Chapters
Transcript
Episode notes
1 2 3 4 5 6
Introduction
00:00 • 3min
The Benefits of Early Administration of Four Factor Prothrombin Complex Concentrate in Patients With Trauma at Risk of Massive Transfusion
02:30 • 3min
The Exclusion of Trauma Patients
05:49 • 2min
The Four-Factor PCC Study and the Safety Outcomes
07:23 • 3min
The Limitations of 24-Hour Blood Product Use
10:08 • 3min
The ProCoAG Trial on Four Factor PCC and Trauma Patients
12:55 • 4min
Background: Hemorrhage is the leading cause of mortality in trauma patients. Interventions such as early application of hemorrhage control, tranexamic acid, reduction of crystalloid fluid administration and balanced ratio blood product transfusion have improved many patients’ outcomes. However, mortality still remains high due to trauma-induced coagulopathy. Some clinicians have advocated for early administration of 4-factor ...