LONGEVITY with Nathalie Niddam

If you’ve ever suffered from joint pain or inflammation, you know just how much it can take a toll on your quality of life. Whether you’re an athlete suffering from a sports-related injury or someone who’s noticed more and more aches and pains as you’ve gotten older, finding a solution to joint pain can seem almost impossible. Luckily, my guest today is here to talk about the light therapy device that ​​is a game-changer for pain management.   I’m joined by Forrest Smith, the CEO of Kineon Labs, to dive into the benefits of using light therapy to reduce joint pain. We discuss how localized inflammation has the potential to spread through the body if not addressed, and how red light can target specific reservoirs. We also talk about the balance of cartilage regrowth and degradation, and the benefits of Kineon Lab’s MOVE+ Pro.   Forrest Smith has a 20-year history of building successful startups in tech hardware. He is an entrepreneurial optimist and passionate about health, wellness, and advancing technology to help others. Forrest speaks, reads, and writes fluent Chinese and has spent his adult life building amazing products around innovative supply chains. He grew up playing competitive sports in Atlanta and regularly participates in rugby matches and trains CrossFit, which ultimately led him to develop Kineon Lab’s Move+: a modular, targeted laser therapy device for neuromuscular pain and inflammation. Thank you to our sponsors for making this episode possible: Use code NAT10 to save 10% at https://kineon.io/ Paleo Valley: Use discount code paleovalley.com/natalie LMNT: Use Drinklmnt.com/NAT to get 8 free single serves with any order to try different flavors. Mitopure: Use code NAT10 for 10% your order at https://www.timelinenutrition.com/shop/nutrition Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance Instagram: https://www.instagram.com/nathalieniddam/ Website: NatNiddam.com Join Nat’s Membership Community: https://www.natniddam.com/bsp-community Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08   Find more from Forrest Smith: Website:  https://kineon.io/ Instagram: @kineon_labs Facebook Group: https://www.facebook.com/groups/302581657766248   What we discuss: [00:00:50] Kineon Labs’ approach to helping people solve their joint pain  [00:04:23] The benefits of red light therapy  [00:08:34] How does red light target specific reservoirs? [00:12:37] The balance of cartilage regrowth and degradation [00:18:10] Why it’s important to address localized inflammation [00:25:39] Treating the underlying mechanisms of what's causing pain  [00:35:05] The different types of protocols the MOVE+ Pro offers [00:39:58] Who can benefit from MOVE+ Pro [00:46:05] Future products coming to Kineon Labs [00:56:31] How surgery can lead to trauma in the tissue [00:59:46] Can MOVE+ Pro be used in multiple areas during a session? Key Takeaways: Cartilage, the slow-growing but ever-evolving tissue in our bodies, plays a crucial role in supporting our joints and bones. Similar to bones, cartilage grows gradually and follows a unique process involving specialized cells called chondroblasts. These chondroblasts can be stimulated to proliferate faster through the application of infrared and red light treatment. Locally generated inflammation damages more than just the regional delivery of blood- it also damages the blood vessel tissue throughout the rest of your body, which is a main cause of long term cardiovascular disease. By addressing the localized inflammation, you're preventing it from spreading to the rest of the body. Infrared light has the ability to interact with proteins like hemoglobin, cytochrome C oxidase, and other heme proteins in the mitochondria. By targeting these proteins with infrared light, it reduces the affinity of nitric oxide for their binding sites, enabling them to access more oxygen. This interaction can potentially enhance oxygen delivery in the body.  

