
 The Human Upgrade: Biohacking for Longevity & Performance
 The Human Upgrade: Biohacking for Longevity & Performance Bonus: Intermittent Fasting Boosts Brain Power: Mark Mattson, Ph.D., with Dave Asprey
 Jan 8, 2021 
 Mark Mattson, Ph.D., a renowned neuroscientist from Johns Hopkins Medicine, shares groundbreaking insights on intermittent fasting's effects on brain and body health. He discusses how fasting enhances cognitive function and can combat obesity and diabetes when combined with exercise. Mark also highlights the role of natural compounds in boosting performance and the benefits of specific beverages and medicinal mushrooms for brain health. This enlightening conversation emphasizes the importance of balanced nutrition and mindful eating in maximizing the benefits of fasting. 
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Exercise and Fasting Routine
- Skip breakfast and work out midday or early afternoon.
- This leverages the metabolic switch from glucose to ketones.
mTOR, Autophagy, and Cellular Renewal
- Both exercise and fasting activate mTOR and autophagy, which clear out cellular garbage.
- Combining both amplifies these effects for better cellular cleaning.
Plant Toxins and Stress Response
- Beneficial plant chemicals act as mild toxins, activating stress response pathways.
- These pathways, like Nrf2, boost antioxidant defenses, unlike supplemental vitamins.







