
Paul Saladino MD podcast
Throughout my training and practice as a physician I have come to one very disappointing conclusion: Western medicine isn’t helping people lead better lives. Now that I’ve realized this, I’ve become obsessed with understanding what makes us healthy or ill. I want to live the best life I can and I want to be able to share this knowledge with others so that they can do the same. This podcast is the result of my relentless search to understand the roots of chronic disease. I hope you’ll join me on this journey.
Latest episodes

Aug 29, 2023 • 1h 2min
230. Is fruit juice healthy?
This podcast explores the controversial topic of fruit juice and argues in favor of including it in a diet. They address concerns about glucose spikes, insulin resistance, and the benefits of carbohydrates, discussing studies on fruit juice and its impact on cardiovascular health, antioxidant status, and cognitive function. The podcast also explores the role of carbohydrates in hormonal health, libido, and sleep, and challenges misconceptions about blood glucose spikes and weight gain/diabetes.

6 snips
Aug 21, 2023 • 53min
229. Is hair loss reversible?
The podcast discusses the link between hair loss and nutrient deficiencies, different types of hair loss, concerns with mainstream treatment methods, and the role of nutrients in hair regrowth. It explores anecdotes of hair regrowth, the connection between diet and hair loss, nutrient deficiencies that may lead to hair loss, concerns with biotin, and testosterone lowering foods to avoid.

21 snips
Aug 15, 2023 • 2h 2min
228. Cholesterol debate with Dr. Alo
Dr. Paul brings on Dr. Mohammad Alo, a cardiologist and personal trainer, to discuss the cholesterol debate. They explore topics such as cardiovascular risk, insulin resistance, metabolic health of Americans, LDL and atherosclerosis, fasting insulin, arteries and veins, genes and lifestyles, seed oils versus saturated fat, and the problems with totality of evidence.

Aug 8, 2023 • 1h 12min
227. Kneesovertoesguy reveals his diet secrets
Ben Patrick, the 'Knees Over Toes Guy,' reveals his diet secrets in a conversation with Paul Saladino. They discuss optimal health, out-of-the-box exercise, muscle-building, toxin exposure, fitness principles, and the importance of raw dairy and organ meats. They also delve into strengthening the shoulder and share details about Ben's upcoming projects, including opening a school.

Aug 1, 2023 • 1h
226. Eating meat reverses aging
In today’s podcast, Paul unpacks the myth that eating red meat is counterproductive to longevity. He explains all of the unique nutrients found in red meat, how much red meat he believes we need, and why he believes that red meat in fact reverses aging.
00:11:35 Mainstream view of red meat & the problem with epidemiology studies
00:19:35 Unique nutrients in red meat
00:30:30 Taurine
00:39:05 How much red meat we should be eating
00:43:35 Creatine, carnosine, anserine
00:53:55 The importance of B-12
00:58:10 Conclusion
Sponsors:
Heart & Soil: www.heartandsoil.co
Carnivore MD Merch: www.kaleisbullshit.shop
Make a donation to the Animal Based Nutritional Research Foundation: abnrf.org
Animal Based 30, join the challenge! https://heartandsoil.co/animalbased30/
Marek Health: marekhealth.com/fundamentalhealth, use code PAUL for 10% off your first lab order
Colima Salt: drpaulsalt.com, for a free bag of Colima Sea Salt
Rhizal: https://rhizal.co/, use code PAUL for 10% off your purchase
Joovv Light Therapy: http://joovv.com/paul, use code PAUL for an exclusive discount
References:
Meat & Longevity Podcast: https://www.youtube.com/watch?v=x8GmGIqxA0Q&t=36s
Debuking Common Vegan Arguments Podcast: https://www.youtube.com/watch?v=Q46ca9CQzcE
Cutting red meat-for a longer life: https://www.health.harvard.edu/staying-healthy/cutting-red-meat-for-a-longer-life
Mortality in vegetarians and comparable nonvegetarians in the United Kingdom: https://pubmed.ncbi.nlm.nih.gov/26657045/
Vegetarian diet and all-cause mortality: Evidence from a large population-based Australian cohort - the 45 and Up Study: https://pubmed.ncbi.nlm.nih.gov/28040519/
Meat intake and cause-specific mortality: a pooled analysis of Asian prospective cohort studies: https://pubmed.ncbi.nlm.nih.gov/23902788/
Bryan Johnson Supplements: https://blueprint.bryanjohnson.co/#step-2-supplements
Important roles of dietary taurine, creatine, carnosine, anserine and 4-hydroxyproline in human nutrition and health: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088015/
Taurine deficiency as a driver of aging: https://pubmed.ncbi.nlm.nih.gov/37289866/
Animal-based calculator: https://www.paulsaladinomd.co/ab-guide
Use of creatine in the elderly and evidence for effects on cognitive function in young and old: https://pubmed.ncbi.nlm.nih.gov/21394604/
Dietary Intervention Modifies DNA Methylation Age Assessed by the Epigenetic Clock: https://pubmed.ncbi.nlm.nih.gov/30350398/
The effects of long-term daily folic acid and vitamin B12 supplementation on genome-wide DNA methylation in elderly subjects: https://pubmed.ncbi.nlm.nih.gov/26568774/
B vitamins, homocysteine, and neurocognitive function in the elderly: https://ajcn.nutrition.org/article/S0002-9165(23)07031-4/fulltext
Can Vitamins Slow Down the Body’s Aging Process?: https://kids.frontiersin.org/articles/10.3389/frym.2022.707514