Our skin was designed to function as a barrier to protect our bodies from environmental stressors and pathogens, but unfortunately, our skin barrier is one of the main factors that is compromised as we age. Many of us are constantly looking for the next best thing to slow down and possibly even reverse these signs of skin aging, and my guest today is here to explain why focusing on products that work on the molecular level is the key to healthy aging.   I’m joined by Carolina Oliveira, the CEO and co-founder of OneSkin, to discuss everything you need to know about healthy aging in the skin. We cover cellular senescence, biological age, systemic inflammation, and the research being done at OneSkin to quantify these things. We also talk about some of the other factors that have an impact on skin health, and of course dive into the first peptide developed to reverse skin aging at the molecular level: OS-O1.   Carolina Oliveira is the CEO and co-founder of OneSkin. She holds a Ph.D. in stem cell biology and tissue engineering, is a co-inventor of 5 patents and co-author of numerous scientific publications. She relocated from Brazil to Silicon Valley in 2016 to found OneSkin, a fast-growing longevity company developing products to promote skin health by targeting aging at the molecular level. Carolina is an alumnus of IndieBio, the world's largest biotech accelerator and has been an active voice in the longevity field, pioneering age reversal skin research with OneSkin.  Thank you to our sponsors for making this episode possible: OneSkin: Use code SUPERHUMAN15 at https://www.oneskin.co/ BiOptimizers: For Sleep Breakthrough use code BIONAT10 at checkout to save 10% at sleepbreakthrough.com/bionat Berkeley Life: Consumers may register and place an order using my code NIDDBL for 10% off at berkeleylife.com Neurohacker Collective: https://bit.ly/QNHNat and use code NN15 Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance Instagram: https://www.instagram.com/nathalieniddam/ Website: NatNiddam.com Join Nat’s Membership Community: https://www.natniddam.com/bsp-community Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08   Find more from Carolina Oliveira: Website: oneskin.co   What we discuss: [00:03:24] The skin barrier and why our skin becomes more fragile as we age [00:08:30] Does nutrition have a big impact on skin health? [00:16:05] The skin’s biological age clock [00:22:48] Does cellular senescence affect skin elasticity? [00:28:07] Ingredients to avoid when looking for skincare  [00:35:37] How long does it take to see results from OneSkin products?  [00:43:22] How OneSkin products can potentially lower systemic inflammation [00:50:09] The different concentration of OS-O1 in each product Key Takeaways: Cellular senescence is a process in which cells stop dividing after reaching their replication limit of around 50 times. These cells have accumulated various mutations that can lead to cancer if they continue to divide. Therefore, cellular senescence functions as a protective mechanism for the body. However, these senescent cells also secrete inflammatory signals that can cause neighboring cells to age faster. When it comes to choosing skincare products, it is important to pay attention to the ingredients list. Some ingredients, like parabens and fragrance, can cause irritation or harm to the skin. Parabens are preservatives that have been linked to endocrine disruption, while fragrance can cause allergic reactions or sensitivity.  Websites like EWG can be a helpful resource for checking the safety of skincare products and their ingredients.  Advanced Glycation End-products (AGEs) are naturally occurring compounds that are formed when glucose reacts with proteins in the body. The accumulation of AGEs in the skin leads to the degradation of collagen and elastin fibers, which are responsible for keeping the skin firm and elastic.  

