The mindbodygreen Podcast 569: How to improve mitochondrial & muscle health | Anurag Singh, M.D., Ph.D.
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Dec 1, 2024 Anurag Singh, M.D., Ph.D., Chief Medical Officer at Timeline Nutrition and a mitochondrial health expert, shares insights on the vital role mitochondria play in overall health. He discusses how lifestyle factors, like exercise and diet, impact mitochondrial function. The conversation highlights Urolithin A, its benefits for muscle strength and aging, and the significance of autophagy in cellular health. Singh also emphasizes combating sarcopenia through nutrition and resistance training, alongside innovative ways to assess mitochondrial health for enhanced well-being.
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Mitochondrial Dysfunction and Aging
- Mitochondrial dysfunction, a hallmark of aging, occurs as mitochondria accumulate damage and cannot be replaced efficiently.
- This leads to decreased energy reserves in metabolically active cells like muscle, brain, and heart cells.
Lifestyle's Impact on Mitochondrial Health
- Lifestyle factors like decreased physical activity, poor diet, stress, and lack of sleep contribute to mitochondrial decline.
- A study comparing active and sedentary older adults revealed significant differences in mitochondrial health.
Exercise and Fasting for Mitochondrial Health
- Exercise 30 minutes, three times a week, and practice intermittent fasting to support mitochondrial health.
- Both activities induce autophagy, a self-cleaning process that removes damaged cells and mitochondria.