
The Genius Life 534: How Women Can Age With More Energy, Clarity, and Confidence | Mindy Pelz, DC
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Dec 15, 2025 Mindy Pelz, DC, a bestselling author and expert in women's health, discusses the transformative journey of menopause. She explains how menopause rewires the brain, enhancing clarity and confidence, and presents the grandmother hypothesis, illustrating the vital role of post-reproductive women in society. Mindy shares insights on how fasting and a primal diet can empower menopausal women, advocating for strategic fasting practices and lifestyle changes to optimize metabolic health. Her nuanced view on hormone replacement therapy emphasizes personalized approaches alongside lifestyle adjustments.
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Menopause As Brain Rewiring
- Menopause rewires the brain, shedding people-pleasing circuits and growing neurons for leadership roles.
- This neurochemical shift may have evolved to prepare post-reproductive women for cultural leadership and caregiving.
The Grandmother Hypothesis Explained
- The grandmother hypothesis suggests postmenopausal women evolved to forage, feed families, and transmit culture.
- This role likely supported human survival and accelerated language and brain development.
Storytelling Boosts Brain Chemistry
- Storytelling by elders stimulates acetylcholine, dopamine, serotonin, oxytocin and other neurotransmitters in both teller and listener.
- This neurochemical interaction may preserve memory and foster language learning in children.











