In this engaging conversation, Dr. Justin Ichida, an assistant professor at the University of Southern California, shares his pioneering work on direct reprogramming to study neurodegenerative diseases. He dives into innovative techniques for converting skin cells into neurons, aiming to unravel the mysteries of ALS and frontotemporal dementia. The discussion also covers intriguing advancements in biotechnologies, including the ethical implications of cloning and the significance of patient-specific models in understanding neuronal loss.

Join Dr. Paul Knoepfler, an influential associate professor at UC Davis, as he dives into the controversial world of STAP stem cells. He sheds light on the challenges of replicating this groundbreaking method for generating pluripotent cells. The discussion also touches on the emotional connections in the animal kingdom and the groundbreaking implications of stem cells for autism and neural repair. With a mix of humor and critical insights, Dr. Knoepfler highlights the importance of transparency in stem cell research, all while educating audiences through his popular blog.

Dr. Sean Morrison, a renowned professor and director at UT Southwestern, shares his insights on the intricate relationship between stem cells and cancer. He discusses the pivotal role of cancer stem cells in tumor behavior and the challenges in distinguishing between tumorigenic and non-tumorigenic cells. The conversation takes a captivating turn with anecdotes about the bizarre world of 'zombie bees' and breakthroughs in generating pluripotent stem cells through unique methods. Dr. Morrison's expertise brings light to the future of cancer treatment and stem cell research.

Dr. Mark Tomishima, director of the SKI Stem Cell Research Facility in NYC, shares insights into the crucial role of stem cell core facilities in advancing research. He discusses groundbreaking projects like creating organoid kidney structures and the ethical considerations of stem cell therapy, including immune rejection challenges. The conversation also highlights exciting advancements such as gene editing technologies and the progress of placenta-derived stem cells. Get ready for a blend of science and humor that showcases the collaborative spirit in the stem cell research community!

Dr. Sally Temple, scientific director of the Neural Stem Cell Institute, is a trailblazer in neural stem cell research. She discusses her groundbreaking discovery of a novel stem cell in the eye that holds promise for treating macular degeneration, the leading cause of blindness. The conversation also delves into the emotional impact of losing vision versus hearing and highlights the challenges gender disparity poses within the scientific community. Finally, they touch on innovative techniques in RPE cell research and preparations for future clinical trials.

Happy new year Stem Cell Podcast listeners, we are back to start off with an episode that looks backs at a year of science in 2013 and gives you our top 10 studies from both the stem cell world and science as a whole. We discuss a variety of topics from human cloning to going interstellar. It's been a great year for science despite threats to funding. Let's make sure science funding increases in 2014. Enjoy! Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Justine Miller, a PhD candidate from Lorenz Studer's lab at Memorial Sloan Kettering, discusses her groundbreaking research on aging neurons derived from stem cells. She reveals how they age in culture, shedding light on neurodegeneration and the challenges in modeling such diseases. The conversation touches on innovative gene editing techniques like CRISPR and the implications of recent findings on male birth control. Join them as they explore the intersection of neuroscience, aging, and cutting-edge research methodologies.

Get ready for a holiday science treat! Dive into fascinating topics like the biology behind our fear of snakes, the connection between genes and Alzheimer's, and shocking findings from the mummified past. Discover groundbreaking advancements in stem cell research, including potential treatments for ALS. Plus, hear about the cosmic wonders like gamma-ray bursts and the rising threat of resistant bacteria in hospitals. It's a mix of light-hearted banter and serious science that’s sure to intrigue!

Dr. Asif Maroof, a post-doctoral fellow at the Harvard Stem Cell Institute specializing in ALS, delves into groundbreaking research on the C9orf72 gene linked to the neurodegenerative disease. He shares insights on how this gene affects motor neuron health and disease progression, shedding light on ALS's complexities. The discussion also touches on the importance of community engagement in scientific research, and the potential of cell-based therapies in treating neurological conditions. Expect fascinating nuggets about genetics and global health along the way!

Delve into the complexities of Parkinson's disease, including its historical context and the vital role of dopamine neurons. Discover the promising potential of stem cell therapy, including advanced techniques in neuron generation and the ethics surrounding fetal tissue. The discussion also sheds light on recent innovations, from deep brain stimulation to the significant impact of the microbiome on neurological health. Plus, enjoy some light-hearted lab anecdotes about the trials of pipette usage!