The Peter Attia Drive

Abbie Smith-Ryan, an exercise physiologist and researcher at UNC, discusses vital aspects of women's health across different life stages. She highlights how early exercise lays the groundwork for lifelong health in girls and the importance of tailored nutrition and training throughout the menstrual cycle. Abbie shares insights on managing perimenopause, focusing on strategies for optimal muscle and metabolic health. Additionally, she addresses practical training programs for busy women, while debunking myths and advocating for better awareness of hormone therapy's benefits.

James Clear, an acclaimed author and speaker renowned for his work on habits and behavior change, delves into the intricacies of habit formation. He discusses how genetics, environment, and social circles shape our behaviors. Clear emphasizes the significance of systems over goals and introduces his 'Four Laws of Behavioral Change' for effective habit creation and breaking. Exploring concepts like identity-based habit change and the impact of social influences, he provides practical strategies to foster positive habits and eliminate negative ones.

Arthur Brooks, a Harvard professor and bestselling author, delves into the complexities of happiness, distinguishing it from fleeting emotions. He highlights three macronutrients of happiness: enjoyment, satisfaction, and purpose. The conversation explores how societal pressures like fame and success can undermine true well-being. Brooks offers practical tools, including the reverse bucket list and metacognition, to help cultivate a meaningful life and shares his personal journey to greater happiness. It's a fascinating mix of science, philosophy, and actionable insights!

This lively AMA covers diverse health topics, from lifespan interventions to exercise as the top motivator for longevity. Discover the Centenarian Decathlon, a framework that helps midlife patients set long-term goals. Peter emphasizes treating high apoB levels even in seemingly healthy individuals and shares effective strategies for blood pressure management. Time-restricted eating and nuanced approaches to hormone therapies are also explored. Plus, insights on exercise for busy schedules and the importance of early chronic disease screening make for a compelling listen.

Dominic D'Agostino, Ph.D., is a leading neuroscientist specializing in metabolic therapies like ketogenic diets and hyperbaric oxygen. He delves into nutritional versus supplemental ketosis and offers practical tips to achieve ketosis effectively. The discussion covers the ketogenic diet's impact on weight loss and neurodegenerative diseases such as cancer and Alzheimer's. Additionally, Dominic explores exogenous ketones and their role in cognitive enhancement, while revealing insights on common mistakes and the benefits of hyperbaric oxygen therapy for brain injuries.

Carole Hooven, a human evolutionary biologist and former Harvard lecturer, dives deep into the fascinating world of testosterone and its impact on male development and behavior. She explains how prenatal testosterone influences brain development and lifelong behavioral patterns, highlighting unique aggression styles and play behaviors. Carole shares insights on the implications of modern society on male aggression, the necessity of testosterone therapy, and her own experience with hormone therapy. She also discusses her upcoming book on masculinity and cultural narratives.

Walter Green, a philanthropist and founder of the Say It Now movement, shares transformative insights from his life and work. He emphasizes the importance of gratitude, urging people to express appreciation to loved ones before it's too late. Walter discusses his challenging childhood, the lessons learned from mortality, and the concept of 'finishing strong.' He also offers practical advice on intentional living, defining success, and setting boundaries to prioritize meaningful relationships. His journeys of gratitude culminate in heartfelt tributes to friends, inspiring others to do the same.

Dr. Antonio Bianco, a renowned physician-scientist and former President of the American Thyroid Association, dives deep into thyroid physiology. He discusses the complex roles of deiodinase enzymes in regulating thyroid hormones and their implications for patient care. The conversation highlights the inadequacy of conventional TSH testing, the impact of genetics on thyroid function, and the ongoing debates over treatment methods for hypothyroidism. Bianco also shares insights into why patients may feel unwell despite 'normal' lab results and the need for personalized treatment approaches.

Dive into the surprising science of dietary fiber! Discover the distinct roles of soluble and insoluble fibers in digestion and weight management. Learn why not all fibers are created equal and how cooking influences resistant starch. Peter Attia challenges traditional beliefs about fiber and offers evidence-based insights on its true health benefits, including its impact on glycemic control and cardiovascular risk. Get ready for a personalized approach to maximizing your dietary fiber intake!

Dr. Sally Greenwald, an OB-GYN specializing in women's sexual health, delves into the intricate world of female sexual wellness. She discusses the importance of sexual health for overall well-being, exploring the physiology behind desire and arousal. Highlights include navigating the orgasm gap, practical strategies to enhance intimacy, and the impact of hormones during perimenopause. Sally also addresses common misconceptions, effective communication with partners, and the latest in contraceptive and hormone therapy options, providing vital insights for women and their partners.