The Curbsiders Internal Medicine Podcast #170 Hypernatremia is Easy with Joel Topf MD
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Sep 2, 2019 AI Snips
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Hypernatremia Simplified
- Hypernatremia is easier to manage than hyponatremia, with no pseudo variants or critical rate concerns.
- If sodium is high, it just is; no complex differential like in hyponatremia is needed.
Hypercalcemia Causes Nephrogenic DI
- Hypercalcemia causes nephrogenic diabetes insipidus by disrupting kidney's salt gradient.
- It acts like a loop diuretic, impairing water reabsorption despite ADH presence.
DDAVP Differentiates Diabetes Insipidus
- Use DDAVP to distinguish central vs nephrogenic diabetes insipidus.
- A sharp decrease in urine output after DDAVP indicates intact kidney response and central DI.