The Joe Cohen Show

What’s the difference between genomics and genetics? How important is it to understand your genes when looking at optimizing your health? In this episode, Dr. Anil Bajnath and Joe delve into the world of DNA and their impact on our health. Dr. Bajnath breaks down complex health science concepts in a way that's easy to understand, while sharing his unique approach to healthcare. Some highlights of the episode include: ✔️ Understanding the difference between genomics (the study of all genes in our body) and genetics (the study of inherited traits). ✔️ The role of transcriptomics (how our genes behave) in understanding health issues like PTSD. ✔️ The impact of our gut health on our overall wellbeing. ✔️ The potential dangers of over-reliance on certain medications like statins. ✔️ The relevance of understanding lipid dynamics (how fat works in our bodies) for our heart health. ✔️ The value of a holistic approach to healthcare - focusing on treating the whole person, not just symptoms. Dr. Anil Bajnath is a Board-Certified Family Physician. Author of The Longevity Equation: The Step-By-Step Blueprint to Hack Your Genes, Optimize Your Health, And Master the Art of Existence. Dr.Bajnath currently serves as Adjunct Faculty with the Department of Clinical Research and Leadership at George Washington University School of Medicine. He is the CEO and founder of the Institute for Human Optimization Precision Medicine Research Group located in Annapolis, Maryland. If you're interested in learning more about how your DNA and genetics affect your health, you can: - Check out SelfDecode: ⁠https://selfdecode.com/⁠ - Join Joe’s online community: ⁠https://thejoecohenshow.com/⁠ 

Are supplements as strong as drugs? Dr. Tyler Panzner is this episode's guest, bringing his expertise on the role of genetics and supplements in combating common ailments such as IBS, anxiety, and insomnia.  As a champion for understanding our body’s pathways, Dr. Panzner's approach is transforming our understanding of chronic disease and health management. Dr. Panzner dives deep into the crucial topic of understanding and supporting our body’s most commonly mutated pathways, rather than getting caught up in an endless cycle of supplementing every gene. He also provides an exciting viewpoint, comparing gene mutations and their effects across all cells in the body. Joe and Tyler also point out the potential risks associated with the use of supplements and discuss the importance of understanding how they affect our bodies.  Dr. Tyler Panzner is a Ph.D. scientist trained in pharmacology, cancer, neuroscience, and inflammation research who has had a lifelong passion for understanding how substances affect the body. While his scientific training spans well over a decade, his passion for genetics and personalized medicine started ~6 years ago and he's pursued his goal of personalizing vitamin, supplement, and lifestyle regimes for each individual.  - Follow @drtylerpanzer on Instagram - visit www.drtylerpanzner.com - Check out SelfDecode - Join Joe’s online community - Follow Joe on Instagram & TikTok

Vince Giuliano is back, and this time, he’s discovered something about aging that may blow your mind. Vince Giuliano is living a healthy and active life at the young age of 93, and is committed to continue doing research on longevity and increasing lifespan even at this age! In this episode, Vince Giuliano and Joe discuss how supplements truly affect aging and how Vince has changed his perspective on longevity and the factors that affect it. Vince talks about his new theory, which compares the human body to a computer system, and shares how you can hack your body from the “virus” that is aging and live a healthy and optimal life at an old age. Vince Giuliano was a university professor at the State University of New York, a senior consultant working in a variety of fields at Arthur D. Little, Inc., Chief Scientist and COO of Mirror Systems, a software company, and an international Internet consultant. In various ways, he contributed to the Computer Revolution starting in the 1950s and the Internet Revolution starting in the late 1980s, and is now engaged in doing the same for The Longevity Revolution. He has published over 200 books and papers as well as over 430 substantive entries in his blog. - Find Vince Giuliano’s work at agingsciences.com - Check out SelfDecode - Join Joe’s online community - Follow Joe on Instagram & TikTok

In this episode, Joe sits down with biohacker and health expert, Anthony DiClementi. Best known for his revolutionary work in the biohacking space, Anthony shares a wealth of knowledge drawn from his 20+ years of experience biohacking himself and his clients with biohackingcoach.com. Anthony highlights the surprising, often overlooked factors contributing to bad health in the US, particularly focusing on the hidden toxins in our foods, the way cities are built, and the culture surrounding social interactions. This engaging conversation also delves into the dichotomy of medical practice and nutritional wellness, highlighting how conventional treatments often fail to address core health issues.  Joe and Anthony also discuss the importance of genetics in understanding sensitivities to environmental toxins, and discuss the current landscape of DNA companies. This episode of The Joe Cohen Show is a must-watch if you're looking to enhance your understanding of the unseen triggers impacting your health and wellness, and what you can do to completely optimize your health.

