LONGEVITY with Nathalie Niddam

Dr. Bruce Hoffman discusses mast cell activation syndrome (MCAS), its triggers like environmental toxins and mold, and the impact on physical and mental health. Topics include electrolyte balance, understanding MCAS symptoms and diagnosis challenges, Ehler Danlos syndrome and its subcategories, autonomic regulation, mold exposure, importance of the Kennedy Krieger test, and prioritizing health and wellness.

In this podcast, they discuss the confusion and disagreement surrounding different dietary approaches, emphasizing the importance of finding a diet that works for each individual. They explore the idea that nutrition is personal and unique, sharing tips for adopting a new lifestyle and collecting data. They also explore the role of the microbiome in overall health and discuss the importance of baselines for weight loss. The hosts engage with the audience and seek feedback for future episodes.

Have you ever heard of heavy water?   In this episode of the Biohacking Superhuman Performance podcast, I chat with Victor Sagalovsky, Co-Founder and CEO of Litewater Scientific, about deuterium-depleted water. Deuterium is a naturally occurring isotope of hydrogen that has an extra neutron in its nucleus, making it twice as heavy as ordinary hydrogen, thus where it got its name of heavy water. Studies suggest that reducing deuterium levels in the body can have positive effects on various biological processes, such as improved cellular function, enhanced energy production, increased support of the immune system, and potential anti-aging properties.    Victor also shares how much deuterium we should have in our bodies, how long it takes to see results from drinking deuterium-depleted water, and who is most likely to experience the biggest shift in their health from intaking heavy water.   Victor Sagalovsky is the co-founder and CEO of Litewater Scientific, the first and only super deuterium-depleted light water, where he has dedicated himself to the research, development, and production of this rare water. Victor has researched and studied the benefits of deuterium-depleted water through his theory entitled Endogenous Radiation Damage Theory of Aging. It proposes that our biggest obstacle to longevity is the excess deuterium and other damaging isotopes on the planet and proper mitigation will radically extend our lifespans.      Thank you to our sponsors for making this episode possible:   Litewater : Use code NAT10 to save 10% at https://bit.ly/41BT7sR   Restoracell: Use code NAT25 at https://www.vitaliskincare.com/   Berkeley Life: Use code NIDDBL for 10% off at berkeleylife.com   LVLUP: Use code NAT10 to save 10% off at https://lvluphealth.com/   Find more from Nathalie:   YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance Instagram: https://www.instagram.com/nathalieniddam/ Website: NatNiddam.com Join Nat’s Membership Community: https://www.natniddam.com/bsp-community Work with Nat: Book Your 20-Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08   Find more from Victor Sagalovsky:    Website: https://www.drinklitewater.com/ Instagram: https://www.instagram.com/drinklitewater/   What we discuss:   02:16: What is deuterium-depleted water? 05:56: How do carbs affect deuterium levels in the body? 10:55: Who discovered the effect of deuterium? 17:16: What are the kinetics of deuterium water? 20:34: How long does it take to see results? 24:44: How does hydrogen interact with deuterium?  31:25: How does structured water compare to deuterium water? 35:25: Is Litewater structured? 36:38: How much deuterium should we have in our bodies? 43:51: Who would experience the biggest shift when intaking deuterium-depleted water? 56:35: Where to learn more about Victor and Litewater?   Key takeaways:   Deuterium is a naturally occurring isotope of hydrogen that has an extra neutron in its nucleus, making it twice as heavy as ordinary hydrogen, thus where it got its name of heavy water.    Deuterium-depleted water is considered to be a huge factor in why certain people get to live past 100 years old. Not only does it improve mitochondrial function, but it also helps reduced oxidative stress, enhance cellular repair, and regulate hormones that influence aging and lifespan.   Deuterium mainly affects mitochondrial function, which plays a crucial role in energy production by generating adenosine triphosphate (ATP). This is because deuterium has a larger mass compared to hydrogen, which can influence the rates of enzymatic reactions occurring in the mitochondria. High levels of deuterium in the mitochondria can also disrupt the balance of cellular redox reactions and potentially impact mitochondrial function.

