JAMA at AHA, Review of MASLD, Primary Biliary Cholangitis, and more

Dr. Stefan Tilg, an experienced hepatologist and author, dives into the intricacies of metabolic dysfunction-associated steatotic liver disease (MASLD). He reveals how modest weight loss can significantly impact liver health—5% for steatosis, 7–10% for inflammation, and up to 15% for fibrosis regression. The discussion also highlights the benefits of a Mediterranean diet and physical activity in improving liver conditions, even without weight loss. Additionally, there's a concise update on primary biliary cholangitis, shedding light on this rare autoimmune disease.