On today’s podcast, Paul debunks an article claiming that animal centered diets accelerate aging. He breaks down the epidemiology and observational evidence in this article, explains healthy user bias and unhealthy user bias, and shares studies that support his belief that in fact, vegan diets induce frailty, which in turn, accelerates aging. 00:10:31 Paul shares the article that claims that eating meat accelerates aging 00:15:23 Understanding healthy user bias, unhealthy user bias and epidemiology studies 00:20:45 The benefits of eating meat for longevity 00:24:10 Is meat inflammatory? 00:30:40 Vegans and fracture risk 00:34:04 Did our ancestors eat a lot of meat? Do they age well? 00:39:00 Are the Blue Zones BS? 00:42:25 Picking apart the studies that claim plant-based diets reduce affects of aging 00:46:23 Does restricting calories lead to longevity? 00:49:10 Sarcopenia as a predictor of all-cause mortality 00:50:40 Flaws in famous studies promoting plant-based eating 00:54:40 Should we worry about mTOR? 00:56:05 Should we worry about IGF-1 when eating dairy and carbohydrates? 01:01:45 PUFAs 01:09:55 Soy protein vs animal protein 01:11:10 Anecdotal evidence from the article 01:14:38 Recapping the episode Sponsors: Heart & Soil: www.heartandsoil.co Carnivore MD Merch: www.kaleisbullshit.shop Make a donation to the Animal Based Nutritional Research Foundation: abnrf.org Animal-based 30 Challenge: https://heartandsoil.co/animalbased30/ Bon Charge: boncharge.com, use code CARNIVOREMD for 15% off your order Our Sponsor LetsGetChecked: 20% off your order at www.TRYLGC.com/paulsaladino for 25% off Eight Sleep: www.eightsleep.com/carnivoremd to get $150 off your order Colima Salt: drpaulsalt.com, for a free bag of Colima Sea Salt p ;.;

This week, Paul covers several topics at a high level, alongside referencing previous detailed episodes. He is answering questions from his listeners about why animal-based eating is optimal, why meat is not harmful for humans, why vegetables are bad for us, and several other questions that he frequently gets asked. 00:10:55 Insulin resistance and how we can be metabolically healthy 00:20:18 Should people with diabetes eat carbs/do glucose levels in the blood matter? 00:22:24 How do we fix diabetes? 00:27:18 Does meat cause cardiovascular disease, gout and cancer? 00:39:35 How did we evolve to eat meat? 00:42:20 What nutrients are missing on a plant-based diet? 00:45:40 Are organs necessary? 00:51:58 Why are vegetables bad for us? 00:59:30 How to construct an animal-based diet 01:01:15 Which blood work should you get? References: Dangers of a keto diet: https://open.spotify.com/episode/5wCsT2K4u6BQ5Y1QUSkTV2?si=7cb47ac1cfaa4c49 Animal-based diet 101: 2023 edition: https://open.spotify.com/episode/3jbxFF4TexuJB9FRmV0bJl?si=2674d60717484768 Bloodwork review: December 2022: https://open.spotify.com/episode/2axxIlqOOkbEikjwJSZ6Qc?si=dbba929199a643f3 Controversial thoughts: Do organ meats cause gout? What does? https://open.spotify.com/episode/0hwJ4dPSrfDySorAvOhRhs?si=e5149cd236694a22 Is all sugar bad for you? High fructose corn syrup vs fruit & honey: https://open.spotify.com/episode/25fC67FMqY4pMHH4XB1Dl9?si=acb47eae3b3f49e8 Sponsors: Heart & Soil: www.heartandsoil.co Carnivore MD Merch: www.kaleisbullshit.shop Make a donation to the Animal Based Nutritional Research Foundation: abnrf.org Animal-based 30 Challenge: https://heartandsoil.co/animalbased30/ Marek Health: marekhealth.com/fundamentalhealth, use code PAUL for 10% off your first lab order and check out Paul’s custom blood panel Joovv Light Therapy: http://joovv.com/paul, use code PAUL for an exclusive discount Zero Acre: www.zeroacre.com/PAUL or use code PAUL for free shipping on your first order Colima Salt: drpaulsalt.com, for a free bag of Colima Sea Salt

