

The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.This isn’t just self-improvement - it’s human enhancement backed by data.Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
Episodes
Mentioned books

Jan 13, 2021 • 57min
What’s Up with Water Fasting? – Dr. Alan Goldhamer with Dave Asprey : 780
Dr. Alan Goldhamer, a leading expert in medically supervised water-only fasting and founder of TrueNorth Health Center, shares fascinating insights on the health benefits of water fasting. He reveals how the body self-cleanses during fasting and the positive effects on gut health. The conversation also highlights the importance of adhering to fasting protocols for safety and discusses the impact of whole plant foods on longevity. Finally, Goldhamer tackles common myths about sodium intake and the individualized approaches needed for effective fasting.

Jan 8, 2021 • 38min
Bonus: Intermittent Fasting Boosts Brain Power: Mark Mattson, Ph.D., with Dave Asprey
Mark Mattson, Ph.D., a renowned neuroscientist from Johns Hopkins Medicine, shares groundbreaking insights on intermittent fasting's effects on brain and body health. He discusses how fasting enhances cognitive function and can combat obesity and diabetes when combined with exercise. Mark also highlights the role of natural compounds in boosting performance and the benefits of specific beverages and medicinal mushrooms for brain health. This enlightening conversation emphasizes the importance of balanced nutrition and mindful eating in maximizing the benefits of fasting.

Jan 7, 2021 • 56min
Women, Fasting, Keto & Cancer – Amy Robach with Dave Asprey : 779
Amy Robach, a prominent journalist and ABC News co-anchor, shares her life-altering journey after a shocking breast cancer diagnosis from a live mammogram. She discusses the transformative power of keto and intermittent fasting in her recovery and emphasizes the importance of proactive health decisions. The conversation includes insights on combating procrastination in health checks, navigating dietary choices for cancer survivors, and empowering others with knowledge about healthier eating. Robach’s story inspires a deeper look at diet, sugar’s risks, and the emotional resilience required in the face of adversity.

Jan 5, 2021 • 47min
Bad Science and Diet Lies Keep Feeding Obesity: Gary Taubes with Dave Asprey : 778
In this insightful discussion, Gary Taubes, an award-winning science journalist known for challenging conventional dietary wisdom, delves into the myths surrounding obesity and the failings of mainstream dietary advice. He critiques the 'calories in, calories out' model, exploring how hormonal factors and outdated beliefs have fueled current obesity rates. Taubes emphasizes the importance of understanding diets like keto and intermittent fasting, advocating for a reevaluation of what we consider healthy eating to combat the epidemic effectively.

Dec 30, 2020 • 60min
When Mother Nature Says, ‘I’m Out,’ Geoengineering Hacks Will Fix Our Planet: Thomas Kostigen with Dave Asprey : 777
Thomas Kostigen, a bestselling author and National Geographic journalist, dives into revolutionary geoengineering solutions for climate change. He discusses innovative ideas like space umbrellas and marine cloud brightening, emphasizing the urgency of immediate solutions amidst extreme weather events. Kostigen critiques public perceptions and advocates for scientifically grounded strategies to combat environmental degradation. He reflects on the ethical responsibility of parenting in a climate-crisis world and calls for collective action to reimagine a sustainable future.

Dec 29, 2020 • 51min
Censorship Costs Lives: Brian Rose Keeps it Real in London with Dave Asprey : 776
Brian Rose, founder and CEO of London Real, passionately discusses the implications of censorship in media. He shares firsthand experiences of having his content removed without notice and the launch of his Digital Freedom Platform to champion diverse voices. Delving into his mayoral campaign, he critiques UK pandemic responses, advocates for focused protection strategies, and emphasizes the importance of free speech in political discourse. Brian's insights reveal the need for authenticity and transparency in leadership, particularly in today's digital landscape.

Dec 22, 2020 • 1h 1min
You’re Actually Not a Badass and Here’s Why – Scott Barry Kaufman, Ph.D., with Dave Asprey : 775
Scott Barry Kaufman, a humanistic psychologist and author, dives deep into the quest for self-actualization. He reveals insights from his research on Abraham Maslow's unfinished theory of transcendence, advocating for a shift in the narratives we tell ourselves. The discussion highlights the importance of vulnerability, self-awareness, and how embracing our psychological complexity fosters personal growth. With a humorous nod to nerd culture, Kaufman emphasizes the joy of creativity and the transformative power of understanding our human potential.

Dec 20, 2020 • 41min
BONUS: Take This Step to Create the Best Year of Your Life – Jack Canfield with Dave Asprey : 774
Jack Canfield, America's No. 1 Success Coach and co-creator of Chicken Soup for the Soul, shares insights on finishing the year strong and embracing personal growth. He introduces his 16-week Coaching Club, emphasizing accountability and community support. Canfield discusses the importance of gratitude amid adversity and how it can foster resilience. He highlights the shift to online coaching as a way to reach diverse audiences, and encourages listeners to visualize their goals, likening them to a script that requires commitment for transformation.

Dec 18, 2020 • 14min
Mini-Episode: Cool Facts Friday #6
Discover how loneliness can trigger hunger signals in the brain. Find out about a groundbreaking drug, ISRIB, that may reverse age-related cognitive decline in no time. Explore the intriguing link between gut health and mental well-being, with gastro issues possibly influencing behavior. Learn about the two phases of degenerative diseases and the effects of sleep deprivation on oxidative stress. Lastly, dive into the challenges of farming on Mars, where human adaptation is key to success.

7 snips
Dec 18, 2020 • 59min
Trigger Autophagy Without Fasting – Dr. Elizabeth Yurth Talks Spermidine with Dave Asprey : 773
Dr. Elizabeth Yurth, the Medical Director of Boulder Longevity Institute and a pioneer in spermidine research, shares insights on how this natural compound can enhance cellular health and slow aging. She explains spermidine's role in promoting autophagy, which helps recycle damaged cells, and its benefits for memory, sleep, and energy levels. The discussion also covers the safety of spermidine supplementation, its impacts on immune function, and its potential to improve hair growth and overall wellness, making it an exciting breakthrough in longevity science.


