Discover the importance of exercise for fighting respiratory infections like COVID-19. Learn about the benefits of exercise in reducing infection severity, hospitalization, and risk of death. Explore how exercise reduces inflammation, optimizes energy production, and prevents T cell exhaustion. Find out how exercise promotes the release of myokines and mobilizes immune cells. Understand the role of exercise in repairing damaged cells and enhancing T-cell function in the immune response to COVID-19.

This podcast explores the benefits of creatine for muscle growth and exercise performance in hot weather. It discusses how creatine draws water into cells, acts as an ATP buffer, and improves hydration and plasma volume. The podcast also debunks myths about creatine causing muscle cramps, dehydration, and hair loss. It highlights the positive effects of creatine on power, output, muscle growth, and anabolic environment. The hosts address misconceptions surrounding creatine supplementation and emphasize its benefits for athletes.

Learn science-based exercise tips for building muscle and strength over 40 with limited time. Strategies include supersetting exercises, targeted warm-ups, and compound movements. Discover the effectiveness of training for speed and power, as well as the benefits of creatine and electrolytes

Dr. Seager discusses science and best-practices with cold immersions for supporting hormonal health. Sponsored: Support your Workout Sessions and Healthy Hydration with this Creatine Electrolyte Combo by MYOXCIENCE: bit.ly/electrolyte-stix Save 12% with code podcast at checkout Save $350 off an amazing Cold Water Immersion tank with code HIH350: morozkoforge.com Show Notes:   2:25 Surprise is a basic human emotion that opens all your senses. Surprise updates your belief systems. 03:20 Complete freedom from stress is death. Stress is part of what makes us alive. There is a systemic beneficial response. 03:40 Thermal contrast is used to measure physiologic responses to stress. Adapting to this kind of stress is a measure of your resilience. 04:40 It is your beliefs about stress being harmful that cause harm to your health. 05:00 Our ancestors lived in discomfort and sought comfort. We should be seeking discomfort. Intentional discomfort with recovery makes us more resilient. 07:10 Water cold as 60 degrees will help your metabolism. Psychological resilience begins at water about 39 degrees. 09:50 HRV improves with cold exposure. Your heart rate should expand or contract to adjust to the demands of your body. HRV is a physiologic measure of your psychological resilience. It makes your heart more resilient. 11:30 Ice cold water exposure activates thermogenesis, the autonomic nervous system, and production of neurotransmitters and hormones that your body needs when your fight/flight system is on high alert. 13:10 When you come out of the ice water, you feel like superman. 14:30 Autonomic conflict theory: You will gasp. Gasp reflex activates fight/flight, increases your heart rate. If you cannot calm your breath, you may hyperventilate. A countervailing reflex is the dive reflex where you automatically shut down your breath and metabolism goes into conservation mode. It conserves oxygen and builds up carbon dioxide and slows your metabolism. 61:10 Your heart rate goes up In an ice water bath, and your liver releases glycogen into your bloodstream to fuel your muscles. 16:30 Tipton’s hypothesis is that if you are subject to both the gasp and the dive at the same time, it will create an autonomic conflict that may cause your heart to skip a beat. It is potentially an issue with people with arrythmia. However, there are no documented cases of heart arrythmia and cold emersion causing issues. 17:25 Contraindications of cold exposure: drowning, hyperventilation, and breath hold. Hyperventilation purges the carbon dioxide from your system and can shut down the receptors that give you the urge to breathe. 18:40 Go feet first. Bathe sober. Breathe continuously. 20:25 Primary Raynaud is a complex extreme over reaction to cold. It is partly physiological and part psychological. In general, cold induces vasal restriction. To protect your core, your body changes the circulation of your blood, shutting off circulation to your fingers, toes, and limbs. It reduces heat extraction.  Secondary Raynaud is a vascular disorder caused by some other disease. 22:10 Anxiety makes a Raynaud response worse, which makes the anxiety worse. 22:25 Exposure therapy has been a successful method for overcoming primary Raynaud. 28:40 You can micro dose cold exposure. The first 15 seconds bring on an autonomic response, fight/flight. Consistency is important. 32:14 Tom brought down his PSA to 0.8 with keto and more consistent ice baths. 32:40 Testosterone goes up when a cold bath is done before exercise. Do not ice bath for recovery if you are trying to build muscle mass. 36:00 Precool (cold exposure) before exercise for peak muscle power, endurance. Precooling protects mitochondria. Testosterone response goes way up. 36:55 Cold stimulation in women raises saliva testosterone. Testosterone is the dominant sex hormone in women, but not to the same levels as men. Testosterone is important for women at all ages. Menopausal women who experience a testosterone deficiency have no FDA approved treatments. 42:40 Brown fat is an essential organ. 30% of babies’ weight is brown fat. 43:40 Without regular cold exposure, you will lose all your brown fat. By age 40, 95% of Americans have 0 detectable brown fat. 43:55 Metabolic disorders are associated with a lack of brown fat. It is a secretory organ. It makes hormones. It makes more thyroid stimulating hormone than any other thing in your body.  Thyroid and brown fat work together. If your brown fat has dissipated, there is nothing to modulate thyroid activity.  Hyper or hypothyroidism is common in people with no brown fat. 44:40 Cold exposure is a potential remedy for thyroid disorder that does not require a lifetime of RX meds. 45:00 Beiging white fat, recruits more brown fat into your body. Brown fat produces neuroprotective hormones for your brain, thyroid stimulating hormone, and it will modulate your metabolism to bring it back to order. 46:55 Everyone’s body is evolutionarily designed to expect cold exposure, exercise, and certain nutrition. 48:25 People who live in thermal neutral environments generally have a higher rate of adiposity. 49:00 Cold exposure burns fat and calories when you are in it, but your body compensates for the caloric deficit after.  50:10 Cold exposure remodels your fat. It changes visceral fat into subcutaneous fat. Subcutaneous fat can be benign. Visceral fat (pot belly fat) can kill you. 50:40 Electrical impedance meter is not calibrated for brown fat. Don’t worry about absolute numbers. 54:40 Eleven minutes a week is enough time to keep brown fat working. 59:44 Ice bath can provide the emotional arousal needed to consolidate short-term memory into vivid long-term memory. 01:00:40 Shivering can be for thermogenesis, and it can be for nervous system release. Your nervous system can release trauma via trembling. PTSD is unresolved stress. Trauma is when stress has no release or resolution. 01:06:55When buying an ice bath: What is its temperature? Is it grounded? The tub must be electrically connected to the earth. What kind of water treatment does it have? Ozone is the most powerful water disinfectant for cold water. 01:10:40 Tom adds Epsom salt, potassium sulfate, zinc sulfate, and he does not shower after. Magnesium is stored in your bones, not your blood. Keep chloride out of your ice bath.

