Dr. Michael Gervais, expert in managing thoughts, staying present, and letting go of people pleasing, dives deep into topics such as managing unproductive thoughts, the connection between quality sleep and being your best, and how disordered thinking takes shape from microtraumas. They also discuss practical strategies for redirecting unhelpful thoughts, the importance of squaring up with discomfort and pain for true change, and how to develop your "It Factor" through psychological skills and practices.

Dr. Brené Brown, a renowned expert on vulnerability and courage, discusses the fear of other people's opinions and the power of healthy partnerships. They explore the importance of vulnerability and courage in leadership, personal growth, and relationships. The chapter also delves into the interplay between vulnerability and trust, emphasizing authenticity and setting boundaries. Trust and open communication are highlighted, and the hosts express their appreciation for the guest's insights.

Dr. Woody Hoburg, a NASA astronaut, gives a firsthand look into life aboard the International Space Station, discussing the importance of relationships and communication in space. He also talks about managing the unknown in high-pressure environments and the impact of day-night cycles on sleep and work patterns. The podcast ends with expressing gratitude and encouraging support for the show.

Woody Hoburg, a NASA Astronaut, shares his experience in preparing for a space mission. Topics discussed include the selection process, mental imagery for space travel, the responsibilities of a pilot, continuous improvement within the astronaut core, exploring potential and testing limits, and the impact of loss on the emotional aspects of training.

Neuroscientist Dr. David Eagleman discusses the importance of constantly challenging the brain, the significance of living in the present moment, and the role of novelty in brain performance. The speakers also explore using others as reference points for personal growth, overcoming temptations and pitfalls, and the dynamics of in-groups and out-groups. They touch on rationalization, effective learning conditions, and express appreciation for the listeners.

Tommy Caldwell, a legendary professional big wall rock climber, shares his experiences of scaling the infamous Dawn Wall and being taken hostage in Kyrgyzstan. He discusses the power of elective hardship and how it can lead to personal growth and resilience. Tommy's story is a testament to pushing boundaries and achieving the seemingly impossible.

Dr. Michael Gervais discusses the fear of people's opinions (FOPO) and explores topics such as being authentic in social settings, redefining success, bringing vibrance into life, and self-love. They also touch on coping with hearing loss, pursuing passion despite opposition, exploring bias, and navigating social situations.

Dr. Robert Sapolsky, an expert in the science behind our everyday decisions, challenges the concept of free will and argues that our actions are driven by factors beyond our control. He explores the influence of biology, environment, and intent on decision making. The podcast also discusses the impact of factors like fatigue, hunger, and hormones on our choices, and emphasizes compassion towards neurological conditions. It explores the concept of free will's effect on joy and happiness, determinism and personal agency, and the role of external influences on decision making.

Thomas Curran, a professor of psychology, discusses the overwhelming pressure of perfectionism. They explore its roots, impact on mental health, importance of embracing imperfections, and finding healthier paths to growth and fulfillment. They also touch on challenges of parenting, understanding metabolic health and nutrition, and the difference between high standards and perfectionism.

Paula Schneider, CEO of Susan G. Komen, shares her inspiring journey through breast cancer and corporate turnarounds. Topics include accepting help during illness, leading through uncharted territory, proactive cancer prevention, and making decisions with imperfect information. Paula reshapes our understanding of success and demonstrates the power of facing and conquering the hard things in life.