The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.This isn’t just self-improvement - it’s human enhancement backed by data.Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
Episodes
Mentioned books
Dec 2, 2022 • 50min
Discovering Blue Zones In America – Dan Buettner : 1001
Dan Buettner, an explorer and National Geographic Fellow, delves into the secrets of Blue Zones—regions renowned for extraordinary longevity. He discusses how lifestyle choices, particularly nutrition and social connections, significantly impact lifespan. Buettner highlights his recent road trip across the U.S., uncovering hidden Blue Zone pockets, heritage recipes, and the plant-forward cuisine that thrives there. He emphasizes the balance between happiness and longevity, making a compelling case for mindful eating habits to enhance health and well-being.
10 snips
Nov 29, 2022 • 56min
The Bacteria That Lets You Drink Alcohol Again – Zack Abbott, Ph.D. : 1000
In this engaging discussion, Zack Abbott, CEO and co-founder of ZBiotics and expert in microbiology, reveals groundbreaking insights into genetically engineered probiotics. He introduces a new pre-alcohol drink that targets the hangover culprit, acetaldehyde, promoting healthier drinking habits. The duo dives into the potential of GMOs in food and health, and the role of gut microbiomes in alcohol metabolism. Abbott emphasizes responsible consumption while exploring the future of engineered probiotics in enhancing alcohol tolerance and overall wellness.
4 snips
Nov 25, 2022 • 8min
Mini-Episode: Cool Facts Friday #29
Discover the surprising teamwork of sperm that swim together to boost fertilization chances. Learn why late-night eating is particularly harmful to your health and how wearable tech can monitor your metabolic markers through sweat. Explore the science behind personalized nutrition and the connection between REM sleep and memory deletion. Uncover how eye movements can enhance brain function, blending modern technology with ancient practices for a unique approach to wellness.
5 snips
Nov 22, 2022 • 50min
How Urolithin A Helps Create Super T-Cells & Boosts Immunity – Dr. Anurag Singh : 999
Dr. Anurag Singh, an immunologist and Chief Medical Officer at Amazentis, dives into the fascinating role of urolithin A in boosting mitochondrial health and immune function. He explains how this compound helps rejuvenate our cells by cleaning up metabolic waste and enhancing the immune system's response to aging and cancer. With insights on the connection between inflammation and immunological strength, he reveals how urolithin A can empower T cells, offering a fresh perspective on maintaining health and vitality as we age.
Nov 18, 2022 • 1h 18min
Battling Pathogens and Building Immunity Begins In Your Gut – Dr. Robynne Chutkan : 998
Dr. Robynne Chutkan, a Yale- and Columbia-trained gastroenterologist and author of "The Anti-Viral Gut," delves into the profound connection between gut health and immunity. She emphasizes that resilience against viruses starts in the gut, discussing how a healthy microbiome can outpace pharmaceuticals. Dr. Chutkan shares insights on the impacts of C-sections and antibiotics on gut flora, the significance of dietary choices, and the importance of fecal microbiome transplants. She also highlights practical strategies to nurture gut health for better overall wellness.
5 snips
Nov 15, 2022 • 49min
How Sleep Tech Improves Your Performance – Matteo Franceschetti : 997
Matteo Franceschetti, the co-founder of sleep tech company Eight Sleep and a competitive athlete, shares insights on how sleep impacts human performance. He discusses AI-driven sleep technology designed to track biosignals and enhance rest. Matteo highlights the crucial link between sleep quality and athletic success, addressing innovations like temperature-adjusting mattresses. He also touches on nutrition, the benefits of napping, and the ethical considerations of AI in health, making a case for technological advancements in sleep monitoring.
16 snips
Nov 11, 2022 • 1h 9min
Sleep Breakthroughs, Stacks & Solutions – Matt Gallant : 996
Matt Gallant, co-founder of BiOptimizers and a biohacking expert, shares his extensive journey into optimizing sleep. He reveals practical tips on creating a sleep stack, discusses sleep disruptors, and highlights the importance of proper sleep positions. Gallant dives into innovative sleep devices, supplements, and personal anecdotes on overcoming sleep challenges. He emphasizes the significance of temperature control and mental wellness, making sleep optimization accessible for everyone to enhance overall performance and well-being.
Nov 9, 2022 • 50min
Skincare Hacks With Meteoric Results – Andy Hnilo : 995
Andy Hnilo, founder of Alitura Naturals and skin health advocate, dives into innovative skincare solutions. He highlights the importance of using natural ingredients like pearls and meteorites, stressing how toxic fillers harm skin. The conversation covers the rise of adult acne and the power of nutrition and fitness upgrades for skin health. Hnilo shares his personal battle with acne, offering tips on ingredient labels and the benefits of supplements and unique formulations. Get ready for insights on holistic skincare and sustainable packaging!
Nov 5, 2022 • 43min
Upgrade Spotlight: Calm the Chaos, Then Drink the Water – Analemma : 994
Mario Brinovic, CEO of Analemma Water, reveals the groundbreaking science behind transforming ordinary water into a supercharged, coherent state. He explains how this unique device organizes water molecules, potentially enhancing health and energy at a cellular level. Brinovic shares insights on the impact of structured water on taste, plant vitality, and even agricultural practices. The conversation dives deep into the importance of water quality for both humans and ecosystems, sparking curiosity about innovative hydration solutions for better well-being.
20 snips
Nov 3, 2022 • 55min
Sauna Big Wins: Body Detox & Depression Relief – Connie Zack : 993
Connie Zack, an innovator in infrared sauna manufacturing with over 22 years of experience, joins the conversation to discuss the transformative power of infrared light therapy. She highlights how saunas can boost energy, aid detoxification, and improve mental health, including relief from depression. The connection between infrared wavelengths and enhanced sleep quality is also explored. Connie emphasizes practical tips for incorporating sauna sessions into daily routines to maximize health benefits, combining light and heat for a holistic approach.
