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Proteinuria Screening
- Treat proteinuria on a UA as a screening test, not a quantitative measure.
- Quantify proteinuria with a urine protein-to-creatinine ratio (UPCR).
Optimizing UPCR Collection
- Collect UPCR in the morning to minimize transient orthostatic proteinuria.
- Check specific gravity as dilute urine falsely lowers and concentrated urine falsely elevates proteinuria.
Nephrotic Syndrome Definition
- Nephrotic syndrome is defined as nephrotic range proteinuria with low albumin and edema.
- Additional features may include hyperlipidemia and thrombosis.