Jul 25, 2023 • 1h 16min
225. Heal your gut with RAW MILK: a conversation with Mark McAfee from Raw Farm
In this week’s podcast, Paul sits with Mark McAfee on the largest raw dairy farm in the world, RAW Farm. They talk about about Mark’s process of raising and caring for cattle that produces clean, safe raw milk, the overall benefits of raw milk and colostrum in terms of gut health, and why we should “make milk RAW again!”
00:09:08 Beneficial bacteria in milk & kefir
00:11:13 The history of pasteurization in America
00:18:18 Benefits of breastfeeding (mammalian milk)
00:27:38 Germ theory & terrain theory
00:29:38 The role of raw milk & colostrum
00:36:38 The origins of RAW farm
00:42:18 Comparing dairy farms production methods
00:45:08 Why isn’t raw milk legal everywhere?
00:48:53 The milk barn story
00:51:18 The process of making RAW cheese & the importance of bacteria
01:12:08 Benefits of butter and milk fat
References:
British Columbia Herdshare Association: bcherdshare.org/
Sponsors:
Heart & Soil: www.heartandsoil.co
Carnivore MD Merch: www.kaleisbullshit.shop
Make a donation to the Animal Based Nutritional Research Foundation: abnrf.org
Schwank Grills: schwankgrills.com, use code PAUL150 for $150 off a Schwank 1500 degree grill
Earth Runners: www.earthrunners.com, use code CARNIVORE for 10% off your order
Bon Charge: boncharge.com, use code CARNIVOREMD for 15% off your order

19 snips
Jul 18, 2023 • 1h 32min
224. The skincare industry hates this
This week, Paul is reposting his debut on The Skinny Confidential Podcast. Lauren and Michael, the hosts of the show, ask Paul about animal-based eating for optimal health, beef tallow as skincare, questions about what kind of milk to consume, and why vegans may be more similar to animal-based eaters than we may think.
00:06:45 Animal-based during pregnancy
00:08:10 Informing vegans about eating animals
00:12:45 Paul’s background in root cause medicine
00:17:40 The “perfect poop”
00:20:35 Why to reincorporate meat into your diet
00:23:50 Ethics, environmentalism, and veganism
00:31:40 How a vegan may incorporate meat
00:35:20 What to look for when buying meat
00:40:20 Almond milk vs. raw milk
00:49:30 Phthalates & PFAs
00:55:00 Switching from carnivore to animal-based
01:01:20 Weight loss with animal-based
01:06:00 A day in the life in Costa Rica
01:15:00 Seed oils vs. tallow
01:25:00 Protein intake
Sponsors:
Heart & Soil: www.heartandsoil.co
Carnivore MD Merch: www.kaleisbullshit.shop
Make a donation to the Animal Based Nutritional Research Foundation: abnrf.org
Rhizal: https://rhizal.co/, use code PAUL for 10% off your purchase
Joovv Light Therapy: http://joovv.com/paul, use code PAUL for an exclusive discount
Calima Salt: drpaulsalt.com, for a free bag of Calima Sea Salt
Marek Health: marekhealth.com/fundamentalhealth, use code PAUL for 10% off your first lab order