Let's discuss several new studies comparing how amino acids from plants VS animals differ in their ability to stimulate muscle protein synthesis. Support your Workout Sessions and Healthy Hydration with this Creatine Electrolyte Combo by MYOXCIENCE: http://bit.ly/electrolyte-stix Save 12% with code podcast at checkout Optimize your sleep with the best temperature controlled mattress available: www.eightsleep.com/hih Links to Studies: https://bit.ly/3OHm024 Show Notes:  00:50 Strength, body composition, muscle size, and muscle circumference did not differ between chronic vegan and omnivorous diets. 01:30 Resistance training and consuming protein stimulates muscle protein synthesis. 02:00 Plant and animal-based proteins differ in essential amino acid content and digestibility. 02:35 Higher levels of leucine and essential amino acids are in animal foods. Plants are a poor source. 05:20 It is more difficult to get essential amino acids in a small number of calories in plants. You need to eat a lot more calories of plants. 08:40 Plant-based proteins are more directed toward oxidation than muscle protein synthesis. 09:20 Plant-based proteins result in lower muscle protein synthesis response compared to an equivalent amount of animal protein. 11:45 You can get enough essential amino acids on a vegan diet, but at the expense of added calories and agricultural chemicals. 12:00 Soy protein tanked Mike’s digestion and testosterone levels when he was young. 13:25 There were no significant differences in strength, muscle cross-sectional area and leg mass between vegan and omnivore diets with matched amounts of protein. 15:30 Vegans will likely need to supplement with protein to support muscle protein synthesis. 16:30 Catabolism of bone, joints, and collagen is higher with a vegan diet.

