Studies show testosterone fluctuates seasonally, peaking in the summer months and declining in the winter.  Support hormonal health MYOXCIENCE Nutrition Alpha Male Stack and more: https://bit.ly/hormone-support Use code Podcast to save Link to Video, Notes: https://bit.ly/3NKCXs1 Key Takeaways:   02:35 Testosterone levels peak during August and September and decline in winter. 03:30 More sunlight and higher temperature correspond with higher testosterone. 05:15 Changes in melatonin byproducts impact testosterone. 06:05 Physical activity is a potent stimulus of testosterone production. 08:44 Chronic UV exposure, in animal models, increased levels of sex hormones and more sexual responsiveness in humans. 10:10 Tentacle tanning may work, but it needs study. 12:45 Lower disease risk and mortality in men is linked with higher testosterone. 13:00 Low fat diets decrease T in men. 14:40 Zinc, boron, vitamin D, and magnesium impact testosterone.

New data suggests the age of your face as well as your perception of aging predicts your inner, biologic age. Support your Intermittent Fasting lifestyle with the Berberine Fasting Accelerator by MYOXCIENCE: Save 12% with code podcast at checkout Link to Show Notes & Video: https://bit.ly/the-dunedin-study References:   Elliott, M. L. et al. Disparities in the pace of biological aging among midlife adults of the same chronological age have implications for future frailty risk and policy. Nat Aging 1, 295–308 (2021).   Key Takeaways:   00:00 The age of your face reflects your inner biologic age. 01:10 Negative thoughts of aging are linked with accelerated aging. 03:05 People who age faster, had significantly decreased cognitive function. 04:00 Will your future self approve of your habits of today? 04:43 Accelerated aging of your face reflects accelerated aging in your brain. 06:50 Disease states associated with acerated aging: High blood pressure, chronic kidney disease, cardiovascular disease, obesity, and loss of strength. 08:20 You can slow the aging of your face and body by changing your habits. 08:40 Reduce your feeding window. 09:30 Biologic aging impacts organs.

Age related muscle loss is accelerated by underuse, new studies find.  Support your Workout Sessions and Healthy Hydration with the Electrolyte + Creatine Combo by MYOXCIENCE : https://bit.ly/electrolyte-stix  Use code podcast to save 15% Link to study: https://bit.ly/slow-muscle-loss Show Notes:  0:00 Intro 0:30 As you age, you move less. 2:40 Aging is associated with changes in muscle metabolism and a decline in functional capacity. 3:45 There is an increase in insulin resistance as you age.  6:00 Aging is associated with declines in skeletal muscle mass, sarcopenia and dynapenia. 6:50 Lean muscle loss occurs at .7 to .8%/year during your 70s.  7:30 Rate of muscle loss is greater in legs and lower extremities as you age. 8:10 Hand grip strength reflects your habits. 9:45 Increase your physical activity as you get older. 10:15 You preferentially lose fast twitch muscle fibers as you age. 13:10 Increase protein intake as you get older. 16:20 Do resistance training 3 to 4 days per week and walk 10,000 to 12,000 steps on most days. 16:47 You can overcome the age-associated declines in muscle protein synthesis and changes in muscle fiber type.

Removing all animal foods from your diet usually causes unfavorable health consequences, studies suggest. Let's discuss ways to avoid the micronutrient deficiencies that my be present on a plant-based diet. Related: Support your Workout Sessions and Healthy Hydration with the Electrolyte + Creatine Combo by MYOXCIENCE: Use code podcast to save 15% Link to video, images and articles: https://bit.ly/43PdfaX Show Notes:   01:28 Deficiencies from these diets cause hair loss (for women too), hormonal changes, skin issues, hypothyroidism, sarcopenia (muscle loss) osteoporosis, and bone fractures. 06:45 Professional medical organizations are promoting vegan and plant-based diets, despite evidence to the contrary. 09:33 There are 5x more former vegans or vegetarians than current ones. 10:00 Plant-based diets do not signify a reduction in all-cause mortality. 11:20 Linked with anxiety, neurologic dysfunction, cognitive impairment, Musculo-skeletal, and immunological issues. 12:00 Supplement with B12, zinc, omega 3 fats, selenium, iodine, and protein. 12:15 Depressive disorders are significantly more common in vegans and vegetarians. 13:30 Eating disorder occurrences are higher in vegans and vegetarians. 16:20 Humans are omnivores. 18:10 Vegans/vegetarians may be more health conscious, which overestimates the health benefits of the diet when compared to other diets. 19:20 Nose to tail eating. 22:25 Supplementing with collagen, organic bone meal, omega 3 fats, and glycosaminoglycan chondroitin may be helpful. 22:50 Processed, overcooked, or burned meat is harmful. 23:20 Fermented foods are more digestible. 25:30 The scientists promote a plant forward omnivorous diet.  