6 snips
Jul 11, 2023 • 57min
223. Oatmeal is NOT a health food
Have you been led to believe that oatmeal is good for you? This podcast is for you! Paul does a deep dive on why you may want to cut oats (and chocolate, and leafy greens) out for good for reasons like heavy metal accumulation, antinutrients, and defense chemicals.
00:07:30 The problem with grains
00:11:45 Heavy metals in oats, greens, chocolate and fish
00:20:00 How saponins damage the gut
00:31:30 Cadmium and heavy metals in oats, vegetables and chocolate
00:48:15 Phytic acid
00:49:20 Pesticides in your oats
00:50:50 Mold contamination in grains
00:53:00 Takeaways on oats
References:
Influence of saponins on gut permeability and active nutrient transport in vitro: https://www.semanticscholar.org/paper/Influence-of-saponins-on-gut-permeability-and-in-Johnson-Gee/b100e152961fa3beb84c676ac0ae43e74b52af9e
Reducing the damage of quinoa saponins on human gastric mucosal cells by a heating process: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977518/
Triterpenoid Saponins in Oat Bran and Their Levels in Commercial Oat Products: https://figshare.com/collections/Triterpenoid_Saponins_in_Oat_Bran_and_Their_Levels_in_Commercial_Oat_Products/5002223
The biological action of saponins in animal systems: a review: https://pubmed.ncbi.nlm.nih.gov/12493081/
Effect of oat saponins and different types of dietary fibre on the digestion of carbohydrates: https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/effect-of-oat-saponins-and-different-types-of-dietary-fibre-on-the-digestion-of-carbohydrates/95992869AEC98CFAB161548C043F93E7
Effects of saponins and glycoalkaloids on the permeability and viability of mammalian intestinal cells and on the integrity of tissue preparations in vitro: https://pubmed.ncbi.nlm.nih.gov/20650190/
A major gene for grain cadmium accumulation in oat (Avena sativa L.): https://www.researchgate.net/publication/6204970_A_major_gene_for_grain_cadmium_accumulation_in_oat_Avena_sativa_L
Toxicity of cadmium and its health risks from leafy vegetable consumption:https://www.researchgate.net/publication/313975727_Toxicity_of_cadmium_and_its_health_risks_from_leafy_vegetable_consumption
Ideal Cereals With Lower Arsenic and Cadmium by Accurately Enhancing Vacuolar Sequestration Capacity: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467212/
Cadmium Levels in Soils and Crops in the United States: https://www.semanticscholar.org/paper/Cadmium-Levels-in-Soils-and-Crops-in-the-United-Chang-El-Amamy/18c4415de7340ae4b30ac9516c1acae4c4ed6300
Sponsors:
Heart & Soil: www.heartandsoil.co
Carnivore MD Merch: www.kaleisbullshit.shop
Make a donation to the Animal Based Nutritional Research Foundation: abnrf.org
Bon Charge: boncharge.com, use code CARNIVOREMD for 15% off your order
Zero Acre: www.zeroacre.com/PAUL or use code PAUL for free shipping on your first order
Earth Runners: www.earthrunners.com, use code CARNIVORE for 10% off your order