What if your body could perform at superhuman levels using the power of science? The exploration of carbon 60's potential as a biohack for peak human performance presents an exciting frontier in health and wellness. This episode dives into the astounding world of Carbon 60 - a unique carbon allotrope that has the potential to push human performance to unprecedented heights.   Today I’m with Ian Mitchell, founder of Wizard Sciences, who created a world-class health and wellness research and development company. Our conversation dives into the remarkable properties of Carbon 60, investigating its role in reducing oxidative stress, increasing ATP production, detoxifying the body, inhibiting lipid peroxidation, and preventing rancidity. We delve into C60’s exciting emergence as a supplement, accompanied by Mitchell's groundbreaking innovations like Wizard Water, a hyper-oxygenated drink that has the potential in improving oxygenation and decreasing muscle fatigue. We also discuss the profound science behind waveform dynamics and quantum charging cells, as well as protocols to ensure carbon 60 is used beneficially and not as a detriment.    As a research scientist and pharmaceutical consultant, Ian is Chief Science Officer at Redbud Brands and at HigherDOSE. He is Chief Science Advisor at Leela Quantum and is Scientific Advisor at Satori Neuro. Ian is also Polymath in Residence at Ecliptic Capital.   Thank you to our sponsors for making this episode possible: Wizard Sciences: Visit wizardsciences.com. Use code NAT15 at checkout for 15% discount. Mitopure: Go to timelinenutrition.com/NAT10 and use code NAT10 to get 10% off your order. LMNT: Use Drinklmnt.com/NAT to get 8 free single serves with any order to try different flavors. Profound Health: Use code longevity15 to save 15% off your first order at https://profound-health.com/.   Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance Instagram: https://www.instagram.com/nathalieniddam/ Website: NatNiddam.com Join Nat’s Membership Community: https://www.natniddam.com/bsp-community Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08   Find more from Ian Mitchell: Website: https://wizardsciences.com/ Instagram: @wizardsciences What we discuss: (0:07:10) - Effects of C60 (0:17:05) - Overcoming Injury With Resilience and Gratitude (0:22:14) - Carbon 60 and Healing Potential (0:28:24) - Quantum Waveform Dynamics and Allergic Reactions (0:35:39) - Carbon 60 and Its Effects Discussion (0:40:24) - Carbon 60 and Performance Enhancement (0:49:56) - Benefits of Olympic and Neural RX (1:02:32) - Exploring Brain-Boosting Formulas (1:06:32) - Exploring Science, Improving Human Performance  

Ready to challenge the current beliefs about meat consumption? There are current narratives that have demonized meat, explicating the healing powers of grass-fed pasture-raised meats for both our bodies and the planet. Today we’re debunking myths and misconceptions about meat consumption and its environmental impact.   I’m joined by Autumn Smith, and we’re discussing the potential of regenerative farming techniques, compared to conventionally raised beef. We navigate through the arguments against beef consumption and Autumn sheds light on how regenerative farming could be scaled to meet the needs of a growing population. We also discuss the critical role of humane treatment of animals in our food choices and reflect on our obligation as omnivores to respect the natural cycle of life.   Autumn Smith is the co-founder of Wild Pastures and Paleovalley, a company dedicated to helping people get the essential nutrients they need without added sugars, grains, or other harmful ingredients. She holds a Master of Science in Holistic Nutrition and is a Functional Diagnostic Nutrition Practitioner. She is also a certified eating psychology coach by the Institute of the Psychology of Eating and Soil Advocacy and is a doctoral candidate. Thank you to our sponsors for making this episode possible: Paleovalley: Use the link paleovalley.com/nathalie for 15% off. Restoracell: Use code NAT25 at https://www.vitaliskincare.com/ Healthgevity: Visit https://healthgev.com and use code LONGEVITY   Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance Instagram: https://www.instagram.com/nathalieniddam/ Website: NatNiddam.com Join Nat’s Membership Community: https://www.natniddam.com/bsp-community Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08   Find more from Autumn Smith: Website: Paleovalley.com Instagram: @paleovalley  Link: paleovalley.com/promos/nathalie - 15% off (no code needed)   What we discuss: (0:08:00) - Regenerative agriculture compared to conventionally raised meat (0:13:00) - What is regenerative farming (0:15:36) - Misconception of livestock environmental impact (0:20:15) - Regenerative farming techniques for scale (0:25:13) - Arguments against consuming animal products  (0:28:00) - Narrative of consuming animal products (0:35:47) - How eating animal products impacts health (0:43:59) - Research of grain-fed beef, grass-fed beef, and plant-based meat, and their impact on human health. (0:48:10) - Nutrients in food (0:53:17) - Negatives of meat (0:57:41) - Beliefs and science of meat consumption (1:02:54) - Organ meats    Key Takeaways: Conventional meat production, which is largely based on factory farming, is not sustainable due to its environmental impacts. Regenerative agriculture, on the other hand, uses animals in a more sustainable way by working with nature rather than against it. This results in healthier soil, more nutrient-dense food, and the potential to sequester carbon. There is a common misconception that meat is a major cause of disease. However, the real dietary villains are sugar, carbohydrates, and processed foods. Animal products are our most nutrient-dense foods, but the quality and source of the meat you consume matters significantly. Grass-fed, pasture-raised meat has significant health benefits and is better for the environment than grain-fed, factory-farmed meat.  Traditional diets often incorporated organ meats, suggesting that they have long been recognized for their nutritional benefits. Consuming organ meats, such as heart, liver, kidney, and spleen, can be beneficial for their nutrient profile, which includes zinc, iron, B12, and vitamin A.  

