~44:50) - How you can help (~49:30) Referenced in the episode:  - Follow Fajgenbaum on Instagram (@dfajgenbaum)  - Check out his website (https://davidfajgenbaum.com/)  - Listen to his previous episode on the mbg podcast  (https://podcasts.apple.com/us/podcast/life-lessons-from-a-doctor-who-almost-died-from/id1246494475?i=1000470061486) - Pick up his book, Chasing My Cure (https://www.amazon.com/Chasing-My-Cure-Doctors-Action/dp/1524799637/)  - Listen to his TED Talk (https://www.youtube.com/watch?v=sb34MfJjurc)   - Learn more about Every Cure (https://everycure.org/) We hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Ana Kausel, a board-certified endocrinologist specializing in women's health, delves into the secrets of metabolic strength and nutrition. She shares her personal journey of muscle gain, emphasizing the necessity of carbohydrates for effective strength training. Ana discusses the personalized approach to GLP-1 dosages for weight management and the importance of balancing protein and fat. She highlights the complexities of female hormone testing and offers insights on dietary choices for optimal health, advocating for a Mediterranean-style eating philosophy.

Shannon Ritchey, a Doctor of Physical Therapy and founder of Evlo Fitness, discusses smarter training techniques for building muscle without burnout. She emphasizes that muscle is built during recovery, not just workouts. Shannon highlights the downsides of group fitness classes, the importance of training to failure, and the benefits of intentional strength sessions. She also offers insights on efficient weekly workout structures, nutrition tracking, and postpartum muscle rebuilding, all while advocating for a balanced approach to fitness that promotes long-term health.

In this conversation with Daniel Amen, M.D., a double board-certified psychiatrist and bestselling author, listeners explore the profound link between brain health and pain. Amen explains how chronic pain is fundamentally processed in the brain and identifies what constitutes an unhealthy brain. He offers insights into emotional red flags, the 'Doom Loop' impacting pain management, and shares practical tips for strengthening the frontal lobes. With personal anecdotes and expert recommendations, he emphasizes the importance of understanding triggers and managing emotions for overall well-being.

In this engaging discussion, Dr. Robin Rose, a double board-certified gastroenterologist and CEO of Terrain Health, sheds light on the hidden impacts of COVID-19. She explains how lingering spike proteins can lead to issues like Long COVID, neuroinflammation, and gut dysbiosis. Listeners learn about crucial biomarkers for identifying Long COVID and practical detox methods. Dr. Rose emphasizes the connection between COVID and neurodegenerative diseases, urging the importance of addressing these effects for a healthier future.

Peter Attia, M.D., a physician and longevity expert, dives into the critical role of VO2 max as a lifespan predictor. He explains how to enhance VO2 max through interval training and emphasizes the limit of exercise, even comparing it to pharmaceuticals. Attia shares insights on cardiovascular markers like ApoB and Lp(a) and the evolving views on GLP-1s for neuroprotection. With a focus on practicality, he highlights the underestimated power of structured exercise while adding his humorous takes on life and fitness.