The Joe Cohen Show

SNPit #01 | The MTHFR Debate: Overhyped or Underestimated?

Aug 4, 2023
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INSIGHT

MTHFR Gene's Health Role

  • The MTHFR gene is crucial for the methylation process that regulates gene activity.
  • Its role in health issues like heart disease and fatigue stems from its effect on enzyme production.
INSIGHT

MTHFR SNP Impact on Enzyme

  • MTHFR gene codes for an enzyme that converts folic acid into methyl folate, vital for methylation.
  • Specific SNP mutations, mainly C677T, can reduce this enzyme's activity by up to 70%.
INSIGHT

Conflicting MTHFR Study Results

  • Reduced methylation raises homocysteine, linked to diverse health issues.
  • Despite this, some large studies find no link between MTHFR variants and these conditions.
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