The Human Upgrade: Biohacking for Longevity & Performance

I Lost 100 Pounds By Fasting Like THIS (The Missing Step) : 1387

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Dec 28, 2025
Discover the hidden fasting mistakes that can lead to muscle loss instead of fat loss. Learn how to flip the body's fat-burning switch for effective weight management. Explore the importance of muscle mass as a key to longevity and how poor habits can sabotage your progress. Get insights on breaking a fast correctly to maximize benefits. Dave shares practical tips from his own journey of losing 100 pounds, emphasizing the balance of diet, exercise, and mindset for optimal results.
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ANECDOTE

Turning Point After Failed Fasts

  • Dave Asprey recounts weighing 300 pounds and repeatedly regaining weight after early fasts.
  • He says learning the correct fasting method helped him lose over 100 pounds and keep it off for two decades.
INSIGHT

Muscle Determines Long-Term Metabolism

  • Muscle strongly influences resting metabolic rate and long-term fat balance.
  • Losing muscle during fasting can drop metabolism by 20–30% and drive rapid regain.
INSIGHT

Muscle As The Organ Of Longevity

  • Muscle secretes myokines that protect brain, bone, and heart health.
  • Higher muscle mass links to longer life and cellular repair, making muscle the 'organ of longevity.'
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