The rise of ketamine therapy has been a hot topic in the world of medicine. For decades, ketamine has been used as an anesthetic in surgery and as a pain reliever. However, in recent years, it has gained attention as a potential treatment for depression, anxiety, PTSD, and other mental health disorders. As the use of ketamine therapy continues to grow, more and more patients are finding relief from their mental health issues and an improved overall quality of life.   I’m joined by Caleb Greer, and we’re diving into the world of ketamine therapy. We cover how exactly ketamine works and what people feel when using ketamine, plus how it can be used as an effective treatment for mental health issues. We also discuss the long-term effects of ketamine, how it can help inhibit pain, and the difference between ketamine and other well-known psychedelics.    Caleb Greer is the founder of Dasein Health. In pursuit of becoming a well-rounded practitioner, Caleb studies all facets of human physiology and applies his understanding to the realms of mental and physical health. In his short time in practice, Caleb has helped over a thousand individuals reintroduce and optimize function through his multidisciplinary approach that integrates neurology, psychology, epigenetics, nutrition, biomechanics, and medicine.   Thank you to our sponsors for making this episode possible: Mitopure: Use code NAT10 for 10% your order at https://www.timelinenutrition.com/shop/nutrition Sensate: Use code NAT at https://buy.getsensate.com Profound Health: Use code longevity15 to save 15% off your first order at https://profound-health.com/ Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance Instagram: https://www.instagram.com/nathalieniddam/ Website: NatNiddam.com Join Nat’s Membership Community: https://www.natniddam.com/bsp-community Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08   Find more from Caleb Greer: Website: https://www.daseinhealth.org/, https://daseinhealth.substack.com/ Patreon: https://www.patreon.com/DaseinHealth Instagram: @daseinhealth What we discuss: [00:02:01] The idea that drugs can be utilized for therapeutic purposes  [00:08:47] What do people feel when using ketamine? [00:14:32] Using ketamine for chronic pain  [00:23:04] Ketamine can help people to see the fundamental sense of belonging [00:31:20] Ketamine therapy can speed up the acknowledgment of changes [00:39:04] Is ketamine addictive? [00:51:52] How to access ketamine therapy Key Takeaways: Ketamine is a type of drug that is known to be dissociative. This means that it can cause a person to feel disconnected from the outside world, as if they are in their own world. Ketamine can also cause a person to experience a highly introspective state, where they are able to reflect on their thoughts and emotions in a deeper way than usual. Ketamine is known to be anti-nociceptive, which means that it has the ability to block the signals that are responsible for registering pain in the brain. This means that ketamine can be used to effectively manage pain in patients who are experiencing acute or chronic pain. Ketamine has been found to be particularly effective in addressing emotional dysregulation, which is a common symptom of various mental health conditions. By acknowledging and addressing this symptom, ketamine therapy can help people gain a better understanding of their emotions and learn how to regulate them more effectively.  

Did you know that by the age of 40-50, people have anywhere between 10 to 30% senescent cells in their tissues? Senescent cells are one of the hallmarks of aging, and can disrupt physiology throughout the body. Cellular senescence is the process by which cells permanently stop dividing but do not die off. These senescent cells linger inside the body and accumulate over time, affecting the healthy function of tissues and organs as we age.   I’m joined by Dr. Nick Bitz, and we’re diving into everything you need to know about senescent cells and cellular senescence. We discuss why our bodies need some senescent cells, and some of the lifestyle changes we can make to support the body's ability to clear senescent cells. Plus, we answer the question: How young is too young to be worried about your senescent cells?    Dr. Nick Bitz is a Naturopathic Physician that specializes in Ayurvedic medicine. He is a leading voice in the natural products industry and currently serves as Senior VP of Product Development at Neurohacker Collective. His areas of expertise include nootropics, anti-aging medicine, biohacking, herbology, nutrition and dietary supplements. Thank you to our sponsors for making this episode possible: Add Neurohacker’s Senolytic to your longevity routine by using code NATHALIE at neurohacker.com/nathalie  LMNT: Use Drinklmnt.com/NAT to get 8 free single serves with any order to try different flavors. Profound Health: Use code longevity15 to save 15% off your first order at https://profound-health.com/ Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance Instagram: https://www.instagram.com/nathalieniddam/ Website: NatNiddam.com Join Nat’s Membership Community: https://www.natniddam.com/bsp-community Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08   Find more from Dr. Nick Bitz: Website: https://neurohacker.com/ Instagram: https://www.instagram.com/neurohacker/ Facebook: https://www.facebook.com/neurohackercollective LinkedIn: https://www.linkedin.com/in/nick-bitz-283a03b/   What we discuss: [00:04:18] Why our bodies need some senescent cells  [00:11:34] How young is too young to be worried about your senescent cells?  [00:19:18] Lifestyle changes to support the body's ability to clear senescent cells  [00:30:43] Optimizing health throughout the entire body [00:40:53] Targeting different communities of senescent cells  [00:47:21] The importance of intermittent fasting Key Takeaways: 40 years old is the age where it is especially important to start taking steps to prevent senescent cells from accumulating in the body and causing age-related diseases, inflammation, weakened immune system, and cell damage.  Autophagy is the process by which cells break down and recycle their own components. Promoting autophagy can help reduce the formation of senescent cells, as it can help the body remove damaged cells and other debris that can accumulate and lead to cell senescence.  Senescent cells can accumulate in different tissues and organs, such as the skin, heart, and lungs, and can disrupt normal function. Therefore, it is important to address senescent cells in all tissues and organs to ensure optimal health.  