Dr. Dale Bredesen discusses the prevention and potential reversal of Alzheimer's disease, and the role of the immune system. The podcast explores the changing approach to medicine and Alzheimer's, the brain's response to invasion, the importance of mitophagy, the APOE4 gene variant, and the effects of alcohol on the brain.

Can you imagine a world where you're not bound by the inevitability of aging? These days it seems as though there’s a never-ending pursuit of immortality, but it’s important to question the quality of life that extended lifespans might offer. The secret to a longer, happier life may not solely lie in age-reversing technologies and biohacking techniques, but rather in our experiences and connections with the world.   I’m joined by Dr. Christopher Shade, and we’re diving into the realm of biohacking, self-care, and the prospects of reversing and embracing aging. From nutrition and detoxification to stem cells and peptides, we discuss the plethora of tools at our disposal to reverse the aging process. We also cover the practical implications of integrating one's consciousness into a machine, and why self-care and taking responsibility for our emotional health is essential.    Dr. Christopher Shade, PhD, founder and CEO of Quicksilver Scientific®, specializes in the biological, environmental, and analytical chemistry of mercury in all its forms and their interactions with sulfur compounds, particularly glutathione and its enzyme system. Dr. Shade is regularly sought out to speak as an educator on the topics of mercury, environmental toxicities, neuroinflammation, immune dysregulation, and the human detoxification system in the United States and internationally. He has helped corporate executives, professional athletes, celebrities, children with autism, patients with chronic immune disorders and more. He strives to evolve the way the medical industry delivers care, and he is perpetually broadening the way the world understands health. Thank you to our sponsors for making this episode possible: QuickSilver Scientific: Use code NAT at https://glnk.io/zvxl/biohackingnat Restoracell: Use code NAT25 at https://www.vitaliskincare.com/ LMNT: Use Drinklmnt.com/NAT to get 8 free single serves with any order to try different flavors. Berkeley Life: Consumers may register and place an order using my code NIDDBL for 10% off at berkeleylife.com   Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance Instagram: https://www.instagram.com/nathalieniddam/ Website: NatNiddam.com Join Nat’s Membership Community: https://www.natniddam.com/bsp-community Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08   Find more from Dr. Christopher Shade: Website: quicksilverscientific.com Instagram: @dr.christophershade, @quicksilverscientific What we discuss: (0:00:04) - Reversing and embracing aging (0:09:44) - Benefits of biohacking and self-care (0:15:34) - Detoxification and chronic infections (0:22:30) - Bio reset (0:35:07) - Functional and integrative medicine (0:45:50) - Bio age reset and detox program (0:57:05) - The power of self-love and gratitude Key Takeaways: Taking 100% responsibility for our internal emotional life means being mindful of how we choose to respond to others. We don't necessarily have to get upset when someone says something negative to us, as our emotional reactions are our own responsibility. This also extends to taking 100% responsibility for our own personal growth and life journey, and being mindful of our words and actions towards others. Bile serves as the pathway for toxins to exit the liver and enter the gastrointestinal (GI) tract. However, stress, being in a sympathetic state, and estrogen dominance can block bile flow. This can lead to activation of glutamate receptors and hinder the prioritization of regenerative processes. It is easy to fall into an inflammatory state, inhibiting positive growth and contributing to weight gain. Toxins play a role in triggering and prolonging this inflammatory state, preventing us from entering a positive, regenerative state. There are a multitude of environmental toxins that we are exposed to, as well as our own biological waste, which can accumulate if our body's processes are not functioning properly.  

