Ep. 31: Cell Stem Cell Editor featuring Dr. Christina Lilliehook
Nov 11, 2014
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Dr. Christina Lilliehook, Senior Editor at Cell Stem Cell, shares her journey in scientific editing and reveals the behind-the-scenes process of handling manuscripts. She discusses intriguing topics like a unique brain surgery that cured a man’s fear of spiders and sheds light on the complex development of penises in evolutionary biology. Dr. Lilliehook also dives into the challenges of peer review, the need for broad reading, and the importance of maintaining research integrity in the ever-evolving landscape of scientific publishing.
Dr. Christina Lilleyhook provides insight into the rigorous editorial process at Cell Stem Cell, emphasizing collaboration and constructive feedback among the editorial team.
The podcast highlights the evolving trends in stem cell research, particularly the growing focus on iPSCs, which shapes editorial strategies and topics of interest.
Challenges in maintaining integrity in scientific publishing have led editors to adopt stricter measures against data manipulation, ensuring trust and credibility.
Deep dives
Introduction to the Editorial Process
The podcast features an interview with Dr. Christina Lilleyhook, a senior editor at Cell Stem Cell, who provides insight into the editorial process within scientific publishing. She explains that upon submission, a manuscript is assigned to a handling editor who thoroughly reviews it and ensures it aligns with the journal's standards. This editor then collaborates with the editorial team to summarize the paper and determine if it should proceed to peer review. The editorial team aims to provide constructive feedback, emphasizing a collaborative rather than authoritarian approach.
Trends in Stem Cell Research
Dr. Lilleyhook shares her experiences observing trends in stem cell research through the influx of submissions over the years. She notes that there have been periods of increased focus on specific topics, such as induced pluripotent stem cells (iPSCs) and direct reprogramming, indicating a dynamic evolution in the field. This observation allows editors to identify emerging trends and advancements in research, which shapes their editorial strategies and topics of interest. The realization of shifts in research focus enables journals to adapt and cater to the changing landscape of scientific inquiry.
Collaborative Review Process
The podcast discusses the importance of multidisciplinary collaboration in the review process, particularly for studies that incorporate various scientific fields. