Mark Mattson, Ph.D., a renowned neuroscientist from Johns Hopkins Medicine, shares groundbreaking insights on intermittent fasting's effects on brain and body health. He discusses how fasting enhances cognitive function and can combat obesity and diabetes when combined with exercise. Mark also highlights the role of natural compounds in boosting performance and the benefits of specific beverages and medicinal mushrooms for brain health. This enlightening conversation emphasizes the importance of balanced nutrition and mindful eating in maximizing the benefits of fasting.
38:05
forum Ask episode
web_stories AI Snips
view_agenda Chapters
menu_book Books
auto_awesome Transcript
info_circle Episode notes
volunteer_activism ADVICE
Exercise and Fasting Routine
Skip breakfast and work out midday or early afternoon.
This leverages the metabolic switch from glucose to ketones.
insights INSIGHT
mTOR, Autophagy, and Cellular Renewal
Both exercise and fasting activate mTOR and autophagy, which clear out cellular garbage.
Combining both amplifies these effects for better cellular cleaning.
The Bulletproof Diet is a comprehensive guide to achieving better mental clarity, sustained energy, and weight loss through a high-fat, moderate-protein, and low-carbohydrate approach. The diet emphasizes eating organic, grass-fed, and non-GMO foods to minimize toxins and maximize nutrient intake. It also incorporates intermittent fasting and the consumption of healthy fats like avocados, coconut oil, and grass-fed butter. The diet aims to stabilize blood sugar levels, promote weight loss, and support cognitive function. Key components include the use of Bulletproof Coffee, avoiding mold toxins, and a balanced approach to exercise and sleep[1][3][5].
Mark, a neuroscientist at Johns Hopkins Medicine, is one of the world’s top experts on the health benefits of intermittent fasting on the brain and body.
Decades before intermittent fasting diets became popular, he began studying mouse models to understand how the brain adapts to challenges like fasting and exercise. He and his research teams have shown that fasting can improve cognitive function and metabolic health. See some of his current research in the New England Journal of Medicine on how fasting can help people live longer.
"Intermittent fasting and exercise can reverse diabetes, and obesity in humans if a person can switch their eating pattern, and get on an exercise program,” Mark says.
The Human Upgrade with Dave Asprey 
