Core IM | Internal Medicine Podcast

#104 Guideline-Directed Medical Therapy for HFrEF Part 1: 5 Pearls Segment

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May 11, 2022
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ADVICE

Patient Education for Beta-Blockers

  • When prescribing beta-blockers, educate patients on what to expect, like lower blood pressure.
  • Clearly explain the benefits and address any misconceptions to improve adherence.
INSIGHT

PARADIGM Trial Limitations

  • The PARADIGM trial's design, comparing ARNI to an ACE inhibitor and using a long run-in period, may overestimate ARNI's real-world benefit.
  • It's important to consider these limitations when interpreting the results.
ADVICE

MRA Choice in Heart Failure

  • In heart failure patients, consider using eplerenone over spironolactone as it has similar efficacy.
  • This avoids side effects like gynecomastia and sexual dysfunction.
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