JAMA Editors' Summary

Delve into the MYPP trial findings on myo-inositol's impact for pregnant individuals with PCOS, revealing it doesn't significantly reduce pregnancy complications. Discover innovative MRI techniques for prostate cancer detection and the advantages of biparametric MRI. Explore pivotal findings enhancing patient care, such as early childhood blood pressure's link to cardiovascular risks. Celebrate the Lasker Awards, spotlighting groundbreaking contributions to medical science, including heartfelt stories of impact. Lastly, get insights on viral infections and obesity treatments from recent JAMA articles.

Recent research reveals the RSV vaccine's effectiveness in reducing hospitalizations among older adults. Vaccination's impact on cardiovascular health is also explored, alongside groundbreaking trials on atrial fibrillation and myocardial infarction. Discussions include gaps in cancer drug trials and the role of AI in medical imaging. Additionally, insights into methamphetamine use disorder are shared, along with promising findings on using LSD for anxiety, and awareness of paternal mental health during the perinatal period is raised.

Gregory Curfman, Executive Editor at JAMA, and Robert O. Bonow, JAMA Cardiology Editor, tackle pressing advancements in cardiac care. They discuss the benefits of remote ECG monitoring for atrial fibrillation detection and the safety of discontinuing anticoagulants post-ablation. The duo also dives into the comparative effectiveness of semaglutide and tirzepatide in heart failure treatment. Lastly, they underscore the significance of bivalent RSV vaccination for older adults, while highlighting the need for greater female representation in cardiovascular trials.

Editor’s Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief, and Preeti Malani, MD, MSJ, Deputy Editor of JAMA, the Journal of the American Medical Association, for articles published from August 23-29, 2025.

Editor’s Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief, and Preeti Malani, MD, MSJ, Deputy Editor of JAMA, the Journal of the American Medical Association, for articles published from August 16-22 2025.

Editor’s Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief, and Preeti Malani, MD, MSJ, Deputy Editor of JAMA, the Journal of the American Medical Association, for articles published from August 9-15, 2025.

Editor’s Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief, and Preeti Malani, MD, MSJ, Deputy Editor of JAMA, the Journal of the American Medical Association, for articles published from August 2-8, 2025.

Discover how structured lifestyle interventions can enhance cognitive function in older adults through exercise, diet, and social activities. Learn about the severe impacts of influenza on children, including critical neurological conditions. Delve into the complexities of drug pricing and the push for transparency in Alzheimer's treatment. Lastly, uncover intriguing links between patent foramen ovale and stroke, along with insights into managing cognitive impairment and obesity medications.

Editor’s Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief, and Preeti Malani, MD, MSJ, Deputy Editor of JAMA, the Journal of the American Medical Association, for articles published from July 19-25, 2025.

Editor’s Summary by Linda Brubaker, MD, and Preeti Malani, MD, MSJ, Deputy Editors of JAMA, the Journal of the American Medical Association, for articles published from July 12-18, 2025.