Serum creatinine is an indicator of lean body mass and muscle quality, new studies find. Sponsored: Support your Workout Sessions and Healthy Hydration with this Creatine Electrolyte Combo by MYOXCIENCE Save 12% with code podcast at checkout Links to Studies, Images and Video: https://bit.ly/44D6Kce Time Stamps: 00:00 Creatinine is independently associated with lean body mass, muscle strength, and muscle quality. 00:25 Serum creatinine is a marker of impaired kidney function. 00:40 Creatinine is a normal waste product of muscle metabolism. 00:50 Levels can be impacted by declining kidney function, inflammation, and blood pressure reduction medications. 01:00 Concentrations are impacted by age, sex, and body size. 01:30 Average muscle protein per kilo of body weight was higher in omnivores. 02:10 Serum creatinine is significantly lower in vegetarians. 03:00 There are statistically significant differences in hand grip strength between omnivores and vegetarians. 05:10 Creatinine levels over 1.4 mg/dl may be a marker of chronic kidney disease and poor kidney function. 06:00 Abnormal urinary creatinine to albumin ratio is a marker of kidney dysfunction. 07:05 Low serum creatinine can indicate acute illness, severe liver disease, loss of muscle mass, malnutrition, muscular dysfunction, dehydration, or sarcopenia. 07:30 Vegetarian diet, low body mass, and reduced strength are linked to low serum creatinine. 08:30 There is a correlation between quality of protein, quality of muscle tissue, and serum creatinine. 09:05 Omnivores have significantly greater dietary protein intake, serum creatinine levels, and grip strength. 09:45 Increasing protein above the RDA has beneficial effects on strength level in vegetarians.

Let's discuss ways to keep belly fat off as you get age and why protein paired with exercise is so critical when you diet to lose weight. Support your Workout Sessions and Healthy Hydration with the Electrolyte + Creatine Combo by MYOXCIENCE: https://bit.ly/electrolyte-stix  *Save 12% with code podcast at checkout References and Video: https://bit.ly/3NZlmeN Show Notes:  00:00 Intro 2:49 There is a cycle with aging of reduction of muscle mass and increase of fat mass.  3:30 Hormonal changes of aging change body composition, leading to the acceleration of muscle loss. 5:00 Diets should be paired with resistance and aerobic training. 6:00 Changes in muscle precedes fat gains.  7:30 Focus on muscle and protein intake. 9:55 Adipocyte number is set during adolescence.  10:10 Health at any size is a fallacy. 10:51 Fat cells become hypertrophied and become necrotic and die. 11:30 Excessive amounts of energy cause fat cells to become inflamed. 12:05 Overfilled fat cells spill lipids, and greatly affect your liver. 12:45 Dead fat cells cause metabolic immune debris. 14:00 Immune cells infiltrate your fat, creating inflammation. 14:45 Exercise helps prevent fat cell inflammation. 15:30 Belly fat is not benign. 15:50 Obesity causes changes in muscle tissue. 17:30 Walking builds capillary and mitochondrial density in muscles. 19:00 Leg training provides greater anabolic responses. 20:00 Age-related loss of muscle strength is 3x faster than loss of muscle mass. 21:30 Compound movements move 2 or more joints at the same time. 22:40 Combination of diet and exercise may be the most effective intervention.

Dr. Elly Michelle discusses the importance of tracking ovulation and using your cycle to gauge exercise volume and intensity as well as prioritizing protein for body composition. Support your Workout Sessions and Healthy Hydration with this Creatine Electrolyte Combo by MYOXCIENCE: https://bit.ly/43suwGu Save 12% with code podcast at check out Link to Video: https://bit.ly/43suwGu ------Show Notes---------------------- 00:00 Intro 02:50 The phases of a menstrual cycle 03:50 Ovulation requires a rise in LH and a rise in estrogen.  04:50 The drop in progesterone causes the shedding of the uterine lining.  05:15 You are only fertile for a 6-day window.  06:00 Basal body temperature is an accurate method for tracking fertility. 10:00 An anovulatory cycle is when a woman does not ovulate.  11:10 Signs of ovulation  15:50 You have to ovulate to have a true period.  17:15 Unopposed estrogen is linked to gut issues.  19:30 Hormonal IUDs only have synthetic progestin.  22:45 Hormones influence your overall wellbeing, mood, and sense of vitality.  23:45 Going off hormonal birth control  24:45 Your brain controls your hormones and your ovaries. 27:10 Pharmaceutical substances are not hormones.  28:00 Progesterone keeps estrogen in balance. 28:15 Ovulation is about more than reproduction.  29:00 Testing hormones 38:10 Low progesterone can be caused by stress, poor nutrition, and over training.  42:40 Estrogen is anabolic and helps build and maintain muscle mass.  44:20 Post menopause 44:40 Muscle building and recovery in a cycling woman  48:50 Anti-mullerian hormone  52:00 To support hormones, prioritize consuming protein.  55:30 Adaptogens can be useful, but they are not the magic fix.

