The Intern At Work: Internal Medicine

17. Ask a Fellow: Pulmonary Renal Syndrome

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Dec 16, 2018
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INSIGHT

Definition Of Pulmonary Renal Syndrome

  • Pulmonary renal syndrome manifests as simultaneous respiratory failure and renal failure, typically diffuse alveolar hemorrhage and glomeronephritis.
  • These manifestations usually occur at the same time, defining the syndrome's clinical presentation.
ADVICE

Detailed History Is Crucial

  • Take a detailed history focusing on respiratory symptoms, systemic inflammation, and potential underlying autoimmune signs.
  • Ask about drug use to identify mimics, as some drugs can induce ANCA antibodies.
ADVICE

Key Physical Exam Findings

  • During physical exam, assess respiratory distress signs and look for systemic features like palpable purpura or rash to suggest the underlying cause.
  • Recognize that renal failure signs may be subtle, mostly mild edema or systemic manifestations depending on etiology.
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