Over the past 20 years, there’s been a transition in the discussion around mental health. Now more than ever, there’s been a heavy focus on stress, anxiety and the impact they can have on our overall health. However, the ability for people to engage with techniques such as mindful breathing and meditation has also decreased over the years.   I’m joined by Stefan Chmelik, co-founder and inventor of Sensate, to discuss why it’s important to focus on regulating our nervous system, and how embracing discomfort and taking risks is key to transformation and development. We also dive into the technology behind Sensate, the benefits of using Sensate, and the different use cases. If you’re someone who is looking for a way to regulate your nervous system and improve the amount of quality sleep you’re getting each night, you’ll want to tune into our conversation.   Stefan is the inventor of the Sensate technology, a lifelong meditator and founder of London Harley Street’s New Medicine Group. Stefan is a technology innovator and physician with 30 years of clinical experience, working with tens of thousands of patients experiencing stress and anxiety. He is now entirely devoted to leveraging his significant and unique experience towards achieving maximum impact for Sensate as the ideal consumer solution. Thank you to our sponsors for making this episode possible: Sensate: Save 10% at getsensate.com/NAT Primeadine: Use promo code BIONAT15 to save 15% on your first order at https://oxfordhealthspan.com/products/best-spermidine-supplement Berkeley Life: Consumers may register and place an order using my code NIDDBL for 10% off at berkeleylife.com LVLUP: Use code NAT10 to save 10% at https://lvluphealth.com/ Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance Instagram: https://www.instagram.com/nathalieniddam/ Website: NatNiddam.com Join Nat’s Membership Community: https://www.natniddam.com/bsp-community Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08   Find more from Stefan Chmelik: Website: https://www.getsensate.com Instagram: https://www.instagram.com/mysensate/ LinkedIn: https://www.linkedin.com/company/bioself-technology-ltd/ What we discuss: [00:02:03] Stefan’s background in natural medicine and philosophy [00:05:25] Why people stopped being able to meditate and do breathing exercises  [00:11:17] Stress, trauma, and PTSD  [00:17:29] Transformation and development is only possible outside of your comfort zone  [00:26:23] How society predisposes us towards overwhelming feelings  [00:33:09] The importance of regulating HRV  [00:45:00] Why it’s important to be adaptable and flexible [00:51:38] The link between mental health and nature [00:58:08] How Sensate works to improve the quality of your sleep  [01:07:07] The different use applications of Sensate Key Takeaways: The autonomic nervous system is responsible for regulating automatic bodily functions such as heartbeat, digestion, and respiration. It is deeply wired into our cells, body, and connective tissues, ensuring that all these functions happen without us being consciously aware of them. Embracing discomfort and taking risks is key to transformation and development. By stepping outside of our comfort zone and exposing ourselves to “good stress”, we can help build resilience and adaptability.  Humans are fundamentally tied to nature, and this is reflected in our nurture and survival responses. The human response to nature is complex and multifaceted, incorporating both physical and emotional elements. Our bodies are designed to respond to various environmental stimuli, both positive and negative, in order to ensure our survival.  

