The Curbsiders Internal Medicine Podcast

#392 Live! Opioid and Xylazine Withdrawal in the Hospital

Apr 26, 2023

45:27

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Episode notes

Introduction

2min

Xylazine Carointoxication: A Case Study

3min

The Unpure Drug Supply

3min

The Cytotoxic Effect of Xylazine on Wounds

6min

How to Prevent Opioid Overdoses

2min

How to Manage Opioid Withdrawal in the Inpatient Ward

5min

The Role of Benzodiazepine in Anxiety Disorder Management

4min

How to Manage Acute Pain in a Patient With Opioid Dependence

5min

Precipitated Withdrawal

4min

10.

How to Start a Low Dose Induction Conversation With Patients

2min

11.

The Role of Harm Reduction in Treatment of Xylazine Use Disorder

3min

12.

How to Calculate the Dose of Lightness Therapy

7min

Dominate opioid and xylazine (aka tranq) withdrawal in the hospital with expert insights from Dr. Joseph D’Orazio (@dorazepam) recorded LIVE! at Pennsylvania Hospital Grand Rounds in Philadephia, PA. Xylazine, an alpha-2 adrenergic agonist, has emerged as a frequent contaminant in the opioid supply with a distinct withdrawal syndrome. You’ll learn to manage this common withdrawal syndrome while also addressing acute pain complaints and opioid withdrawal.

Sorry, no CME for this episode, but check out CME for past episodes at curbsiders.vcuhealth.org.

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Show Segments

Intro
Xylazine basics
Management of xylazine withdrawal
Opioid withdrawal and acute pain
Outpatient considerations for xylazine
Audience questions
Outro

Credits

Writer and Producer: Matthew Watto MD, FACP
Infographic and Cover Art: Matthew Watto MD, FACP
Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
Reviewer: Emi Okamoto MD
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: Joseph D’Orazio MD

Full transcript available HERE

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The Curbsiders Internal Medicine Podcast

#392 Live! Opioid and Xylazine Withdrawal in the Hospital

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