Siim Land Podcast #440 GENETICS Based Supplements You Should AVOID - Dr Tyler Panzner
Feb 15, 2025
Dr. Tyler Panzner, an expert in genetics and personalized medicine, shares insights on how our genes influence supplement effectiveness. He reveals the genetic factors affecting caffeine and creatine metabolism. The discussion also explores the complexities of supplements like glycine and the impact of diet on food sensitivities. Tyler highlights the importance of individualized nutrition strategies, particularly regarding vitamin D and omega-3s, while addressing common misconceptions in the realm of health supplements.
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Tyler's Path to Personalized Medicine
- Dr. Tyler Panzner's interest in science started with a fascination for animals and later shifted to molecular biology.
- He experimented with supplements and biohacking, even making and selling pre-workout in college.
Caffeine Metabolism and Genetics
- Caffeine metabolism is complex, involving the breakdown of caffeine itself and the neurotransmitters it releases.
- Genetic variations in COMT, MAO, and adenosine receptors impact caffeine sensitivity and anxiety.
Creatine Considerations
- Creatine, while generally safe, can cause anxiety or hair loss in individuals sensitive to adrenaline or with high DHT levels.
- Consider combining creatine with DHT-lowering supplements like saw palmetto or reishi mushroom.
