Episode #292: Kiran Krishnan: From Gut to Brain: The Impact of Your Microbiome

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Dec 13, 2024

Join Kiran Krishnan, a renowned research microbiologist with over 20 years in gut health, as he explores the fascinating connection between gut and brain health. He discusses the surprising roles of different bacteria, pitfalls of standard probiotics, and the advantages of spore-based and psychobiotics. Kiran highlights lifestyle impacts on gut health, the critical gut-brain axis, and actionable steps for improving overall well-being. Discover how dietary choices and stress management can transform your health journey!

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INSIGHT

Gut Microbiome and Organ Function

The human digestive system, from mouth to liver, relies on specific microbial populations for optimal function.
Dysbiosis, or microbial imbalance, in any part of the gut can lead to organ dysfunction and widespread health issues.

INSIGHT

Functional Redundancy and Microbiome Diversity

Individual gut microbiomes can be vastly different yet equally healthy due to functional redundancy.
Focus on microbial functions (e.g., short-chain fatty acid production) rather than specific species for assessing gut health.

INSIGHT

Microbiome Diversity and Dietary Adaptations

Aim for diversity in gut bacteria for optimal resilience and ability to process various foods.
Regional dietary adaptations may influence microbiome composition.

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Is Your Microbiome Sabotaging Your Health?

I am joined by Kiran Krishnan as we delve into the fascinating world of gut health and probiotics! Kiran explains the crucial roles of different types of bacteria in maintaining gut health, the pitfalls of common probiotic supplements, and introduces us to spore-based probiotics and psychobiotics. He offers actionable insights into improving gut health through diet, exercise, and the right supplements.

Kiran Krishnan is renowned research microbiologist and an expert in the human microbiome. With over two decades of experience in the field and has been at the forefront of groundbreaking research, focusing on the critical role our gut microbiome plays in overall health. Visit https://justthrivehealth.com and use code NAT20 for a discount.

What We Discuss

Understanding Gut Health and the Human Microbiome 00:27
The Role of Microbes in Digestive Health 01:11
Microbiome Diversity and Its Impact on Health 03:34
Challenges with Gut Testing Kits 04:23
Functional Redundancy in the Microbiome 05:29
Balancing Microbial Populations for Optimal Health 08:40
The Importance of Microbiome Diversity 10:10
Misconceptions About Pathogens in the Gut 11:23
The Impact of Modern Lifestyle on Gut Health 19:26
The Gut-Brain Connection 27:04
Inflammation and the HPA Axis 32:06
Neurodegeneration and Protein Misfolding 32:55
Impact of Endotoxins on Neurotransmitters 34:27
Gut-Brain-Liver Axis and Energy Balance 35:33
The Role of Sleep and BDNF in Brain Repair 40:44
Rising Prevalence of Neurological Disorders 41:51
Probiotics and Gut Health Solutions 43:57
The Importance of Fiber 54:04
Conclusion and Product Recommendations 01:00:48

Thank you to our sponsors for making this episode possible:

Zona Health: Visit https://www.zona.com/ and use code NAT24 to save $100 on the purchase of a Zona Plus device

Element Health Supply: Use code Lonevity when shopping at https://elementhealthsupply.com/discount/Longevity to save on your orders.

SiPhox: Visit http://SiPhoxhealth.com/nat and save on your test.

Find more from Kiran Krishnan & Just Thrive:

Website: https://justthrivehealth.com Instagram: https://www.instagram.com/justthrivehealth/

Find more from Nathalie:

YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ

Join Nat’s Membership Community: https://www.natniddam.com/bsp-community

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Website: www.NatNiddam.com

Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance

Key Take Aways:

Gut health significantly impacts overall well-being, including mental health, cognitive function, and systemic health.
Maintaining a balance of gut bacteria, which in turn supports metabolic, immune, and neurological health.
Consuming a diverse diet rich in fibers helps promote this diversity.
Consistent dietary and lifestyle changes are important for maintaining a healthy gut.
Prebiotics are as important as probiotics feed beneficial bacteria and support a healthy microbiome.