Did you know you can take CBD with your morning coffee?   In this episode of the Biohacking Superhuman Podcast, I chat with Adam Wenguer about the endocannabinoid system, which is a biological system composed of endocannabinoids, neurotransmitters, cannabinoid receptors, and receptor proteins.    Adam also shares the benefits of taking CBD both in the morning and the evening. While most of us are aware of the benefits we get from taking CBD to get into a parasympathetic state for better sleep, it works wonderfully to help enhance your focus and cognitive function in the morning.   Adam Wenguer is the founder and CEO of Element Health, producer of the most potent full-spectrum CBD on the market. He has a vast knowledge of the medicinal use of CBD/cannabinoids for human optimization and is an expert on the Endocannabinoid system. With a background in applied physiology, kinesiology, and human performance, Adam has over 20 years of experience working with professional athletes, company executives, and other high performers seeking to maximize their physical and mental capabilities.      Thank you to our sponsors for making this episode possible:   To Purchase any products from Element Health use code NAT15 to save 15% at https://elementhealthsupply.com/   Use code NAT10 for 10% off your order at https://www.timelinenutrition.com/shop/nutrition.   Go to www.DrinkLMNT.com/NAT to get 8 FREE single-serving packets with your order.   Go to https://oxfordhealthspan.com/en-ca and use code BIONAT15 for a discount.     Find more about Nathalie:   YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance Instagram: https://www.instagram.com/nathalieniddam/ Website: NatNiddam.com Join Nat’s Membership Community: https://www.natniddam.com/bsp-community Learn more about the 2023 Women’s Longevity & Resilience Retreat: https://www.natniddam.com/longevity-resilience     Find more from Adam:   Website: Use code NAT15 to save at https://elementhealthsupply.com/ Instagram: https://www.instagram.com/elementhealth/      What we discuss:   00:00:46: About Adam’s addiction journey 00:08:16: What is the endocannabinoid system?  00:13:18: What is CBD? 00:14:28: How does CBD reduce inflammation? 00:17:42: Why aren’t we in tune with our natural state anymore? 00:19:22: What should people look for in CBD products? 00:25:25: What is the beauty of full spectrum CBD? 00:30:09: What’s the issue with CBD gummies? 00:32:31: Can CBD be used in the morning? 00:34:00: How can CBD help at night? 00:35:15: Can you use less CBD and still get the same effect? 00:41:52: How does topical CBD help with inflammation? 00:48:23: What type of supplements should you avoid stacking with CBD? 00:55:03: What does Adam think of biohacking? 01:00:09: How does your personality impact your healing ability?     Key Takeaways:   We all know that less is more, and that couldn’t be more true when it comes to CBD. The goal with CBD is not to infinitely increase your dosage, but to reach a point where you need less of it. See, CBD has a thing called reverse tolerance where over time you you will need less of it to feel the same great results. This is due to CBD not directly binding to the receptors in the ECS. Instead, CBD is involved in communicating how to regulate various responses in the body. So once you’ve reached a peak in the optimization of whatever it is you’re trying to improve with CBD, then your body may slowly need less of that CBD to keep up the same good work.   Newsflash: CBD can be used all day long — and not only as a sedative at night. The key to reaping most of its benefits is to take the right dose at the right time, depending on the effect you want to have. So if you want to feel focused without the jitters often associated with caffeine, a small amount of CBD in the morning should help. But if you want to slip into a parasympathetic state, then taking CBD is the way to go.   The quality of the CBD you intake is just as important - if not more - than the dosage you take in. You need to do your research to find out what the farming, manufacturing, and overall commercialization process is like for the CBD brands you buy from. You need to be intentional about what you put in your body.