Whether you’re a professional athlete or someone who just wants to maintain muscle mass as you get older, mitophagy is a process we should all be focusing on. Prioritizing strategies that enhance mitophagy and promote muscle health can significantly contribute to a healthier and longer life. But what exactly can we do to promote mitophagy? Luckily, my guest today is an expert in the science of mitochondrial activation, and he’s sharing insights on the supplement that you need in your longevity routine.   I’m joined by Dr. Anurag Singh, and we’re diving into the realm of mitochondrial activation and its impact on muscle performance and health. We also shed light on the role of immunity in a healthy, long life, focusing on how mitochondrial health can rev up our immune systems. Dr. Singh also shares his insights on how mitochondrial health can influence skin health and reverse sun damage, and the development of topical formulations that can improve mitochondrial health in the skin.   Dr. Anurag Singh is the Chief Medical Officer at Timeline Nutrition.    Thank you to our sponsors for making this episode possible:   Timeline is offering 10% off your first order of Mitopure. Go to timelinenutrition.com/NAT10 and use code NAT10 to get 10% off your order.   Paleovalley: Try my go-to snacks, the Paleovalley beef sticks. Head to paleovalley.com/nathalie to save 15% on your order. Berkeley Life: Consumers may register and place an order using my code NIDDBL for 10% off at berkeleylife.com Profound Health: Use code longevity15 to save 15% off your first order at https://profound-health.com/   Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance Instagram: https://www.instagram.com/nathalieniddam/ Website: NatNiddam.com Join Nat’s Membership Community: https://www.natniddam.com/bsp-community Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08   Find more from Dr. Anurag Singh: Website: https://www.timelinenutrition.com/ Instagram: @timelinenutrition   What we discuss: (0:00:00) - Mitochondrial activation and muscle performance (0:12:13) - Revving up immune health through mitochondria (0:15:24) - Mitochondrial health and immune function studies  (0:21:06) - The benefits of high-dose vitamin c  (0:26:20) - Skin aging and mitochondrial health (0:27:53) - Topical formulation and skin health  (0:33:22) - Supplement industry quality and safety   Key Takeaways: The muscle is the most metabolically active organ in our body. It both produces and consumes the most energy currency, ATP. This is because even small movements like getting up from a chair or climbing stairs require a significant amount of energy. Activating mitophagy, the process by which damaged or dysfunctional mitochondria are selectively removed, has been shown to have significant positive effects on muscle performance. By selectively eliminating these damaged components, it allows for the generation of new and healthy mitochondria, thus enhancing muscle function.  Maintaining a healthy immune system can directly impact our overall health and lifespan. Immune cells, just like muscle, brain, and heart cells, contain numerous mitochondria. These mitochondria play a crucial role in supporting the high energy demands of immune cells.  

Did you know that hormones play a pivotal role in directing the course of your health throughout your lifetime? From physical growth and development to emotional well-being and reproductive health, these chemical messengers are vital for our overall well-being. Understanding how hormones function and seeking appropriate medical guidance can help us navigate through the various stages of life while maintaining hormonal balance.   Dr. Felice Gersh joins me as we take a closer look at the different types of estrogens, their individual impacts on the body, and the importance of understanding their nuances for overall health. We also discuss how reproduction is the prime directive of life and how hormones act as 'hormonal glue' to enable reproductive success. Plus, we dive into some of the benefits and complexities of Hormone Replacement Therapy (HRT), including when to start and the potential risks associated with it.   Dr. Felice Gersh is board-certified in both OB/GYN and Integrative Medicine. She is the founder and Medical Director of the Integrative Medical Group of Irvine. Always passionate about learning and education, she taught obstetrics and gynecology at Keck USC School of Medicine for 12 years as an Assistant Clinical Professor. Dr. Gersh now serves as an Affiliate Faculty Member at the Fellowship in Integrative Medicine, through the University of Arizona School of Medicine, where she lectures and regularly grades the case presentations written by the Fellowship students for their final exams. Dr. Gersh is a globally recognized expert on a wide range of female and integrative health topics.      Thank you to our sponsors for making this episode possible: Restoracell: Use code NAT25 at https://www.vitaliskincare.com/ Troscriptions: Use code NAT10 at https://troscriptions.com/ LVLUP: Use code NAT10 to save 10% off at https://lvluphealth.com/ Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance Instagram: https://www.instagram.com/nathalieniddam/ Website: NatNiddam.com Join Nat’s Membership Community: https://www.natniddam.com/bsp-community Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08   Find more from Dr. Felice Gersh: Website: https://integrativemgi.com/ Instagram: @dr.felicegersh    What we discuss: (0:00:03) - The importance of women's hormones (0:16:18) - Understanding the different types of estrogens (0:20:05) - The effects of hormone therapy (0:27:25) - Exploring hormone replacement and natural alternatives (0:34:47) - The benefits of cyclical hormone therapy (0:45:23) - Benefits of vaginal estrogen and hormone replacement therapy (0:53:58) - The complexities of hormone replacement therapy (1:06:24) - Testing hormones for women   Key Takeaways: Osteoporosis is a condition where bone loss occurs gradually over time. However, in the first few years after menopause, there is a significant acceleration of bone loss. If individuals have not proactively taken measures to mitigate this rapid loss, their condition could worsen. This pattern can be applied to other organ systems as well, where starting the menopausal transition in a good state overall leads to better outcomes. It is essential to understand that the testosterone produced by the ovaries plays a crucial role in promoting overall health and well-being in women. The ovaries have the ability to produce testosterone indefinitely in a different part of the ovary, even after the eggs are depleted. This explains why removing the ovaries, even in post-menopausal years when they are no longer producing estrogen or progesterone, can negatively impact a woman's health and increase mortality.  The prime directive of life is reproduction, and humans are the only species on the planet that actively work towards controlling their reproductive fate. Unlike animals in the wild, humans have the capability to make deliberate decisions about when to have children. Setting aside the aspect of choice, it is crucial to understand that the female body is inherently optimized and designed for fertility and reproduction.  

