

#013 How The Gut Microbiota Affects Our Health with Dr. Erica & Dr. Justin Sonnenburg
44 snips Sep 3, 2015
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Humans As Microbial Ecosystems
- Humans have 10 times more bacterial cells than human cells and 100 times more bacterial genes than human genes.
- We function as ecosystems hosting a complex microbial community critical to immune, metabolic, and brain functions.
Gut Microbes Shape Immunity
- The gut hosts the largest number of immune cells interacting with gut microbes, influencing immune balance.
- Gut microbes set immune system activity levels body-wide, affecting infection response, vaccines, and autoimmune diseases.
Fiber Feeds Gut Microbes
- Dietary fiber feeds gut microbes that produce short-chain fatty acids, which regulate immune activity positively and reduce inflammation.
- Lack of fiber starves microbes, leading to hyperactive immune states linked to inflammatory and autoimmune diseases.