The Neuro Experience

Dr. Matt Kaeberlein, a leading expert on aging biology, dives into the world of longevity supplements, spotlighting the hype around NAD+ IV therapy. He emphasizes the importance of being skeptical of self-proclaimed longevity experts and discusses the need for reliable information. Kaeberlein also critiques popular wellness trends, advocating for foundational health habits over questionable supplements. Additionally, he explores rapamycin's potential in promoting healthy aging, particularly its effects on ovarian function, and touches on the impact of GLP-1 medications on metabolic health.

It’s becoming harder to ignore: much of what we’ve been taught about food is outdated, oversimplified, or flat-out wrong. In this episode, I’m joined by Professor Tim Spector—renowned epidemiologist, gut microbiome expert, and founder of ZOE—to explore how the bacteria living inside us shape everything from chronic disease and metabolism to mood, menopause, and Alzheimer’s. We dive into why calorie counting fails, why probiotics might be useless, and how your gut could be the root of your brain fog, fatigue, and inflammation. Tim’s work is shaking up nutrition science and forcing us to rethink what “healthy” really means. This conversation will challenge the rules you’ve lived by—and show you how to eat for your biology, not someone else’s. *** I’m Louisa Nicola — clinical neurophysiologist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

In this enlightening discussion, Tim Spector, MD, a leading epidemiologist and co-founder of ZOE, reveals how gut health is crucial in preventing chronic diseases and boosting mental wellness. He explains why identical twins can have different health outcomes, the limitations of probiotics, and the power of prebiotics and fermented foods. Listeners will discover the profound link between nutrition and mood, and Tim shares his six essential habits for optimizing gut and brain health, making it clear that what you eat can transform your well-being.

Studies: https://pubmed.ncbi.nlm.nih.gov/40395689/ https://www.mdpi.com/2072-6643/14/5/921 https://jissn.biomedcentral.com/articles/10.1186/s12970-017-0173-z *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Hone Health – Take control of your hormones with at-home testing designed specifically for men. Get personalized insights and expert guidance to optimize your health and performance. Learn more at: https://honehealth.com/ Momentous – Science-backed supplements trusted by elite athletes and experts. Whether you’re looking to improve recovery, performance, or overall wellness, Momentous has you covered. Use code NEURO for 20% off your order: https://www.livemomentous.com/neuro Troscriptions – Unlock your cognitive potential with precision-dosed nootropics developed by medical experts. Whether you need more focus, clarity, or energy, Troscriptions offers innovative solutions. - Get 10% off: https://troscriptions.com/NEURO - https://troscriptions.com/discount/NEUROMAIL?utm_source=affiliate&utm_medium=email&utm_campaign=NeuroMail *** I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

In this insightful discussion, Dr. Nick Fabiano, a psychiatry resident and researcher at the University of Ottawa, reveals how creatine, often linked to sports performance, could be a groundbreaking treatment for depression. He explores its impact on brain chemistry and mood, while highlighting promising studies suggesting its effectiveness when combined with traditional therapies. Dr. Fabiano also delves into optimal dosing, potential cognitive benefits, and the need for further research, positioning creatine as a novel approach to mental health.

Discover how a simple change could reduce Alzheimer’s risk by 36%, particularly for women in midlife. The link between disrupted sleep and cognitive decline is unveiled, highlighting the importance of deep and REM sleep. Learn effective strategies to enhance sleep quality, including hormone balance and room temperature adjustments. Explore innovative techniques like cognitive behavioral therapy for insomnia, underscoring its value for optimal brain health. This is a crucial guide for safeguarding your mind as you age.

Stuart Phillips, a world-leading muscle scientist, joins to unravel the complexities of muscle building, particularly for women. He challenges conventional wisdom about protein intake, revealing that resistance training plays a crucial role alongside nutrition. Discover how benefits of muscle growth can happen across varied rep ranges, dispelling common myths. The conversation also delves into the significance of resistance training for brain health and discusses unique challenges faced by women during perimenopause, advocating for accessible health resources and empowering exercise practices.

Discover why women face a higher risk of Alzheimer's during menopause, as hidden hormonal and genetic factors come into play. Explore six powerful strategies to prevent cognitive decline, along with crucial testing recommendations often overlooked by doctors. Learn about the impact of nutrition, exercise, and even strength training on brain health. Delve into the benefits of specific foods, supplements, and stress management techniques to empower your cognitive future and keep Alzheimer's at bay.

In this conversation with Dr. Christopher Gardner, we debunk a common nutrition myth—that we need massive protein to build muscle. You might know Dr. Gardner from his twin study featured on Netflix, which explores how diets affect our bodies. We discuss protein requirements, diet quality, and sustainable eating. Plus, Dr. Gardner reveals insights from his DIETFITS Study and SWAP-MEAT trial, challenging conventional views on weight loss and plant-based diets. For science-backed nutrition insights, this conversation cuts through the hype and offers strategies that might change how you think about protein and diet. If you're interested in evidence-based nutrition that cuts through industry hype, this conversation provides scientific clarity and actionable strategies that might change how you think about protein and diet quality. Subscribe to The Neuro Experience for more evidence-based health insights. SponsorsA huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts:Hone Health – Take control of your hormones with at-home testing designed specifically for men. Get personalized insights and expert guidance to optimize your health and performance. Learn more at: https://honehealth.com/Momentous – Science-backed supplements trusted by elite athletes and experts. Whether you’re looking to improve recovery, performance, or overall wellness, Momentous has you covered. Use code NEURO for 20% off your order: https://www.livemomentous.com/neuroTroscriptions – Unlock your cognitive potential with precision-dosed nootropics developed by medical experts. Whether you need more focus, clarity, or energy, Troscriptions offers innovative solutions.- Get 10% off: https://troscriptions.com/NEURO- https://troscriptions.com/discount/NEUROMAIL?utm_source=affiliate&utm_medium=email&utm_campaign=NeuroMail Episode Timestamps: 00:00 Protein Myths & Leucine Threshold 02:58 Daily Protein RDA for Muscle Growth 06:17 Nitrogen Balance & Protein Recommendations 11:42 Nutrition vs. Exercise for Muscle-Building 16:37 Women’s Fitness: Protein & Resistance Training 20:14 DIETFITS Study: Diet Quality vs. Macronutrient Composition 39:17 SWAP-MEAT Trial: Plant-Based vs. Red Meat 50:04 Impact of Nutrition Education on Health 53:18 The Protein Flip & Plant-Based Menus 59:14 Netflix Twin Study: Addressing Misconceptions & Criticisms The Neuro Athletics Newsletter Instagram: @louisanicola_Twitter : @louisanicola_YouTube: @Louisa NicolaThe Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner, Dr Joe Zundell, Dr Ray Dorsy, Dr Dale Bredeson, Dr. Ben Bikman Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Heather Sandison, a naturopathic doctor and author specializing in neurodegenerative diseases, challenges the belief that Alzheimer's is inevitable, especially for women. She discusses how hormones, lifestyle, and informed choices can empower individuals against cognitive decline. Genetic factors like the ApoE4 allele’s impact on health are examined, along with the importance of a plant-forward diet and exercise. Sandison advocates for innovative treatments and accessible physical activities as key to enhancing cognitive health and reversing decline.