Zinc is an essential mineral involved in over 200 enzymatic reactions. Science shows it may help support hormonal health in men. Support your hormone health with the Alpha Male Stack by MYOXCIENCE Nutrition: https://myoxcience.com/collections/hormone-adrenal-support Save with code podcast at checkout Video and Show Notes: https://bit.ly/43gKHax Time Stamps:   00:30 Zinc supplementation can increase Testosterone levels. 01:55 Zinc is an essential nutrient that plays many roles. 02:10 Testosterone is an androgen that plays many roles. 02:35 Zinc deficiency leads to structural changes within testicles and impairs testosterone synthesis. 04:00 The conversion of testosterone to its active form requires 5 alpha reductase, which is dependent upon zinc. 04:30 Zinc deficiency may lead to decreased male hormone receptor activity. 05:30 Mike recommends zinc bisglycinate chelate bound to glycine. 07:30 Zinc is lost in sweat and ejaculate. 09:30 Consider your zinc-copper ratio. 09:58 Low testosterone increases risk of cardiovascular disease, depression, cerebral vascular disease, insulin resistance, and increased belly fat.  

Charles Poliquin shares key insights from his four decades of experience training elite athletes and Olympians.  Support your Workout Sessions and Healthy Hydration with the Electrolyte + Creatine Combo by MYOXCIENCE: https://bit.ly/electrolyte-stix  *Save with code podcast at checkout Video Interview:  https://youtu.be/1ojJF3Oqanw Get the Blood Work Cheat Sheet: https://courses.highintensityhealth.com/blood-work-cheat-sheet Arm Size and Strength: The Ultimate Guide: http://amzn.to/2kOzo78 Show Notes 0:00 Intro 4:19 To win the war on fat, you need to win the insulin war. 5:43 Athletes’ Alzheimer’s propensity 6:19 Profound benefits of strength training 7:39 You don’t need carbs.  8:41 Risk/benefit of peptides like SARMs (Selective Androgen Receptor Modulator) 10:12 The beneficial hormonal influence of doing squats 11:30 DHEA Sulfate, the mother of all androgens 13:50 DHEA for women 15:37 The best anabolic agent is sleep. 17:03 Screen time affects androgens, sleep, weight gain, fitness, and information retention. 21:50 Carbohydrates are not for everyone. 26:20 Managing stress hormones with carbohydrates  26:40 Meat, wild and domestic, sources of protein 29:06 Meal timing and frequency 31:13 Athletic performance with intermittent fasting and protein/fat consumption  35:39 Regular blood work is a lie detector. 39:18 Leucine and branch chain amino acids for hypertrophy 42:08 Fish oil for weight loss 44:26 GLA (Gamma-linolenic acid), the healthy Omega 6 45:05 Periodization for burning fat and building muscle 51:23 Mindset and quality over quantity 59:55 Charles’ morning routine 01:04:04 Charles’ favorite nutrients/foods are brain-ready carnitine, curcumin and water buffalo. 01:05:54 Charles’ elevator pitch would be to ban soda and look to the Finns for education reform.

Remnant lipoproteins are being recognized as a better proxy for metabolic health.   Support your Intermittent Fasting lifestyle with the Berberine Fasting Accelerator  by MYOXCIENCE: bit.ly/berberine-fasting-accelerator  Use code podcast to save 12% Get the Blood Work Cheat Sheet: https://courses.highintensityhealth.com/blood-work-cheat-sheet 00:00 Remnant cholesterol is an atherogenic lipid. 01:10 Remnant cholesterol is linked with metabolic dysfunction. 02:10 Remnant cholesterol is a good assessment for non-alcoholic fatty liver disease, diabetes, hypertension, chronic kidney disease, and atherosclerosis diseases.  02:27 Total cholesterol – HDL – LDL = Remnant Cholesterol. 07:45 Remnant cholesterol levels, with high accuracy, identify metabolic syndrome. 08:50 Remnant cholesterol is a measure of the triglyceride enriched atherogenic lipoprotein.  10:00 Industrialized seed oils increase the propensity of your atherogenic lipoproteins to become oxidized. 10:50 Women have a higher risk of metabolic syndrome related to remnant cholesterol. 11:50 Older women have significantly higher bodyfat percentage, worse lipid profiles, and worse lipid metabolism then men and younger women. 13:30 Skeletal muscle is important to metabolic health. 14:40 Menopausal bioidentical HRT reduces the risk of a number of diseases.

