

The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™.You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable. You’ll learn from experts around the world who elevate what it means to be human.Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward.Join The Human Upgrade™ with Dave Asprey on this next evolution to upgrade your mind, body and life.
Episodes
Mentioned books

97 snips
Jun 10, 2025 • 1h 6min
Should You Eat Dirt? The “Healthy” Foods Destroying Your Gut – Dr. Josh Axe : 1289
Dr. Josh Axe, a pioneer in functional medicine and co-founder of Ancient Nutrition, sheds light on the surprising dangers of 'healthy' foods for your gut and hormones. He discusses the decline of soil nutrients, the pitfalls of monocropping, and how regenerative farming can rejuvenate both health and the planet. The conversation dives into the impact of environmental factors on hormonal balance, challenges posed by modern diets, and introduces natural alternatives for hormone optimization. Prepare for a fascinating exploration of nutrition that fuses ancient wisdom with cutting-edge science!

46 snips
Jun 5, 2025 • 53min
How 5G Affects Brainwaves (and the New Science to Fix It) : 1288
Philipp Samor von Holtzendorff-Fehling, founder of Quantum Upgrade and former T-Mobile VP, dives into the effects of 5G on brainwaves and cognitive function. He discusses groundbreaking EEG research showing how EMF exposure disrupts brain activity. The conversation covers innovative techniques for biohacking and EMF mitigation, emphasizing emerging tools that even skeptics are recognizing. Listeners learn about the benefits for athletes and the potential for enhanced brain health and resilience against high-EMF environments, making this a must-listen for anyone seeking to optimize their mental performance.

100 snips
Jun 3, 2025 • 1h 23min
Mark Sisson: The Japanese Walking Hack That Outperforms 10,000 Steps A Day : 1287
Mark Sisson, bestselling author and primal health pioneer, shares insights on innovative walking techniques that can outperform the traditional 10,000 steps a day. He highlights the benefits of the Japanese walking interval method for longevity and fat burning. Sisson emphasizes the critical connection between foot health and overall well-being, advocating for barefoot shoes and minimal footwear. He reveals how effective movement and training for just 20 minutes a week can enhance performance without compromising mitochondrial health, urging listeners to embrace smarter exercise strategies.

38 snips
May 29, 2025 • 1h 15min
60 Days Alone in Antarctica: Amputation, Frostbite, and Lessons from Extreme Suffering | Akshay Nanavati : 1286
In this engaging conversation, elite adventurer Akshay Nanavati, a Marine Corps veteran and founder of Fearvana, shares his gripping experience of surviving 60 days alone in Antarctica. He reveals how he used extreme suffering as a catalyst for spiritual awakening and peak performance. The discussion dives into the neuroscience of pain, the paradox of joy found in discomfort, and the transformative power of solitude. Akshay's insights on navigating trauma, resilience, and the duality of life's challenges offer profound wisdom, encouraging listeners to embrace both fear and growth.

120 snips
May 27, 2025 • 59min
10-Second Breath Hack to Reset Your Body & Mind | Aaron Alexander : 1285
Aaron Alexander, a human performance coach and creator of The Align Method, shares powerful insights into the art of breathwork. He explains how a simple breathing technique can swiftly reset your nervous system and regulate stress. Alexander highlights the crucial link between jaw alignment, posture, and overall health, revealing how these factors can impact emotional well-being. He also emphasizes the importance of mouth taping for improved sleep and explores the body-mind connection with practical tips for optimizing vitality and personal growth.

47 snips
May 22, 2025 • 59min
Ayurveda Meets Biohacking: 5000-Year-Old Medicine Secrets for Modern Stress | Mona Sharma : 1284
Join Mona Sharma, an Ayurvedic practitioner and wellness expert who blends Vedic traditions with modern science. She shares fascinating insights on ancient health protocols to combat stress and enhance performance. Discover how breathwork and detoxification can rewire the nervous system and promote emotional resilience. Mona discusses the significance of managing chronic stress through self-awareness and practical techniques. Learn how to incorporate Ayurveda’s wisdom into daily routines for optimal health in today’s fast-paced world.

66 snips
May 20, 2025 • 1h 4min
The Biohacker’s Guide to CIA Mind Control & Brainwashing : 1283
Rebecca Lemov, a Harvard historian and expert on psychological manipulation, delves into the insidious nature of mind control. She reveals how techniques from MK Ultra evolved into modern forms of influence through social media and technology. The conversation explores the ethics of autonomy in an age of pervasive psychological tactics. Lemov also discusses the historical ties to psychedelics and the unsettling legacy of government experimentation. Listeners gain insights on protecting their thoughts and emotional well-being from external manipulations.

102 snips
May 16, 2025 • 1h 27min
Military Tech Goes Public: Think 30% Faster with This Brain Hack | Geoffrey Woo : 1282
In this engaging discussion, Geoffrey Woo, a Stanford-trained computer scientist and the founder of Ketone-IQ, dives into the world of brain optimization. He highlights how ketones, used by elite forces, enhance focus and improve reaction times by up to 30%. The conversation delves into the benefits of ketones over glucose for cognitive health and their potential in biohacking for athletes and entrepreneurs. Woo also shares insights on innovation in ketone production and challenges faced while securing military contracts, emphasizing resilience in the entrepreneurial journey.

30 snips
May 15, 2025 • 49min
The Anti-Aging Chamber That Rewinds Your Biological Clock|Dr. Jason Sonners : 1281
Dr. Jason Sonners, a leading expert in hyperbaric oxygen therapy, shares insights on how controlled oxygen can rejuvenate your cells and combat aging. He reveals his latest research on the contrasting effects of mild and high-pressure chambers on inflammation and cognitive performance. Listeners will learn about the revolutionary ways HBOT triggers stem cell activation and rewires genetic expression. Sonners also discusses how to enhance results by combining HBOT with fasting and red light therapies, all while navigating common misconceptions about oxygen toxicity.

79 snips
May 13, 2025 • 1h 11min
The New Science Behind Psychedelics, Exotic Shrooms, & Daily Flow-States | Matt Zemon : 1280
In this conversation, Matt Zemon, an expert on psychedelics and brain optimization, dives into how psychedelic mushrooms can unlock flow states and enhance mental clarity. He discusses the science behind psilocybin, its impact on neuroplasticity, and effective strategies for microdosing versus full doses. Zemon emphasizes the importance of using psychedelics safely and intentionally for emotional healing and personal growth. He also highlights the need for individual agency and integrates insights from both modern medicine and traditional wisdom.