NEJM This Week

Dive into discussions about the rising challenges of obesity and diabetes, and the innovative treatments for spinal muscular atrophy that promise hope for infants. Learn about a significant case involving successful lung transplantation and the implications of metabolic dysfunction in liver disease. The podcast raises alarms about the erosion of public health initiatives and the transition toward private law in healthcare, all while sharing evocative personal stories of resilience in the face of medical challenges.

Delve into innovative treatments for chronic kidney disease and diabetes, along with groundbreaking trials for advanced breast cancer. Explore the complexities of hormone treatments in older patients while addressing autoimmunity and racial health disparities. The discussion also sheds light on the effects of profit-driven motives in healthcare. Uncover challenges in medical communication and the evolving role of physicians, all wrapped in personal reflections on how culture shapes medical aspirations.

Discover the latest breakthroughs in treating myeloma and mitochondrial DNA diseases, showcasing innovative personalized medicine strategies. Dive into the urgent need for improved motor vehicle safety and learn about groundbreaking advancements in cardiac surgery. Explore the complexities of autoimmune encephalitis and the significant implications of race-based evaluations in healthcare. Additionally, uncover the recent shifts in vaccination policies and their impact on public health narratives, emphasizing the intertwining of personal health journeys and societal influences.

Featuring articles on type 2 diabetes, gastric cancer, lung cancer, and malaria; a review article on competency-based medical education; a case report of a man with cough, dyspnea, and hypoxemia; and Perspectives on brain death in pregnancy, on the Supreme Court’s failure to protect trans minors, on real-world data, and on avocado and salt.

Recent advancements in treating gastric and gastroesophageal junction cancer highlight the potential of combining immunotherapy with traditional chemotherapy. Innovative approaches in pulmonary sarcoidosis and ex vivo heart resuscitation techniques spark fascinating discussions about ethics in medical care. The impact of AI on breast cancer detection raises questions about its clinical benefits, while a heartfelt narrative of a woman’s resilience after a heart transplant showcases the profound journey of transformation. Perspectives on evolving vaccine policies add another layer of depth to the conversation.

Explore the latest insights on managing mild asthma and cardiovascular risks. A fascinating discussion unveils new therapies for advanced breast cancer. Learn about juvenile idiopathic arthritis through the lens of a medical editor balancing research with patient care. Delve into a complex case involving neurological symptoms linked to a viral infection and the broader challenges in U.S. healthcare. Finally, discover how immigration policies affect caregiving and the urgent need for a more compassionate healthcare system.

Explore the powerful benefits of structured exercise for colon cancer survivors in boosting survival rates. Delve into the impact of climate change on health and discuss innovative strategies for treating obesity. Hear about the troubling trend of corporatization in U.S. healthcare and its effects on both patients and providers. A personal account reveals the emotional journey tied to an autopsy, examining the implications for medical practice. The conversation also touches on the anxiety faced by physicians in training while navigating the pressures of healthcare.

This week explores groundbreaking findings in treatment for cirrhosis and metastatic colorectal cancer. A study on gene therapy for infantile-onset Pompe disease shows promise, despite some challenges. The discussion on medical education highlights innovative changes and the impact of AI. Attention is drawn to the alarming rise of ultra-processed foods linked to health issues, with a strong plea for better regulation. A poignant case illustrates the systemic failures in healthcare that affect vulnerable individuals, revealing critical gaps in care.

The discussion covers groundbreaking treatments for mismatch repair-deficient tumors and HER2-mutant lung cancer. An urgent Corynebacterium diphtheriae outbreak is highlighted, alongside insights into hereditary kidney cancers. The risks and management of unruptured intracranial aneurysms are explored, featuring a case study on post-kidney transplant complications. The impact of AI on clinician autonomy raises thought-provoking concerns. Finally, emotional challenges faced by healthcare professionals, particularly in high-pressure environments like NICUs, are poignantly examined.

Discover breakthroughs in treatments for pulmonary fibrosis, obesity, and hemophilia B, emphasizing gene editing's role in rare diseases. Delve into the complexities of personalized medicine and the ethics surrounding gene therapy. Explore a gripping case of granulomatosis linked to puzzling ear symptoms and the pressing issue of health disparities affecting Black women in maternal care. The podcast also highlights the importance of advocacy and trust in navigating systemic inequities in healthcare.