

How CREATINE is Used to Treat Depression
9 snips Jun 3, 2025
In this insightful discussion, Dr. Nick Fabiano, a psychiatry resident and researcher at the University of Ottawa, reveals how creatine, often linked to sports performance, could be a groundbreaking treatment for depression. He explores its impact on brain chemistry and mood, while highlighting promising studies suggesting its effectiveness when combined with traditional therapies. Dr. Fabiano also delves into optimal dosing, potential cognitive benefits, and the need for further research, positioning creatine as a novel approach to mental health.
AI Snips
Chapters
Transcript
Episode notes
Creatine Accelerates Depression Recovery
- Creatine supplementation can improve depressive symptoms faster when paired with antidepressants or therapy.
- Depression may involve brain energy deficits which creatine helps restore.
Creatine's Role in Brain Energy
- Depression involves impaired brain energy metabolism causing low energy and symptom exacerbation.
- Creatine supplementation replenishes brain energy stores, relieving some depressive symptoms.
Creatine Benefits Beyond Depression
- Creatine may benefit various mental disorders including ADHD and schizophrenia by improving cognitive impairments.
- In bipolar disorder, creatine can trigger hypomania, showing its strong effect on brain energy.