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To optimize strength and muscle gain, it is recommended to dedicate a minimum of four weekly sets per muscle group. This minimum volume helps prevent age-related muscle loss and supports hypertrophy and strength as you get older. Compound movements like hip hinges, squats, bench presses, and pull-ups are effective. It is advised to focus on rep ranges between six and 15 repetitions, targeting lower rep ranges for strength and slightly higher ranges for hypertrophy. Advanced training techniques like drop sets and super sets can cut training time in half while inducing hypertrophy.