Do you feel like your sex life took a hit as you grew older?   In this episode of the Biohacking Superhuman Podcast, I chat with Susan Bratton about sexual biohacking. Most women tend to let their sex lives die off as they grow older, especially if their body changes in ways where sex just doesn’t happen to feel the same way that it used to. From vaginal dryness to difficulty achieving orgasms, Susan talks about the different sexual rejuvenation treatments and protocols women can try out so that they can continue to enjoy intimacy with their partners even as their bodies change over time.   We also chat about the importance of cultivating intimacy with a partner that you have been with for a long time. Susan shares her sex bucket list, among other tools, and explains how this tool can help light up that spark that may have been dormant between you and your partner for a while.    Susan Bratton is an Intimacy Wellness Expert, Sexual Bio-Hacker, and self-proclaimed “Orgasmanaut”, who is a champion and advocate for all those who desire lifelong intimacy and passion. She’s a best-selling author and publisher of 44 books and programs including Sexual Soulmates, Relationship Magic, Revive Her Drive, Ravish Him, Steamy Sex Ed™, The Passion Patch, Hormone Balancing, and Hot To Trot.      Thank you to our sponsors for making this episode possible:   Use code NAT to get 10% off Sensate now by heading over to getsensate.com   Use my practitioner code NIDDBL while registering at berkeleylife.com to get 10% off your first order.   Use code NAT25 to get 25% off Restoracell by heading over to https://www.restoracell.com     Find more from Nathalie:   YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance Instagram: https://www.instagram.com/nathalieniddam/ Website: NatNiddam.com Join Nat’s Membership Community: https://www.natniddam.com/bsp-community Learn more about the 2023 Women’s Longevity & Resilience Retreat: https://www.natniddam.com/longevity-resilience   Find more from Susan:   Website: https://betterlover.com/ Sex Life Bucket List: https://personallifemedia.com/sexlifebucketlist/ Instagram: https://www.instagram.com/susanbratton/   What we discuss:   00:02:24: Is sex good for you? 00:07:16: What does Susan think of sexual biohacking? 00:11:34: What is the difference between intimacy and sex? 00:22:17: Is the sex bucket list only for couples? 00:26:05: Why does it take longer for women to be ready to go? 00:33:30: Why do women experience vaginal dryness? 00:40:10: What sexual rejuvenation treatments does Susan recommend? 00:44:30: How can O shots help? 00:48:35: What is Orgasmic Cross-Training? 00:52:14: Where to learn more about Susan?   Key Takeaways:   One of the most common complaints women make once they reach menopause is that nothing feels good when it comes to love-making. The reason? They just can’t get aroused like they used to. Given that your vagina is a muscle and not a gland, it can’t lubricate itself without blood flow. Your vaginal tissue requires blood flow to seep through the layers of its tissue to wet the lining. But over time, as women reach menopause, the tissue thins out and tends to dry up. Thus, the importance of doing the work to bring blood flow back to your pelvic bowl - especially as you get older.   The #1 reason why women don’t enjoy sex is that they’re engaging in intercourse BEFORE their bodies are properly prepared for it! See, men tend to be aroused very quickly and are ready for intercourse within a few minutes of foreplay. On the other hand, women need an average of 20 to 30 minutes of consistent stimulation to be fully aroused. As a result, this makes sex less enjoyable as women engage in intercourse BEFORE enough time has gone by to ensure adequate blood flow has made its way toward their vaginal tissue - which would properly lubricate their vagina. And as women get older and the vaginal tissue thins out, it takes even more time to get aroused - making intercourse more painful than it used to be if they rush it.   Most women have been having sex like a dude most of their lives if not all of their lives. While it's something that women don’t realize early on in their sex life, it becomes a lot more apparent after menopause when their bodies change. 