On this week’s podcast, Paul has Georgi Dinkov back on the show. They talk about serotonin and the dangers of SSRIs, the downfalls of overexercise, all about gut health, how to tell if your metabolism is working well, other tools to optimize your overall health, and so much more. 00:09:07 How SSRIs affected a crab population, and why serotonin isn’t what we’ve been told 00:18:23 LSD, serotonin, and compliance 00:22:41 What increases serotonin? 00:27:47 Endotoxins’ effect on gut health and intestinal health 00:38:39 Bloodwork that you should consider getting and how to get a sense of your overall metabolic /mental function 00:58:07 Excess estrogen and thymus function 01:08:37 Bioavailability of eating organs and stearic acid 01:17:43 Additives that may irritate the intestines References: Connect with Georgi at http://haidut.me/ Sponsors: Heart & Soil: www.heartandsoil.co Carnivore MD Merch: www.kaleisbullshit.shop Make a donation to the Animal Based Nutritional Research Foundation: abnrf.org Animal-based 30 Challenge: https://heartandsoil.co/animalbased30/ Colima Salt: drpaulsalt.com, for a free bag of Colima Sea Salt Sacred Hunting: sacredhunting.com/PAUL, get $250 off your hunt Our Sponsor LetsGetChecked: 20% off your order at www.TRYLGC.com/paulsaladino for 25% off

In today’s podcast, Paul talks all about sugar, and why all sugar is not created equally. He talks about the benefits of including carbohydrates in your diet via honey, maple syrup, and fruit, especially if you are a recovering keto or carnivore dieter. He then dives deep on refined sugar, specifically high fructose corn syrup, and why you should avoid those at all costs. 00:09:30 Podcast begins 00:11:37 When is a ketogenic diet helpful and what happens when you reintroduce carbs? 00:15:27 Why you should include carbs in your diet 00:20:47 High fructose corn syrup versus table sugar 00:25:17 Electrolyte issues with keto and carnivore 00:27:13 The problems with keto 00:34:37 What kinds of carbohydrates should we include in our diet? 00:37:37 Can diabetics and obese people eat honey? 00:45:27 The concerns about starches 00:51:17 The dangers of high fructose corn syrup Sponsors: Heart & Soil: www.heartandsoil.co Carnivore MD Merch: www.kaleisbullshit.shop Make a donation to the Animal Based Nutritional Research Foundation: abnrf.org Animal-based 30 Challenge: https://heartandsoil.co/animalbased30/ Marek Health: https://marekhealth.com/carnivoremd, use code PAUL for 10% off your first lab order and check out Paul’s custom blood panel Zero Acre: www.zeroacre.com/PAUL or use code PAUL for free shipping on your first order Eight Sleep: www.eightsleep.com/carnivoremd to get $150 off your order Bon Charge: boncharge.com, use code CARNIVOREMD for 15% off your order References: Insulin's impact on renal sodium transport and blood pressure in health, obesity, and diabetes Dietary macronutrient content alters cortisol metabolism independently of body weight changes in obese men Ketosis Leads to Increased Methylglyoxal Production on the Atkins Diet Oxidative stress and aging: Is methylglyoxal the hidden enemy? Effects of natural honey consumption in diabetic patients: an 8-week randomized clinical trial Effects of Daily Consumption of Honey Solution on Hematological Indices and Blood Levels of Minerals and Enzymes in Normal Individuals A Review on the Protective Effects of Honey against Metabolic Syndrome Honey and cardiovascular risk factors, in normal individuals and in patients with diabetes mellitus or dyslipidemia Ruminal lipopolysaccharide concentration and inflammatory response during grain-induced subacute ruminal acidosis in dairy cows Rumen lipopolysaccharide and inflammation during grain adaptation and subacute ruminal acidosis in steers High Fructose Corn Syrup Questions and Answers Carbohydrate Analysis of High Fructose Corn Syrup (HFCS) Containing Commercial Beverages High-fructose corn syrup causes characteristics of obesity in rats: increased body weight, body fat and triglyceride levels Effects of high fructose corn syrup on intestinal microbiota structure and obesity in mice Mercury from chlor-alkali plants: measured concentrations in food product sugar

On this week’s podcast, Paul is responding to claims that some of the information he shares on Instagram is “partial misinformation.” He is going to dismantle the independent fact checker article piece by piece, explaining not only why seed oils are indeed harmful for humans, but also why this kind of censorship is dangerous for our health environment. 00:08:07 Podcast begins 00:12:33 A breakdown of Paul’s Instagram reel that got censored 00:19:24 Paul fact-checks the fact-checkers 00:25:19 Seed oils are harmful to humans 00:32:29 Why do seed oils lower LDL? 00:34:57 Oxidized LDL 00:42:32 The research and researchers behind the claims that seed oils are not harmful 00:57:27 Summary Sponsors: Heart & Soil: www.heartandsoil.co Carnivore MD Merch: www.kaleisbullshit.shop Make a donation to the Animal Based Nutritional Research Foundation: abnrf.org Animal-based 30 Challenge: https://heartandsoil.co/animalbased30/ Sacred Hunting: sacredhunting.com/PAUL, get $250 off your hunt Colima Salt: drpaulsalt.com, for a free bag of Colima Sea Salt Our Sponsor LetsGetChecked: 20% off your order at www.TRYLGC.com/paulsaladino for 25% off