Imagine a world where you could restore balance to your body, combat chronic diseases, and improve health trajectories through a deep understanding of your microbiome. That's exactly what we're exploring today with businesswoman-turned-research-scientist Martha Carlin, who embarked on this incredible journey after her husband was diagnosed with Parkinson's at a young age. Her captivating research has led to groundbreaking connections between the microbiome and the onset of chronic diseases such as Parkinson's, and she believes that restoring the microbiome could make a substantial difference in our overall health.   We're diving into the complex world of microbial peptides, toxins, and pathogens, particularly their influence on the body's immune system. We also discuss the potential links between copper, iron, and neurological diseases, and how copper's role in iron regulation could have far-reaching implications. Martha's fascinating insights also shed light on the connection between glyphosate, food contamination, and how it could be affecting our health.   Martha Carlin is a Citizen Scientist, systems thinker, wife of Parkinson’s warrior, John Carlin, and founder of The BioCollective, a microbiome company expanding the reach of science. Since John’s diagnosis in 2002, Martha began learning the science of agriculture, nutrition, environment, infectious disease, Parkinson’s pathology and much more. In 2014, when the first research was published showing a connection between the gut bacteria and the two phenotypes of Parkinson’s, Martha quit her former career as a business turnaround expert and founded The BioCollective to accelerate the discovery of the impact of gut health on all human health, including Parkinson’s.       Thank you to our sponsors for making this episode possible: Learn more and shop at biotiquest.com + use code NAT10 for a 10% off discount BiOptimizers: For Sleep Breakthrough use code BIONAT10 at checkout to save 10% at sleepbreakthrough.com/bionat Berkeley Life: Consumers may register and place an order using my code NIDDBL for 10% off at berkeleylife.com LVLUP: Use code NAT10 to save 10% off at https://lvluphealth.com/ Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance Instagram: https://www.instagram.com/nathalieniddam/ Website: NatNiddam.com Join Nat’s Membership Community: https://www.natniddam.com/bsp-community Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08   Find more from Martha Carlin: Website: https://biotiquest.com/ Facebook: https://www.facebook.com/BiotiQuest Twitter: https://twitter.com/BiotiQuest Instagram: https://www.instagram.com/biotiquest/ What we discuss: (0:00:04) - Parkinson's and the microbiome link (0:08:59) - Sleep disruption in neurodegenerative diseases (0:13:29) - Toxins, pathogens, and the Parkinson's microbiome (0:24:35) - Copper's role in iron regulation (0:42:49) - Glyphosate contamination and organic farming (0:47:59) - Parkinson's symptoms improvement through diet (0:54:30) - Red light therapy and microbiome health (1:04:33) - Improving health and restoring balance Key Takeaways: In some ways, the process of consuming food can be seen as a way of receiving information from the food itself. When we eat, our bodies extract various nutrients and compounds from the food, which contain valuable information that gets transmitted to our system. The gut plays a crucial role in this process, serving as the interface or channel for communication between the food and our cells. Heat Shock Protein (HSP) 65 is produced by certain pathogens or microbes, and it is not beneficial to us. On the other hand, HSP 60 and Alpha-b Crystallin play important roles in maintaining our health. However, the presence of the nefarious alpha crystalline and HSP 65 confuses our body, causing it to mistakenly attack our own beneficial proteins.  Higher iron levels may increase the likelihood of hosting more pathogens, and the immune system responds by attempting to sequester the iron and prevent pathogen access. However, this defensive strategy often involves storing iron in the body's tissues, which subsequently leads to inflammation.