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Quick takeaways
- Oral beta-lactams, including cephalosporins, can be a suitable treatment option for respiratory infections like COPD exacerbations or uncomplicated cellulitis.
- The use of oral beta-lactams in osteomyelitis and endocarditis requires careful patient selection and adherence to guidelines.
Deep dives
Cephalosporin Pearls for Oral Therapy
When it comes to first-generation cephalosporins, cephalexin is commonly used, but cephedroxil is an oral cephalosporin with great bioavailability that is often overlooked. It can be dosed twice daily and may be worth considering more often. Additionally, for automatic IV-to-PO protocols, some hospitals are converting cephradine to cephalexin for urinary tract infections if the organism is susceptible. This excludes bacteremia. For respiratory infections, such as COPD exacerbations or uncomplicated cellulitis, oral beta-lactams, including cephalosporins, can be a suitable treatment option.
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Discover
highlights
Listen to the best highlights from the podcasts you love and dive into the full episode