Paul talks about artificial sweeteners (Stevia, Sucralose, Aspartame) in this episode and how they appear to disrupt our guts, and impair glucose tolerance in both animal models and humans. He reiterates why he believes you should not fear sugar in the form of fruit, honey, and maple syrup and why adding carbohydrates to your diet is optimal. 00:09:47 Podcast begins 00:10:47 High fructose corn syrup vs. low-processed sugar (learn more on Paul’s interview with Georgi Dinkov) 00:13:12 Should diabetics consume sugar? 00:25:42 Reintroducing glucose after a ketogenic or carnivore diet 00:28:32 Glycemic index and longevity 00:30:27 Benefits of carbohydrates 00:40:12 What are artificial sweeteners? 00:43:02 The case against artificial sweeteners (Stevia) 00:46:42 The case against artificial sweeteners (Sucralose/Aspartame) 00:59:52 Recapping the podcast Sponsors: Heart & Soil: www.heartandsoil.co Carnivore MD Merch: www.kaleisbullshit.shop Make a donation to the Animal Based Nutritional Research Foundation: abnrf.org Animal-based 30 Challenge: https://heartandsoil.co/animalbased30/ Zero Acre: www.zeroacre.com/PAUL or use code PAUL for free shipping on your first order Eight Sleep: www.eightsleep.com/carnivoremd to get $150 off your order Marek Health: https://marekhealth.com/carnivoremd, use code PAUL for 10% off your first lab order and check out Paul’s custom blood panel Bon Charge: boncharge.com, use code CARNIVOREMD for 15% off your order

Paul explains everything you need to know about an animal-based diet and why this diet is the optimal starting point for humans. He gives you 4 simple steps for things to remove from you diet, and 4 simple steps for things to add to your diet. He does a deep dives about the harm of high fructose corn syrup and artificial sweeteners. 00:07:53 Podcast begins 00:11:53 How do we create health within humans with diet? 00:17:53 What is an animal-based diet? 00:19:53 Improve your diet in 4 removal steps 00:20:43 Why to cut out seed oils 00:24:13 Why to remove high-fructose corn syrup 00:28:23 Why to remove artificial sweeteners 00:34:18 Benefits of removing vegetables from your diet 00:37:13 Add these 4 things to improve your diet 00:37:43 Add organs to your diet 00:40:46 The importance of high quality meat in your diet 00:43:18 The importance of eating carbohydrates 00:46:28 Get your fat from animal fats 00:49:43 Recap of animal-based Sponsors: Heart & Soil: www.heartandsoil.co Carnivore MD Merch: www.kaleisbullshit.shop Make a donation to the Animal Based Nutritional Research Foundation: abnrf.org Animal-based 30 Challenge: https://heartandsoil.co/animalbased30/ Sacred Hunting: sacredhunting.com/PAUL, get $250 off your hunt Joovv Light Therapy: http://joovv.com/paul, use code PAUL for an exclusive discount Our Sponsor LetsGetChecked: 20% off your order at www.TRYLGC.com/paulsaladino for 25% off

In today’s episode, Paul summarizes his favorite episodes from 2022. He gives a high level summary of the topics, as well as provides episode titles and numbers for you to hear more if you so wish. Time Stamps: 00:06:15 Podcast begins 00:07:29 Episode 148: The Blue Zones are BS 00:13:52 Episode 187: Meats vs. plants for longevity 00:16:23 Episode 153: Is fruit good or bad for humans? 00:17:23 The benefits of fruit and honey (Episode 189 with Ken Berry, Episode 173 with Thomas DeLauer, Episode 172: The dangers of a ketogenic diet) 00:23:18 Episode 159: What is an animal-based diet? 00:27:08 Episode 155: How to maximize testosterone 00:29:48 Episode 171: July bloodwork, Episode 179: August bloodwork, Episode 193: December bloodwork 00:36:16 Episode 156: Paul’s perspective on mental health 00:41:19 Episode 178: LDL Cholesterol, Episode 190: Interview with Cardiologist Mike Twyman 00:43:08 Episode 183: Pharma corruption with John Abramson 00:45:13 Episode 170: How to fix your gut 00:47:43 Episode 194 Interview with Gerogi Dinkov on the harm of corn starch, corn syrup and seed oils 00:53:13 Episode 192: What Paul eats in a day via Cronometer 00:54:38 Episode 180: How to lose weight 00:56:28 Episode 194: Interview with Gerogi Dinkov about Ray Peat diet Sponsors: Heart & Soil: www.heartandsoil.co Animal-based 30 Challenge: https://heartandsoil.co/animalbased30/ Colima Salt: drpaulsalt.com, for a free bag of Colima Sea Salt Shirttail Creek Farm: shirttailcreekfarm.com, use code CarnivoreMD20 for $20 off order of $100 or more Bon Charge: https://boncharge.com, use code CARNIVOREMD for 15% off your order, or, from 12/26-1/2 get 25% off sitewide