Jul 4, 2023 • 2h 2min
222. Are Snickers bars fruit? With Aaron Alexander
Today’s episode features Paul on the Align podcast with Aaron Alexander. They chat about a plethora of topics, beginning with cholesterol, touching on seed oils, testicular health, sweeteners, and endocrine disrupting chemicals along the way, and ending with a conversation about the importance of social and mental health.
00:07:45 Podcast begins
00:10:00 Clarifying the cholesterol conversation
00:29:45 Hadza diet & movement patterns
00:34:00 Seed oils lowering LDL & the Statin conversation
00:42:40 Testicular health & forever chemicals
00:51:50 Endocrine disrupting chemicals
01:08:20 The importance of social & mental health
01:20:50 Intuitive eating & meat substitutes
01:32:00 Thoughts on different kinds of sweeteners
01:44:30 Canola oil
01:47:45 Why do we fear the sun?
01:56:50 Thoughts on olive oil
Sponsors:
Heart & Soil: www.heartandsoil.co
Carnivore MD Merch: www.kaleisbullshit.shop
Make a donation to the Animal Based Nutritional Research Foundation: abnrf.org
Zero Acre: www.zeroacre.com/PAUL or use code PAUL for free shipping on your first order
Joovv Light Therapy: http://joovv.com/paul, use code PAUL for an exclusive discount
Sacred Hunting: sacredhunting.com/PAUL, get $250 off your hunt
Marek Health: https://marekhealth.com/fundmental-health-collection/, or use code PAUL for 10% off your first lab order and check out Paul’s custom blood panel

Jun 26, 2023 • 1h
221. How to optimize sleep
Paul’s episode today is all about sleep. He touches on substances like caffeine, alcohol, and marijuana, how grounding may impact circadian rhythms, and you’ll get an inside look at Paul’s morning and nighttime routine.
00:09:00 How we view sleep as a society
00:10:30 REM versus nonREM sleep
00:15:30 How much sleep is enough sleep?
00:19:50 Sleeping more = earning more?
21:50 Less sleep = less attractive?
00:25:35 Sleep for athletics and learning
00:27:40 How much/when to sleep
00:31:50 Paul’s sleep routine
00:46:45 Coffee, alcohol and marijuana’s effect on sleep
00:50:07 How to troubleshoot your sleep
00:52:00 Sleep supplements
00:54:40 Blue light’s effect on sleep
00:58:15 Grounding & sleep
References:
https://iristech.co/
Time Use and Productivity: The Wage Returns to Sleep: https://ideas.repec.org/p/wil/wileco/2015-17.html
Partial sleep deprivation reduces natural killer cell activity in humans: https://pubmed.ncbi.nlm.nih.gov/7871104/
Deep Sleep Gives Your Brain a Deep Clean: https://www.scientificamerican.com/article/deep-sleep-gives-your-brain-a-deep-clean1/
Negative effects of restricted sleep on facial appearance and social appeal: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451790/
Blocking nocturnal blue light for insomnia: A randomized controlled trial: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703049/
Smartphone viewing distance and sleep: An experimental study utilizing motion capture technology: https://www.researchgate.net/publication/314716943_Smartphone_viewing_distance_and_sleep_An_experimental_study_utilizing_motion_capture_technology
Amber lenses to block blue light and improve sleep: a randomized trial: https://pubmed.ncbi.nlm.nih.gov/20030543/
Perception of Sleep Disturbances due to Bedtime Use of Blue Light-Emitting Devices and Its Impact on Habits and Sleep Quality among Young Medical Students: https://www.hindawi.com/journals/bmri/2019/7012350/
Blue light from light-emitting diodes elicits a dose-dependent suppression of melatonin in humans: https://pubmed.ncbi.nlm.nih.gov/21164152/
The Biologic Effects of Grounding the Human Body During Sleep as Measured by Cortisol Levels and Subjective Reporting of Sleep, Pain, and Stress: https://www.researchgate.net/publication/8081857_The_Biologic_Effects_of_Grounding_the_Human_Body_During_Sleep_as_Measured_by_Cortisol_Levels_and_Subjective_Reporting_of_Sleep_Pain_and_Stress
Sponsors:
Heart & Soil: www.heartandsoil.co
Carnivore MD Merch: www.kaleisbullshit.shop
Make a donation to the Animal Based Nutritional Research Foundation: abnrf.org
Schwank Grills: schwankgrills.com, use code PAUL150 for $150 off a Schwank 1500 degree grill
Earth Runners: www.earthrunners.com, use code CARNIVORE for 10% off your order
Eight Sleep: $150 off the PodPro cover at www.eightsleep.com/carnivoremd
Bon Charge: boncharge.com, use code CARNIVOREMD for 15% off your order