
The Peter Attia Drive
Expert insight on health, performance, longevity, critical thinking, and pursuing excellence. Dr. Peter Attia (Stanford/Hopkins/NIH-trained MD) talks with leaders in their fields.
Latest episodes

142 snips
Jun 23, 2025 • 2h 16min
#354 – What the dying can teach us about living well: lessons on life and reflections on mortality | BJ Miller, M.D. and Bridget Sumser, L.C.S.W.
BJ Miller, a hospice physician and co-founder of Mettle Health, and Bridget Sumser, an expert social worker in serious illness, discuss profound insights from their work in end-of-life care. They explore the emotional and physical realities of dying, the importance of candid conversations about mortality, and how many await hospice care too late. With reflections on fear, forgiveness, and how dying can teach the living to embrace life more fully, they emphasize the transformative potential of understanding our mortality.

166 snips
Jun 16, 2025 • 20min
#353 - AMA #72: Fasting: benefits for body composition and disease prevention, potential risks, and Peter’s updated practical framework
This discussion dives into the evolving landscape of fasting, examining its types and health effects. Key benefits like improved body composition, metabolic health, and potential disease prevention are highlighted. The importance of adapting scientific opinions in medicine is emphasized, alongside a practical framework for fasting. Various methods such as intermittent and alternate day fasting are explored, shedding light on their protocols and historical perspectives. The episode balances science with personal insights, creating a thought-provoking dialogue.

182 snips
Jun 9, 2025 • 2h 23min
#352 ‒ Female fertility: optimizing reproductive health, diagnosing and treating infertility and PCOS, and understanding the IVF process | Paula Amato, M.D.
In this insightful discussion, Dr. Paula Amato, a leading expert in reproductive endocrinology, dives into the complexities of female fertility. She explains how hormonal changes regulate the menstrual cycle, and why both partners should be evaluated in infertility cases. The conversation reveals the impact of age and lifestyle on reproductive health, while exploring advances in IVF, including egg freezing and genetic testing. Dr. Amato also addresses PCOS treatment options and highlights the need for early intervention to enhance fertility prospects.

257 snips
Jun 2, 2025 • 2h 19min
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.
Paul Turek, a leading expert in male fertility and the founder of the Turek Clinic, dives into the intricate world of male reproductive health. He reveals the complex journey sperm undertake to fertilize an egg and discusses environmental factors like heat and toxins that can impair sperm quality. Turek also debunks myths surrounding testosterone replacement therapy and its effects on fertility, offering insights into preserving reproductive health. The conversation covers new advancements in reproductive medicine, including genetic testing and innovative treatments.

494 snips
May 26, 2025 • 1h 45min
#350 ‒ Injury prevention, recovery, and performance optimization for every decade | Kyler Brown, D.C.
Kyler Brown, a sports rehab chiropractor and co-founder of the training program 10 Squared, dives into injury prevention and recovery tailored for every life stage. He discusses how overlooked movement patterns can lead to chronic issues and presents a framework for personalized rehab strategies. The psychological aspects of recovery, particularly fear and mental barriers, are also explored. Kyler emphasizes the importance of individualized treatment plans, engaging stories, and actionable tools for long-term health and performance.

218 snips
May 19, 2025 • 11min
#349 - AMA #71: Building strength and muscle mass: how to optimize training, nutrition, and more for longevity
Explore the vital role of muscle mass and strength in boosting longevity and health. Discover essential training strategies like progressive overload and safe practices tailored for every fitness level. Learn why muscle matters for metabolic health and injury prevention. Delve into key nutrition tips, including optimal protein intake and the role of creatine. Enjoy a humorous anecdote from a school visit, illustrating children's curiosity about health. This insightful discussion is packed with practical advice for optimizing your fitness journey.

381 snips
May 12, 2025 • 2h 13min
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.
Dr. Rachel Rubin is a board-certified urologist and a leading expert on sexual health, particularly for women. She discusses the often-ignored complexities of women’s sexual health, hormonal changes during menopause, and the critical need for personalized hormone replacement therapy (HRT). Dr. Rubin clarifies misconceptions surrounding HRT and emphasizes the benefits of local vaginal therapies. She also highlights the significant health risks of menopause, including osteoporosis and cognitive decline, advocating for improved awareness and education in this field.

300 snips
May 5, 2025 • 33min
#347 – Peter’s takeaways on mastering sleep, dealing with chronic pain, developing breakthrough cancer drugs, transforming healthcare with AI, advancing radiation therapy, and healing trauma | Quarterly Podcast Summary #5
Dive into the fascinating world of health and wellness! Discover how trauma influences behavior and the healing journey. Learn effective strategies for mastering sleep through cognitive behavioral therapy. Unpack misconceptions around radiation therapy in cancer treatment. Explore the latest advancements in oncology thanks to AI technology. Plus, insights on managing chronic pain and the impact of emotional trauma on mental health. This summary is packed with actionable knowledge and fresh perspectives on complex health topics!

220 snips
Apr 28, 2025 • 2h 6min
#346 - Scaling biotech and improving global health: lessons from an extraordinary career in medicine | Susan Desmond-Hellmann, M.D., M.P.H.
Dr. Susan Desmond-Hellmann, a physician and scientist with a rich career in oncology and global health, shares her incredible journey through medicine. She recounts her experiences during the early AIDS crisis and her pivotal role in developing cancer therapies like Herceptin. The discussion deepens around the potential of AI in transforming healthcare, the innovations at Genentech, and the complexities of navigating drug development. Susan also reflects on leadership in global health, emphasizing the importance of teamwork and trust in public health initiatives.

470 snips
Apr 21, 2025 • 2h 47min
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.
Sean Mackey, a renowned pain medicine professor at Stanford, dives deep into the complex nature of chronic pain. He discusses the evolutionary purpose of pain and how different individuals experience it uniquely. Mackey explores various treatment strategies, from traditional medications to innovative techniques like TENS, emphasizing the intertwined nature of physical and psychological factors. He also shares insights on the impact of sleep on pain sensitivity and the historical evolution of pain management, providing a comprehensive view of this multifaceted challenge.