In today’s episode, Paul chats with Bioenergetic Health researcher, Georgi Dinkov. They jump down the rabbit hole on a myriad of topics, including the distinction between table sugar and high-fructose corn syrup, how starch damages the gut, polyunsaturated fatty acids, sunlight, emfs and more. Sit back, relax and put on your open-minded thinking cap–you might learn a thing or two. 00:11:05 Sucrose vs. high fructose corn syrup 00:26:35 The link between food, stress hormones, and mental disorders 00:35:35 Thoughts on ketogenic diets 00:43:50 Should we limit our carb intake? 00:52:13 How to test cortisol and other hormones 00:56:30 How hormones and genetics play a role in metabolizing sugar 1:00:02 The Randle Cycle 1:08:08 Low fat vs. high fat diets 01:16:05 Exhaustive exercise 01:27:28 A deep dive into serotonin & SSRIs 01:48:40 Why to avoid starchy foods 01:51:25 The importance of organs 02:06:55 Where to find Georgi’s content *Salaryman Documentary * Sponsors: Heart & Soil: www.heartandsoil.co Carnivore MD Merch: www.kaleisbullshit.shop Make a donation to the Animal Based Nutritional Research Foundation: abnrf.org Animal-based 30 Challenge: https://heartandsoil.co/animalbased30/ White Oak Pastures: www.whiteoakpastures.com, use code CarnivoreMD for 10% off your first order or Carnivore5 for 5% off subsequent orders Our Sponsor LetsGetChecked: 20% off your order at www.TRYLGC.com/paulsaladino for 25% off Colima Salt: drpaulsalt.com, for a free bag of Colima Sea Salt Marek Health: marekhealth.com/fundamentalhealth, use code PAUL for 10% off your first lab order

On this week’s podcast, Paul takes you through his most recent blood work from November 2022, alongside his genetic results, as well as an abbreviated version of what he eats in a day. He talks about how his levels have changed since his previous bloodwork and, specifically, what he implemented to get his free testosterone up, and his sex-hormone binding globulin down. He clearly shows his transparent bloodwork to indicate that he has not, and does not, take any performance enhancing drugs. A note from Paul: Throughout my training and practice as a physician I have come to one very disappointing conclusion:  Western medicine isn’t helping people lead better lives. Now that I’ve realized this, I’ve become obsessed with understanding what makes us healthy or ill. I want to live the best life I can and I want to be able to share this knowledge with others so that they can do the same. This podcast is the result of my relentless search to understand the roots of chronic disease. If you want to know how to live the most radical life possible I hope you’ll join me on this journey. Time Stamps: 00:08:26 Podcast begins 00:13:69 Paul’s bloodwork (Testosterone) 00:18:06 Lowering his SHBG and Iron Labs 00:26:09 Paul’s genetics 00:28:29 APOE44- How does this affect longevity? 00:37:015 The importance of the thyroid 00:38:59 CBC results 00:42:11 Urinalysis results 00:43:39 Cholesterol results 00:44:39 More bloodwork results and what levels look like if someone is taking growth hormones 00:50:06 Cronomoter breakdown of a day of Paul’s food consumption 00:54:15 What labs should you get? Sponsors: Heart & Soil: www.heartandsoil.co Carnivore MD Merch: www.kaleisbullshit.shop Make a donation to the Animal Based Nutritional Research Foundation: abnrf.org White Oak Pastures: www.whiteoakpastures.com, use code CarnivoreMD for 10% off your first order or Carnivore5 for 5% off subsequent orders Bon Charge: https://boncharge.com, use code CARNIVOREMD for 15% off your order Colima Salt: drpaulsalt.com, for a free bag of Colima Sea Salt Shirttail Creek Farm: shirttailcreekfarm.com, use code CarnivoreMD20 for $20 off order of $100 or more