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#35 – Oral Beta-Lactams, Are We Serious?
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OVIVA and Osteomyelitis: A Randomized Trial
OVIVA was a randomized trial about a thousand patients, included patients that had a variety of bone injections and a variety of source control strategies. Patients were randomized to either oral antibiotics or continued IV antibiotics to complete six weeks of primary therapy. Over 50% of the organisms in this study were staphylococci; there was a pretty wide distribution of grand positives and good negatives.
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