Dom D’Agostino, an Associate Professor at the University of South Florida and an expert in ketosis research, discusses the ins and outs of the ketogenic diet. He gives practical tips on optimizing health through training, supplements, and intermittent fasting. The conversation explores how genetic factors influence responses to ketogenic diets and examines the long-term effects on thyroid function. With intriguing insights on measuring ketones and the diet's impact on appetite control, D'Agostino delivers a comprehensive look at this popular health trend.
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question_answer ANECDOTE
Recent Research
Dom D'Agostino's recent work focuses on applying lab research to humans, including projects with NASA.
His research involves studying the effects of extreme environments on human physiology, like in the NASA Extreme Environment Mission Operations (NEMO) project.
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Intermittent Ketosis Benefits
Try intermittent ketosis for metabolic flexibility, even if you tolerate carbs well. Achieve a glucose ketone index of 1-2 by restricting calories and combining a ketogenic diet with time-restricted feeding.
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Recommended Keto Resources
To learn about modified keto, read "The Art and Science of Low Carbohydrate Performance" by Jeff Volek and Stephen Phinney.
Also check out "The Ketogenic Bible," "Keto Answers," and "The Ketogenic Diet and Metabolic Therapies."
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Keto Answers is a detailed guide to the ketogenic diet, covering its mechanisms, benefits, and how to customize it for individual needs. The book addresses 268 common questions about keto, from basic concepts like ketosis to advanced topics such as keto during pregnancy. It provides practical advice on overcoming challenges and maintaining a keto lifestyle.
Ketogenic Diet and Metabolic Therapies
Ketogenic Diet and Metabolic Therapies
Susan Masino
This book provides a deep dive into the scientific underpinnings of ketogenic diets and their therapeutic applications. It explores the metabolic pathways involved in ketosis, the effects on various physiological processes, and the potential benefits for various health conditions. The book is a valuable resource for researchers, healthcare professionals, and individuals interested in the scientific basis of ketogenic diets. It offers a comprehensive overview of the current research and clinical applications of ketogenic therapies. The book's detailed scientific approach makes it a valuable resource for those seeking a deeper understanding of the subject.
The Art and Science of Low Carbohydrate Performance
A Revolutionary Program to Extend Your Physical and Mental Performance Envelope
Jeff Volek
Stephen D. Phinney
This book provides a detailed exploration of how a well-designed ketogenic diet can enhance athletic performance by improving fuel efficiency and reducing the risk of hitting a performance plateau. It addresses common myths about low-carb diets and offers practical advice for athletes looking to improve their endurance and recovery.
The Ketogenic and Modified Atkins Diets
Treatments for Epilepsy and Other Disorders
Eric Kossoff, MD
This book provides detailed information on the use of ketogenic diets, including the Modified Atkins Diet, as treatments for epilepsy and other neurological conditions. It covers the history, implementation, and benefits of these diets, along with practical advice for patients and healthcare providers.
The ketogenic bible
2021~ VER — Harry Potter 20th Anniversary: Return to Hogwarts 2021 Pelicula Completa Espanol
The Ketogenic Bible provides an exhaustive, science-based overview of the ketogenic diet, covering its benefits for health concerns like obesity and diabetes, as well as its effects on athletic performance. The book includes practical tips, advice for beginners, and over 75 recipes. It is based on extensive research conducted by the authors at the Applied Science and Performance Institute.
Back by very popular demand for a special AMA episode, ketosis expert Dom D’Agostino joins Bob Kaplan, Peter’s Head of Research, to address many lingering questions about the ketogenic diet, exogenous ketones, and exercise for overall health. Dom also shares valuable insights from his personal experience with training, supplements, intermittent fasting, and other nutritional strategies to optimize his own health and performance. If you’re not a subscriber and listening on a podcast player, you’ll only be able to hear a preview of the AMA. If you’re a subscriber, you can now listen to this full episode on your private RSS feed or on the website show notes page.
We discuss:
Dom’s recent and ongoing projects [3:00];
Benefits of a ketogenic diet for an otherwise healthy person [7:00];
Book recommendations to become more knowledgeable about a ketogenic diet [11:30];
Best devices for measuring ketones [13:45];
Genetic factors that influence how someone responds to the ketogenic diet [24:45];
Ketogenic diet for those with the APOE e4 allele [28:15];
Impact of long-term ketogenic diets on thyroid function [34:25];
Low-carb and ketogenic diets for appetite control and weight management [39:00];
Ketogenic diet and the microbiome [43:00];
Comparing monounsaturated fat versus saturated fat on the ketogenic diet [45:55];
Implications of long-term genetic and epigenetic adaptations to a ketogenic diet [47:45];
Why some people see a rise in LDL-C and LDL-P when on a ketogenic diet and what they can do about it [50:15];
Should someone with familial hypercholesterolemia consider a ketogenic diet? [55:00];
Exogenous ketones—benefits, therapeutic uses, and ketone supplements that Dom has tested [56:45];
Ketogenic protocols for management of traumatic brain injuries [1:06:00];
Comparing the benefits and therapeutic uses of various medium-chain fatty acids—caprylic acid (C8), capric acid (C10), MCT oil, and coconut oil [1:08:45];
Nootropics, caffeine, and other stimulants [1:16:15];
Supplemental use of testosterone, DHEA, and creatine for muscle growth and performance [1:23:45];
Impact of fasted-state training on strength and performance [1:30:15];
Stacking exogenous ketones with MCTs for optimal effectiveness [1:33:30];
BCAA supplements during a fast for muscle preservation [1:35:45];
What app is Dom using to track his macros? [1:42:00];
Getting enough micronutrients while on a ketogenic diet [1:47:15];
Ideal macros and getting enough protein for strength training in ketosis [1:48:15];
Pros, cons, and ideal macros of one meal a day [1:51:15];
Dom’s take on “carb backloading” [1:54:45];
Dom’s take on “carb up” days for ketogenic dieters [2:01:00];
Dom’s thoughts on the carnivore diet and the paleolithic ketogenic diet [2:05:30];
Advantages of the ketogenic diet for extreme endurance athletes [2:10:30];
Impact on strength, power, and performance during the adaptation period of the ketogenic diet [2:14:00];
Fasted-state elevation in growth hormone and its impact on training [2:17:45];
Is it possible to build muscle on a ketogenic diet? [2:23:30];
Why Dom took a year off from weight training [2:28:00];
What does Dom do for cardio exercise? [2:30:45];
Protocols for hard training recovery [2:33:15];
Dom’s personal approach to fasting, time-restricted eating, and sleep [2:35:45];
People, books, and other resources that shaped Dom’s training and nutrition [2:38:45]; and
The Peter Attia Drive 
