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The mindbodygreen Podcast

569: How to improve mitochondrial & muscle health | Anurag Singh, M.D., Ph.D.

Dec 1, 2024
Anurag Singh, M.D., Ph.D., Chief Medical Officer at Timeline Nutrition and a mitochondrial health expert, shares insights on the vital role mitochondria play in overall health. He discusses how lifestyle factors, like exercise and diet, impact mitochondrial function. The conversation highlights Urolithin A, its benefits for muscle strength and aging, and the significance of autophagy in cellular health. Singh also emphasizes combating sarcopenia through nutrition and resistance training, alongside innovative ways to assess mitochondrial health for enhanced well-being.
42:46

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Quick takeaways

  • Mitochondrial dysfunction significantly impacts aging and overall health, underscoring the importance of maintaining mitochondrial vitality through proactive lifestyle choices.
  • Urolithin A is a promising postbiotic that enhances mitochondrial function and muscle health, highlighting the need for dietary interventions or supplementation.

Deep dives

Understanding Mitochondrial Dysfunction

Mitochondrial dysfunction is identified as a central factor in aging, described through the analogy of a phone battery losing charge over time. As people age, mitochondria, the energy-producing organelles in cells, become stressed and damaged, leading to a decline in overall energy reserves. The accumulation of damaged mitochondria particularly affects metabolically active tissues like muscles, brain, and heart, which require substantial energy to function effectively. Lifestyle factors, including physical inactivity, poor diet, and stress, contribute significantly to the deterioration of mitochondrial health, emphasizing the need for proactive approaches to maintain cellular vitality.

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