Record numbers of young women are experiencing early menopause, also known as Premature Ovarian Failure, in their 20s and 30s. Here's the science and details you should know. Support your sleep, mood and metabolic health with Myo Relax and Calm by MYOXCIENCE: bit.ly/myo-relax-sleep-blend Use code podcast at checkout to save Link to video and research: https://bit.ly/3NZeWOv Time Stamps: 00:00 Young women in their 20s and teen girls are going through menopause, premature ovarian insufficiency. 00:37 Nearly 11% of women in North America go through POI. 01:45 POI is a symptom of endocrine disrupting chemical exposure, poor metabolic health, and malnutrition. 03:45 Long-term health issues are caused by low estrogen, progesterone and testosterone. 04:50 Early symptoms 05:30 Indicators: elevated FSH, between 25 IU and 40 IU, and low AMH, below 3.5 picomoles/liter. 06:24 Exposure to certain environmental chemicals compromise reproductive health in women. 10:35 POI is ovarian failure, not early menopause.

Heart disease and cancer have long held the top two causes of death, 2022, 2021 and 2020 were no different, new data suggests. According to the CDC’s recently released 2022 figures, these two health conditions claimed a combined 7 times more lives than COVID-19 in 2022.  Support your Workout Sessions and Healthy Hydration with the Electrolyte + Creatine Combo by MYOXCIENCE: bit.ly/electrolyte-stix Use code podcast to save 12% Link to video review and notes: https://bit.ly/top-cause-of-death-2022 References: Ahmad, F. B., Cisewski, J. A. & Anderson, R. N. Provisional Mortality Data — United States, 2021. Morbidity Mortal Wkly Rep 71, 597–600 (2022).

Hormonal birth control is linked with altered mood states, including anxiety and depression as well as exaggerated responses to stress.  Sponsored Message: Support your sleep, mood and metabolic health with MyoRelax and Calm by MYOXCIENCE: https://bit.ly/myo-relax-sleep-blend Use code podcast at checkout to save Link to imagers and articles: https://bit.ly/44HIPZM Time Stamps:  00:00 Altered mood states are linked with hormonal birth control. 00:50 IUD’s, other than copper, contain progestins and some have estrogens. 02:00 Elevated depression and stress scores, elevated CRP, and plasma cortisol, are found from hormonal birth control. 04:00 Exaggerated basal neuroendocrine and inflammatory profiles are found with hormonal contraceptive users. 04:20 Hormone users had double the amount of cortisol compared to non-users. 04:40 Synthetic progestins and estrogens are not the same as biologically identical progesterone and estradiol. 07:20 Depression increases your risk from dying from all causes, particularly from cardiovascular disease. 07:45 Neurotransmitter GABA is sensitive to changes in progesterone. 10:50 Neuroactive steroid hormones and the HPAG axis are altered with synthetic hormonal contraceptives. 13:10 History of psychiatric illness increases likelihood of poor mental health while using hormonal contraception. 14:30 Explore birth control alternatives.   Studies Mentioned:   1.Skovlund, C. W., Mørch, L. S., Kessing, L. V. & Lidegaard, Ø. Association of Hormonal Contraception With Depression. Jama Psychiat73, 1154 (2016).   2.Lewis, C. A. et al. Effects of Hormonal Contraceptives on Mood: A Focus on Emotion Recognition and Reactivity, Reward Processing, and Stress Response. Curr Psychiat Rep 21, 115 (2019).   3.Elsayed, M. et al. The potential association between psychiatric symptoms and the use of levonorgestrel intrauterine devices (LNG-IUDs): A systematic review. World J Biological Psychiatry 1–19 (2022) doi:10.1080/15622975.2022.2145354.   4.Raeder, F. et al. Do oral contraceptives modulate the effects of stress induction on one-session exposure efficacy and generalization in women? Psychopharmacology 240, 1075–1089 (2023).   5.Lacasse, J. M., Ismail, N. & Tronson, N. C. Editorial overview: Hormonal contraceptives and the brain: A call for translational research. Front Neuroendocrin 69, 101063 (2023).   6.Martell, S., Marini, C., Kondas, C. A. & Deutch, A. B. Psychological side effects of hormonal contraception: a disconnect between patients and providers. Contracept Reproductive Medicine 8, 9 (2023).   7.Zettermark, S. et al. Population heterogeneity in associations between hormonal contraception and antidepressant use in Sweden: a prospective cohort study applying intersectional multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA). Bmj Open 11, e049553 (2021).