Would you want to know when you are going to die?   In this episode of the Biohacking Superhuman Performance podcast, I chat with Hannah Went, Director of Operations at TruDiagnostic, about the stories certain biomarkers can tell about our present health and our future health. From predictors of lifespan to predictors of diseases, there is a large array of biomarkers we can target to help identify a patient’s biological age.    Hannah also shares what lifestyle changes someone can implement to increase their longevity and reverse the clock on their biological age so that it either equals or underpasses a person’s chronological age. From limiting alcohol consumption to caloric restriction, there is a multitude of lifestyle changes one can make to increase their lifespan.    Hannah Went has a lifelong passion for longevity and breakthrough, disruptive technologies that drive radical improvement to the human condition. She attended the University of Kentucky and graduated with a degree in Biology. After graduation, she worked for the International Peptide Society as their Director of Research and Content. Through work in the integrative medicine industry, Hannah saw an opportunity for methylation-based age diagnostics and started TruDiagnostics in 2020. TruDiagnostic is a company focusing on methylation array-based diagnostics for life extension and preventive healthcare serving functional medicine providers.      Thank you to our sponsors for making this episode possible:   Mitopure: Use code NAT10 for 10% off your order at https://www.timelinenutrition.com/shop/nutrition.   LMNT: Use Drinklmnt.com/NAT to get 8 free single serves with any order to try different flavors.   Profound Health: For Oral and Synthetic Bioregulators shipped worldwide as well as cutting edge anti-aging supplements use Profound-Health.com and discount code Longevity15 to save 15% off your first order     Find more from Nathalie:   YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance Instagram: https://www.instagram.com/nathalieniddam/ Website: NatNiddam.com Join Nat’s Membership Community: https://www.natniddam.com/bsp-community 2023 Women’s Longevity & Resilience Retreat : Learn More https://www.natniddam.com/longevity-resilience     Find more from Hannah:   Website: everythingepigenetics.com and trudiagnostic.com use code longevity12 for a discount Instagram: https://www.instagram.com/everythingepigenetics and https://www.instagram.com/trudiagnosticofficial      What we discuss:   02:29: What do all of these biomarker tests do? 06:14: What is an R-value? 09:24: What are first-generation clocks looking at? 13:22: What values do the second generation of clocks look at? 14:11: Is the GrimAge indicator an accurate predictor of lifespan? 17:03: What are the different metabolomic and proteomic approaches to biomarkers? 21:43: Why are third-generation clocks better than the precedent ones? 22:43: What can accelerate a person’s biological age? 27:57: Can exercise age you? 28:54: What does telomeres length mean about your health? 34:18: Against what population are your biomarkers usually compared? 36:40: What have the latest clinical studies found? 40:25: In which cases would your clock stay consistent over the years? 43:44: Can we determine which areas in our bodies are aging faster? 47:00: Can caloric restriction reverse biological aging? 52:01: What is the quicksilver protocol? 54:47: How often should you do a TruDiagnostic test? 56:03: What are the top lifestyle hacks to slow chronological aging? 57:30: Which supplements should you take? 58:50: Where to learn more about Hannah     Key takeaways:   Three different types of clocks examine biomarkers in terms of longevity: first-generation clocks, second-generation clocks, and third-generation clocks. They all examine different values that are indicative of longevity. Right now, the most precise clock is the third-generation clock as it is trained on direct biomarkers of health and disease, such as grip strength in people, aging-related brain shrinkage, dental health, lung function, and more.   Most of us have a biological age that is more advanced than our chronological age. While some factors influencing this premature aging can’t be changed, our biological age is heavily influenced by our lifestyle. Alcohol consumption, tobacco usage, sleeping patterns, stress management, and exercise are some of the few lifestyle aspects that can reduce our lifespan.

