The Joe Cohen Show

Ryan Smith, co-founder of Tru Diagnostic, discusses longevity and biological aging tests. He highlights the most accurate tests and gives tips to reduce your pace of aging. They also talk about the immune system age, the MTHFR gene, and supplements for healthy aging.

Explore the impact of the ApoE gene on cognitive function and cardiovascular health, specifically its link to Alzheimer's disease. Discover the three major variants of the gene and how they influence the shape and function of the ApoE protein. Learn about other health issues related to the gene, including cardiovascular health, inflammatory responses, and longevity. Gain a comprehensive understanding of the ApoE gene and its importance in taking control of cognitive and overall health.

Emiel Bakker from Nootropics Depot joins the show to discuss the science behind dietary supplements. Topics include extraction methods for Lions Mane, navigating Bacopa varieties for memory enhancement, factors affecting Saffron's potency, and the difference between Ubiquinol and CoQ10.

Dr. Joseph Antoun from L-Nutra discusses the benefits of the fast-mimicking diet, including enhancing autophagy and reversing diabetes. They explore measuring autophagy, recommended fasting frequency, and nailing intermittent fasting. The podcast also highlights clinical trials on fasting mimicking diets, the challenges of longer fasting interventions, increasing stem cells, and the scientific evidence supporting fasting for diabetes. They discuss antioxidants, personalized supplement recommendations, and provide a discount code for fasting products.

Explore the fascinating world of the COMT gene, commonly dubbed the 'Warrior/Worrier' gene, and its influence on stress regulation, emotional resilience, and cognitive function. Dive into the discussion on the warrior and worrier variants and their effects on stress, working memory, and emotional resilience. Understand how understanding COMT activity can help tailor lifestyle choices and mitigate vulnerabilities.

Dr. Greg Nacarelli, expert in naturopathic medicine and genetics, discusses the future of personalized healthcare. He explores the interplay of genetics, environment, and lifestyle on our health. Greg highlights the value of understanding genetic profiles for personalized nutrition and health coaching. This episode offers invaluable insights into genomics and its impact on personalized medicine.

Dive deep into the intricate world of gut health with the pioneer himself, Dr. Steven Gundry.  Once dismissed as pseudoscience, the concept of 'leaky gut' has become a cornerstone of modern health understanding, and no one knows this better than Dr. Gundry.  In this enlightening episode, we unravel the real science behind leaky gut, the dangers of food sensitivities, and the profound effects of glyphosate on our system.  Beyond just understanding, Dr. Gundry shares actionable insights on optimizing your gut health to transform your overall well-being.  Whether you're a long-time health enthusiast or just beginning your journey, this episode offers a treasure trove of knowledge. Timestamps: (0:00) - Introduction (3:30) - Dr. Gundry's current ideal diet (9:12) - Autoimmune Disease Reversal & Leaky Gut  (17:08) - IgG Antibodies (27:29) - Other markers attributed to leaky gut (34:14) - Glyphosate and linoleic acid (48:20) - Top things to counteract food sensitivities (54:23) - LPa, ApoB and LDL Cholesterol (1:02:09) - Thoughts on diet studies with beans and whole grains (1:05:44) - Protein Restriction & Intermittent Fasting (1:11:08) - Fibers and gas

Welcome to SNPits, a new, short-form podcast series that takes you on a deep dive into specific genes, unraveling the science behind them and their impact on health.  In this episode, we tackle the MTHFR gene and its rise to fame. We explore how 'typos' in our genes, known as SNPs, influence our health, and dive into the debate surrounding one of the most studied genes in the world.  Is the MTHFR gene truly a culprit in conditions like heart disease and chronic fatigue, or is it a scapegoat?  Join us as we decode the science, bust some myths, and take a closer look at how our genes really affect our health. Whether you're a genetics guru or new to the subject, this episode offers an insightful and entertaining look at the complexity of our genetic code.  If you're interested in learning more about how your DNA and genetics affect your health, you can: - Check out SelfDecode: ⁠https://selfdecode.com/⁠ - Join Joe’s online community: ⁠https://thejoecohenshow.com/⁠  Links: Some studies found a 35-70% reduction in enzyme activity [R], and links between MTHFR variants, higher homocysteine, and: Heart disease and stroke [R, R] Fertility and pregnancy issues [R, R, R, R, R, R] Mental health issues [R] Migraines with aura [R, R] Some studies found no evidence for these links. Some even found the opposite results. In one study, MTHFR variants were linked to a lower risk of death from heart disease [R, R, R, R, R]

To celebrate the richness of this season, we've compiled the most powerful insights and the unforgettable moments into a special "Best of Season 3" episode. From experts breaking down complex health subjects to invaluable pieces of advice on achieving your healthiest self, this episode is your ultimate guide to the knowledge treasure of Season 3.

Is anxiety truly genetic? How do our genes and environment shape our response to stress? Are we all experiencing the world differently based on our unique biochemical make-up?  In this episode, Joe and Dr. Greg (SelfDecode Health Expert) dive deep into the realm of anxiety, answering questions from the SelfDecode community and unmasking the role our brain's biochemistry plays in the expression of anxiety. Joe and Greg discuss the role of mental health in overall wellness and highlight specific genes that you can look at to potentially help you get rid of anxiety. They then focus on the nutrients most commonly depleted under chronic stress and their links to anxiety, and break down some herbal supplements that work wonders in balancing our brain's neurotransmitters.  From the influence of specific genes like COMT and MTHFR, to the vital role of minerals like magnesium, zinc, and vitamin B6, this episode is a deep dive into the science of anxiety! If you're interested in learning more about how your DNA and genetics affect your health, you can: - Check out SelfDecode: ⁠https://selfdecode.com/⁠ - Join Joe’s online community: ⁠https://thejoecohenshow.com/⁠