In this episode of The Joe Cohen Show,  Joe sits down with Chief Scientific Officer of MitoQ, Dr. Siobhan Mitchell. Siobhan shares her impressive academic and industry experience and knowledge to explore mood, cognitive function, and mitochondrial health. Her industry experience includes giants like Unilever, Nestle, PepsiCo, and Noom, where she worked on the fascinating effects of nutrition on mood and cognition. Siobhan and Joe do a deep dive into the serotonin-mood connection, helping us understand the genetic risk factors for depression and anxiety. Siobhan also shines a light on the underestimated significance of brain energy to mood and how mitochondrial strength plays a key role in this context. Siobhan also demystifies oxidative stress misconceptions and explains the impact of targeted antioxidants such as COQ10 and MitoQ. Finally, we delve into the 'Ozempic' effect of fiber on our gut health and how it could suppress your appetite naturally.  Siobhan illustrates her firm belief that understanding the food we consume can prevent numerous diseases - truly, food is our medicine. Explore these topics and much more as we discuss the human brain, mood, and the pioneering research in the field of mitochondrial health. - Visit mitoq.com - Check out SelfDecode - Join Joe’s online community - Follow Joe on Instagram & TikTok Timestamps: (0:00) - Intro (1:31) - Serotonin & Mood (12:56) - Brain Energy and mood (16:53) - Oxidative Stress & Muscle Growth (23:14) - Supplements that reach the brain (28:51) - CBT, physiology, and mood (32:00) - What are isoflavones? (38:43) - Difference between SSRIs and Tryptophan or 5HTP (50:04) - Brain energy and mitochondria health (56:15) - Fiber, Butyrate, and the Ozempic Effect (1:02:53) - Favorite probiotics (1:04:14) - Deep dive into fish oils (1:09:16) - Siobhan’s supplement stack

How can you use your biomarkers to create the optimal diet and supplement regimen for YOU? In this episode, Ari and Joe discuss how, similar to DNA, even optimal lab levels are personalized based on your unique body.  Ari talks about the problem with only focusing on 1 biomarker, and lets you in on important things to look out for when optimizing energy and focus.  They discuss the importance of AI and big data to health, and discuss the growing wearable market and how big of an impact this will have on optimizing health now and in the future.  Ari and Joe also discuss the importance of sleep and how it affects your recovery, and Ari shares his ultimate regimen for optimal sports performance. Ari Tulla is a San Francisco-based entrepreneur and the co-founder & CEO of the smart nutrition service, Elo, whose mission is to transform food from the leading cause of disease to medicine. Ari is also an active angel investor and advisor with a portfolio of 40 startups, including Virta Health, Good Eggs, and Ōura. - Visit elo.health - Check out SelfDecode - Join Joe’s online community - Follow Joe on Instagram & TikTok Timestamps: (0:00) - Intro (2:24) - Important biomarkers to test for (10:33) - HbA1C and Glucose hacks (29:40) - Homocysteine and the growing science behind it (39:01) - Is there one blueprint for optimal health? (46:50) - Sports performance vs. training for longevity (1:02:13) - Sleep and HRV (1:11:24) - The growth of health technology (1:20:44) - Biological age tests (1:26:55) - How to improve sleep

This episode was originally published on April 18th, 2017 on SelfHacked Radio - now known as The Joe Cohen Show. It's been 6 years since this episode aired, and yet a lot of health issues that were mentioned, alongside revolutionary health strategies that Dr. Gundry shares, are still more relevant than ever! In an episode that clearly shows Dr. Gundry was way ahead of his time, Joe and Steven Gundry discuss the prominence of leaky gut, how inflammation is the cause of the majority of health issues, and the root cause of all of this - LECTINS! You'll also discover the best ways to approach an elimination diet and how to optimize your gut health! - Check out SelfDecode - Join Joe’s online community - Follow Joe on Instagram Timestamps: (0:00) - Intro (15:52) - Lectins number one cause of gut issues? (22:15) - TH2 dominance and the immune system (27:55) - The process of healing your gut to introduce more foods (31:49) - Starting with a lectin-free diet (34:17) - Fiberous carbs vs non-fiberous carbs (44:17) - Low histamine foods relation to lectins (48:00) - The cannabinoid system and the CNR1 Gene (52:48) - Best probiotics to restore the gut (55:52) - Most important supplements to take (58:56) - Keto Plant Paradox (1:01:47) - Animal protein and mTOR