Learn new strategies and tactics to slow the greying of hair and prevent hair loss as you age. Support your Workout Sessions and Healthy Hydration with the Electrolyte + Creatine Combo by MYOXCIENCE : https://bit.ly/electrolyte-stix  Use code podcast to save 15% Link to study: https://bit.ly/3PHGxVp References: Fernandez‐Flores, A., Saeb‐Lima, M. & Cassarino, D. S. Histopathology of aging of the hair follicle. J. Cutan. Pathol. 46, 508–519 (2019).   Papaccio, F., D′Arino, A., Caputo, S. & Bellei, B. Focus on the Contribution of Oxidative Stress in Skin Aging. Antioxidants 11, 1121 (2022).   Williams, R., Pawlus, A. D. & Thornton, M. J. Getting under the skin of hair aging: the impact of the hair follicle environment. Exp. Dermatol. 29, 588–597 (2020). Show Notes: 01:00 We may slow hair graying and hair loss by decreasing chronic inflammation. 02:00 By age 50, 50% of us will have 50% of our hair gray. 02:00 Over 1 year you lose .25% of your hair follicles. 03:00 post-menopausal women have a dramatic increase in follicle loss. 03:30 Oxidative stress can influence gray hair. 04:20 UV stress can affect the hair bulb. 04:40 There is a correlation between graying of hair, facial wrinkling, and crown top baldness and myocardial infarction in men. 08:00 With age, hairs are reduced in diameter and experience follicle miniaturization. 08:55 Chronic inflammation increases damage to DNA proteins and lipids within the hair follicle environment. 10:05 Collagen may be effective in preventing premature wrinkling of the skin and hair loss. 10:55 Bone mineral density correlates with hair loss and hair graying. 11:20 Slowing senescence and purging senescent cells happen with fasting and exercise. 12:25 Minimize exposure to pollution. Avoid excessive sun exposure. Avoid nutrition deficiencies. 13:30 Insulin resistance and PCOS can exacerbate hair loss. 14:00 Sometimes graying from environmental factors may be reversed. 14:30 52% of post-menopausal women experience hair loss. 14:40 Micronized progesterone can help women preserve the integrity of skin and hair follicle. 15:20 Lack of estrogen accelerates changes in hair follicle and skin aging. 17:45 Some shampoos can accelerate graying and hair loss. 18:35 Men with high levels of DHT, consider a ketoconazole shampoo.  

Let's discuss ways to prevent fat gain with age, focusing specifically on age-related hormonal and metabolic changes as well as fat cell physiology.  Sponsored: Support your Intermittent Fasting lifestyle with the Berberine Fasting Accelerator by MYOXCIENCE: Save 12% with code podcast at checkout Link to Video, Images and Research: https://bit.ly/44qTFSV Show Notes: 01:00 There are cellular changes within adipose tissue and skeletal muscle linked with aging. 01:47 As fat cells get older, they hold fat more tightly. 01:55 There is infiltration of immune cells within fat tissue. 02:35 Mitochondrial function decreases with aging. 03:00 Exercise purges senescent cells. 03:50 Serum DHEA decreases with age. 04:52 Hormonal changes in aging cause fat cells to misbehave leading to metabolic derangement. 08:45 Reduced testosterone and DHEA effect post meal fat storage in men. 09:40 Your upper body is more sensitive to storing lipids after a meal but can become overfilled. 10:30 Fat tissue inflammation can be linked to reduced physical activity. 11:12 As you get older and stop exercising, decrease protein, your fat cells become infiltrated and enlarged. 12:25 The more body fat you have, the more proinflammatory immune cells you have within your fat tissue. 13:20 Overfilled fat cells cause muscle cells to onboard more fat. 14:00 Physical training has a huge impact on preserving muscle protein synthesis. 15:50 Exercised muscles become more sensitive to nutrients. 16:30 Increase your protein intake as you get older. 17:30 Protein intake should be between 1.2 and 1.5. Grams per kilo of ideal bodyweight per day. 18:10 Fast twitch muscle fibers are preferentially lost with aging.