NEJM This Week

The discussion covers groundbreaking treatments for mismatch repair-deficient tumors and HER2-mutant lung cancer. An urgent Corynebacterium diphtheriae outbreak is highlighted, alongside insights into hereditary kidney cancers. The risks and management of unruptured intracranial aneurysms are explored, featuring a case study on post-kidney transplant complications. The impact of AI on clinician autonomy raises thought-provoking concerns. Finally, emotional challenges faced by healthcare professionals, particularly in high-pressure environments like NICUs, are poignantly examined.

Discover breakthroughs in treatments for pulmonary fibrosis, obesity, and hemophilia B, emphasizing gene editing's role in rare diseases. Delve into the complexities of personalized medicine and the ethics surrounding gene therapy. Explore a gripping case of granulomatosis linked to puzzling ear symptoms and the pressing issue of health disparities affecting Black women in maternal care. The podcast also highlights the importance of advocacy and trust in navigating systemic inequities in healthcare.

Discover groundbreaking advancements in metabolic dysfunction and innovative approaches to lung nodule evaluation. Dive into the impact of race on healthcare diagnostics and the consequences of funding cuts on medical research. Explore the implications of immigration enforcement on patient rights and the struggles of vulnerable populations. Gain insights from clinical trials on birth outcomes and the evolving landscape of hemoglobin disorders, all while navigating critical conversations around equity and access in healthcare.

Delve into breakthroughs in treating pulmonary arterial hypertension and giant-cell arteritis. Discover the implications of losing Medicare subsidies and how it could threaten patient lives. Navigate the complexities of diagnosing cancer without a known primary site through compelling case studies. Explore innovative solutions for snakebite treatments while addressing primary care shortages in the U.S. Finally, hear a touching narrative about the challenges of caring for a loved one with Alzheimer's disease.