
Brains and Gains with Dr. David Maconi
On the Brains and Gains podcast, Dr. David Maconi discusses all things exercise science, nutrition, health, and personal development. Every week, Dr. Maconi invites health experts and thought leaders to share their expertise. Each episode ends with a charity donation to the charity of the guest's choice.
Latest episodes

4 snips
Sep 29, 2024 • 1h 44min
Alex Leonidas - Energy Flux, Calisthenics, Best Curls, Vegan Gains
In this episode, health and fitness expert Alex Leonidas dives into the intriguing concept of G-Flux, explaining how energy balance influences performance. He discusses the challenges of maintaining strength while cutting and shares valuable tips for calisthenics. Alex also explores the nuances of a vegan diet, shedding light on common mistakes and the importance of balanced nutrition. He critiques partial reps in weightlifting, advocating for full range motion to maximize results, and revisits the evolution of bicep training, combining science with personal anecdotes.

Sep 20, 2024 • 55min
Nicolas Verhoeven (Part 2) - Rancid Fish Oil, Xylitol Dangers, Medical Innovation
0:00- Intro 0:45- Fish oil and oxidation 18:50- Xylitol and Erythritol 28:00- Controlling for multiple variables 34:30- Rhodiola and stress 40:10- The future of medical innovation

Sep 13, 2024 • 53min
Nicolas Verhoeven (Part 1) - Saturated Fat, LDL and ApoB, Statins and PCSK9 Inhibitors
0:00- Intro 0:30- PhD process 8:00- Repetitiveness in expertise 14:40- Saturated fat, LDL, and ApoB 41:00- Statins, PCSK9 inhibitors 47:00- Human equivalent doses

Aug 31, 2024 • 1h 11min
Vigorous Steve - Finasteride, Fertility, Health Markers
0:00- Intro 1:00- Taking gear for events 4:00- Having enhanced guests on the podcast 10:00- Testing health markers while on a cycle 15:40- Finasteride 37:20- Fertility struggles 46:00- Adoption 51:30- Leo and Longevity update 56:30- the future of medicine

Aug 23, 2024 • 1h 6min
Brian DeCosta - Elite Genetics, High Volumes, What Motivates Top Athletes
0:00- Intro 0:30- Charity donation 1:30- Background on Brian 5:00- Genetics 10:30- What is truly impressive? 13:30- Is it harder to draw motivation as you become more successful? 18:00- Training with Mike Israetel and Jared Feather 19:30- High training volumes 21:30- Deloading and periodizing 25:00- Recovery and supplements 31:30- Social media and phone addiction 37:30- The psychological benefits of exercising regularly 41:30- Thinking about the aging bodybuilder 43:00- Physical endeavors outside of bodybuilding 49:00- Strength comparisons relative to bodyweight 53:00- Dealing with criticism from others 1:01:00- Coaching as a long-term career 1:05:00- Where to find Brian

Aug 10, 2024 • 1h 42min
Q&A 14 (Ft. Abel Csabai) - Wasting Newbie Gains, Importance of Carbs, Extending Intensity Sets
In this episode, fitness expert Abel Csabai shares his insights on effective training techniques and nutrition. He discusses the nuances of myo-reps and rest-pause sets, addressing how to push your limits safely. Abel emphasizes the critical role of carbohydrates in muscle growth and explores the potential for wasting newbie gains if training isn't optimized. He also touches on the importance of dental health and how fitness influences romantic attraction, revealing that personality often outweighs physical appearance.

Jul 26, 2024 • 1h 43min
Eric Helms + Steve Hall - Leaner Gains, Individual Fatigue, Supersetting
0:00- Intro 1:00- Taking gains from other muscle groups 7:00- Will untrained muscles hold back maximal growth of other muscles? 14:00- How are we tracking workouts? 18:00- Boostcamp 19:00- Future competition plans 26:00- Should anyone be bulking up for gains? 33:00- Dedicating oneself to purely bodybuilding 37:00- Rest pause vs drop sets vs straight sets 50:00- Fatigue drop offs set to set59:00- Are Eric and Steve doing cardio?1:02:00- Supersetting at the gym1:09:00- VO2 Max1:10:00- Getting a deep stretch on back exercises1:19:00- Bathroom frequency while bulking vs cutting \1:27:00- Finasteride1:35:00- Wrapping up with future plans

Jul 13, 2024 • 1h 16min
Pete Rubish - Regaining Muscle Drug Free, Ultra Running, Health Above All
0:00- Intro 2:00- Pete’s strongest lifts 5:30- Maintaining vs losing steroid gains 10:00- Total testosterone levels on TRT 17:00- What made Pete want to do ultra running 19:00- Stopping lifting after gear use 24:00- Mistakes made with 100 mile run 47:15- Age range of ultra runners 50:00- Did Pete actually maintain muscle from previous PED usage? 51:00- Kidney stone issues 57:00- Vitamin D supplementation 1:00:30- Pete’s imaging and testing for health 1:15:00- Wrapping up and where to find Pete

Jul 6, 2024 • 1h 6min
Basement Bodybuilding - Breaking Arm Plateaus, Backing Off Leg Training, Home Gyms
0:00- Intro 0:30- Hitting 18in arms 10:45- Progressive overload 12:20- What was done specifically to get to 18in arms 26:00- Exercise and rep selection 36:30- Should you train legs as hard as upper body? 46:00- Home gymsBasement Bodybuilding Channel: / @basementbodybuilding Basement Bodybuilding Instagram: / basement.bodybuilding Website and Coaching: https://brainsandgainspodcast.com/Instagram: / dave_maconi / @brainsandgainspodcast -For those looking to support the channel and our donations to various charities, please consider the above link to become a member and have the opportunity to appear on the channel!Jacked Up home gym equipment: https://jackedupbrands.com/pages/_go_...

May 18, 2024 • 1h 28min
Abel Q&A 13 (Ft. Abel Csabai) - Bulking on Fewer Meals, Exercise Frequency, Ab Progression
0:00- Intro 3:00- Where has Abel been? 12:00- How to lose weight 13:00- Is it really possible to bulk on 3 meals per day? 23:10- Is it better to have an A-B exercise selection or hit the same exercises every time? 35:20- Ab training and progressionAbel's channel for part 2: • Stubborn pecs, rest-pause for unilate... Website and Coaching: https://brainsandgainspodcast.com/Instagram: / dave_maconi / @brainsandgainspodcast -For those looking to support the channel and our donations to various charities, please consider the above link to become a member and have the opportunity to appear on the channel!Jacked Up home gym equipment: https://jackedupbrands.com/pages/_go_...BULK SUPPLEMENTS AFFILIATE LINK: https://glnk.io/63qn/dave-maconiDiscount code: DAVE5OFF
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