Does a fast-mimicking diet give you the same benefits as a 5-day water fast? How important is periodic fasting - also known as prolonged fasting - to your health? What is the best length of an intermittent fast? In this episode of The Joe Cohen Show, we dive deep into the world of fasting with our guest Dr. Joseph Antoun from L-Nutra, the pioneering company behind the revolutionary fast-mimicking diet. We discuss the science and mechanisms behind the fast-mimicking diet, exploring how it allows you to consume food and trick your body into thinking it’s fasting! Dr. Antoun also shares his thoughts on the best time to stop eating, how long your intermittent fast should be, and how these practices can improve your longevity. Dr. Joseph Antoun is CEO & Chairman of the Board of L-Nutra and Member of the Forbes Business Development Council. He's the former CEO of Health Systems Reform, a boutique consultancy aimed at improving public health by reforming health systems, management, and delivery. - Discover fasting at L-nutra - Check out SelfDecode - Join Joe’s online community - Follow Joe on Instagram & TikTok Timestamps: (0:00) - Introduction (1:48) - Longevity and fasting (7:10) - Fasting by nourishment vs. deprivation (13:06) - Periodic fasting vs. intermittent fasting (15:41) - Eating while fasting (21:37) - The structure of a fast mimicking diet (25:03) - Mimicking an intermittent fast (25:43) - The mechanisms behind fasting

Have you ever wondered what separates elite athletes and Navy SEALs from the rest of us? How do they optimize their physical and mental performance?  In this episode, Andrew Herr - who has led human performance and biotech strategy efforts for the U.S. military and ran R&D strategy efforts to get Navy SEALs ready to deploy - comes on the show to share his secrets to hack your recovery, improve your cognitive function, and optimize your stress management techniques. Plus, Andrew talks about the biological causes of jet lag, and how you can solve jet lag in less than a day! Some highlights of the episode include: ✔️ The one mistake even elite athletes make that might be wasting up to 50% of your workout value ✔️ Stress management techniques to improve your overall health ✔️ What supplements you can take to improve cognitive performance ✔️ The best thing you should focus on to enhance physical performance Andrew is the Founder & CEO of Fount. Fount runs the most comprehensive and customized health and performance programs in the world and has discovered full solutions to challenges like jet lag and PMS. Over the past decade, Andrew led human performance and biotech strategy efforts for the U.S. military, from running R&D strategy efforts to getting Navy SEALs ready to deploy. This background has made him a trusted adviser to pro sports teams, leading corporations from tech to finance, and world class scientific institutions. - Discover fount.bio - Find fount on instagram @fountbio - Check out SelfDecode - Join Joe’s online community - Follow Joe on Instagram & TikTok Timestamps: (0:00) - Intro (1:53) - Andrew's journey with the Navy SEALs (6:33) - Stress management techniques (15:20) - Optimizing gut health (28:26) - Thoughts on cholesterol (36:18) - Improving cognitive performance (38:15) - Improving physical performance (43:46) - Optimal ApoB numbers (48:27) - Solving jet lag

Is cholesterol good or bad for you? How should you treat your serum cholesterol levels in the blood? Is LDL-C the best marker to look at when analyzing your cardiovascular health?  In this episode, Joe dives deep into the complex and controversial world of cholesterol, examining the ongoing debate around its impact on cardiovascular health. First, he breaks down the different viewpoints that dominate the topic of cholesterol, discussing the positives and negatives of each one. He also delves into various factors contributing to cardiovascular disease and how cholesterol fits into the bigger picture. Then, he explores 10 lesser-known benefits of lipoproteins and cholesterol, including cellular repair, hormone production, mood improvement, and more. Joe explains the different markers we should consider when assessing cardiovascular risk, such as non-HDL Cholesterol, ApoB, and LDL particle size. Finally, Joe shares his own experiences and offers his own approach on how to deal with cholesterol on a personalized level. Check out SelfDecode Join Joe’s online community Follow Joe on Instagram & TikTok Timestamps: (0:00) - Introduction (01:09) - The cholesterol wars (02:55) - 10 Benefits of lipoproteins (10:46) - The tricky issues of cholesterol (18:11) - LDL, ApoB and Cardiovascular Disease (22:30) - The increase in evidence since 2015 (25:25) - Does lower cholesterol always mean better? (29:49) - Looking at the big picture