The Jesse Chappus Show

Dr. Lily Johnston is a board-certified vascular surgeon, public health expert, and author of Disconnected. She discusses how medicine became a business, why prevention and metabolic health are overlooked, and the hidden costs of physician burnout and hierarchy. They also explore personalized nutrition, medical uncertainty, rebuilding a meaningful life, and honoring patients’ goals when facing death.

Dr. Jack Wolfson is a cardiologist, author of The Paleo Cardiologist, and founder of Natural Heart Doctor. He explores the environmental and lifestyle factors behind heart disease, from toxins and seafood to insulin resistance, sunlight, sleep, fasting, movement, and mental health. He also shares his “eat well, live well, think well” framework and why he chose Costa Rica.

Mimi Morgan is a certified personal trainer and metabolic health practitioner who lives with Parkinsonism and chronic illness. She recounts a devastating decline, frightening symptoms, isolation, and a stroke and MRSA infection. Mimi discusses her shift to ketogenic and carnivore nutrition, strength training, faith, medication changes, and the ten-step ritual that helped rebuild her life. She now describes herself as in full remission and is training for the Camino de Santiago.

Dr. David Harper, a kinesiology professor and ketogenic nutrition researcher, explores keto beyond fat loss. They discuss GLP-1 drugs, visceral fat, muscle preservation, keto adaptation, salt and blood pressure, fruit and fiber, personalized food tolerance, protein, ketone testing, supplements, women’s health, and the emerging links between ketogenic metabolism and cancer biology.

Dr. Sarah Myhill is a British physician and author specializing in chronic fatigue and ME. She explores how thyroid function, mitochondria, gut fermentation, toxins, and nutrition shape energy. They discuss iodine, heavy-metal detoxification, paleo-ketogenic eating, food allergies, supplements, glucose monitoring, and isometric exercise for rebuilding energy.

Dr. Robert Cywes, a dual board-certified surgeon and metabolic health specialist, explores carbohydrate addiction, emotional eating, and insulin resistance. He discusses how excess sugar affects the liver, why boundaries and planned meals matter, and healthier ways to regulate emotions. The conversation covers animal-based nutrition, fasting, GLP-1 medication, movement, and the long road toward metabolic recovery.

Dr. Dominic D’Agostino, a University of South Florida researcher specializing in ketosis and metabolic therapies, explores the science and practice of sardine fasting. They discuss ketosis, appetite control, autophagy markers, cognitive performance, electrolytes, exogenous ketones, MCT oil, fish choices, and potential nutritional gaps. He also shares practical guidance for planning and tracking a three-day fast.

Dr. Matthew Phillips is a neurologist and researcher exploring metabolic and mitochondrial therapies for brain disease. He discusses the links between metabolic dysfunction, Alzheimer’s, Parkinson’s, ALS, and glioblastoma. Topics include fasting, ketosis, sleep, deep rest, mitochondrial health, cancer metabolism, and combining lifestyle strategies with conventional treatment.

Robb Wolf, former research biochemist, bestselling author, and LMNT co-founder, explores ancestral health beyond diet dogma. He discusses his recovery from severe illness, metabolic dysfunction, GLP medications, fasting, sunlight, sleep, electrolytes, and practical low-carb nutrition. He also shares training strategies for staying strong after 50 and explains why community may be a key pillar of healthy aging.

Dr. Anthony Jay, biochemist, author, and health consultant, explores what may drive arterial plaque beyond LDL alone. They discuss insulin resistance, fat-burning metabolism, seed oils, oxidation, microplastics, plant sterols, and the role of vitamin K2. The conversation also covers CAC scans, cardiometabolic testing, fasting, exercise, and emerging approaches to plaque reversal.