Did you know that stem cell therapy can be used as a preventative measure?    In this episode of the Biohacking Superhuman Performance podcast, I chat with Joy Kong, MD, about stem cell therapy. Stem cell therapy is a medical procedure that involves the use of stem cells to prevent, and address various diseases and conditions. Stem cells are unique cells that can differentiate into different types of cells in the body and can also self-renew to produce more stem cells.   Dr. Kong explains the different sources of stem cells they can pull from, such as the bone marrow, the fat tissue, and even from birth tissues. Depending on where the cells are sourced from, each source of stem cells has its advantages and disadvantages. We also chat about how stem cells differentiate from exosomes, the future of stem cell therapy, and what the research is saying about stem cell therapy for autism.   Joy Kong, M.D. is a UCLA-trained, triple-board-certified physician. She is the president of Uplyft Longevity Center in Los Angeles, California, where she specializes in stem cell therapy, and ketamine therapy, as well as a wide range of therapeutic modalities to improve patients’ overall health by enhancing their body’s innate regenerative potentials. Dr. Kong is the founder of the American Academy of Integrative Cell Therapy (www.aaict.org), where she provides training to physicians on stem cell therapy. Dr. Kong also conducts clinical research on stem cell therapy and is a published author in scientific journals.      Thank you to our sponsors for making this episode possible:   CharaOmni: Visit charaomni.com and try out their Stem Cell Face Cream and use code NAT10 for a 10% off your purchase   Berkeley Life: Consumers may register and place an order using my code NIDDBL for 10% off at berkeleylife.com   Sensate:  Go to getsensate.com ad use code NAT to save 10% off your purchase of the Sensate - an ultrasound resonance device that can improve Sleep, HRV and stress response.   Profound Health: Profound-Health is my first choice for oral and sublingual Bioregulator Peptides - the Nature’s Marvel Brand are oral Khavinson Bioregulators repackaged for the English speaking market. Use Discount code Longevity15 to save 15% off your first order!     Find more from Nathalie:   YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance Instagram: https://www.instagram.com/nathalieniddam/ Website: NatNiddam.com Join Nat’s Membership Community: https://www.natniddam.com/bsp-community Learn more about the 2023 Women’s Longevity & Resilience Retreat: https://www.natniddam.com/longevity-resilience     Find more from Joy Kong, MD:   Website: https://www.joykongmd.com/ and https://www.charaomni.com/ YouTube: https://www.youtube.com/channel/UCZj1GQBWFM5sRAL0iQfcMAQ Instagram: https://www.instagram.com/dr_joy_kong

If you’ve been wondering what exactly bioregulators are and what differentiates them from the peptides you’re already familiar with, then this episode is for you.    Today we’re diving into the world of bioregulator peptides, and covering everything from how they work to where they come from. We’ll also discuss why there has been an increasing number of physicians that are starting to implement bioregulator peptides into their protocol, and how bioregulators are often used in conjunction with conventional therapy. We’ll also talk a bit about the history behind bioregulators, and the connection between bioregulator peptides and the 12 hallmarks of aging.   Thank you to our sponsors for making this episode possible: Sensate: Use promo code NAT at getsensate.com to save 10% on your order.   Find more from Nathalie: Find More From Nathalie YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance Instagram: https://www.instagram.com/nathalieniddam/ Website: NatNiddam.com Join Nat’s Membership Community: https://www.natniddam.com/bsp-community Work with Nat: Book Your 20 MInute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08 What we discuss: [00:07:08] A bioregulator peptide is an epigenetic switch [00:09:03] Who discovered bioregulators?  [00:11:55] Other than our own bodies, where else can we get bioregulators from?  [00:13:31] Taking extracts from tissues, glands, and organs to isolate bioregulator peptides  [00:17:31] The three different forms of bioregulator peptides [00:21:54] How safe are bioregulator peptides? [00:22:45] What are some of the organ systems that bioregulators address?  [00:25:34] Why bioregulators are often used in conjunction with conventional therapy [00:26:35] Why bioregulators don't need to be used indefinitely  Key Takeaways: Bioregulator peptides are molecules that can act as epigenetic switches, meaning they can modify gene expression without altering the genetic code itself. By selectively turning on or off certain genes, bioregulator peptides can help regulate a variety of biological processes, from inflammation and immune response to tissue repair and regeneration.  There are currently 21 bioregulator peptides that address many different organ systems and can be used to improve your overall health. These peptides are derived from various sources, including plant and animal tissues, and work by signaling cells to perform specific functions. In many cases, bioregulators are used to enhance the effects of other forms of treatment. For example, they may be used alongside medication or physical therapy to help improve overall health and well-being. By using bioregulators in combination with conventional therapy, patients may be able to experience greater symptom relief and faster healing times.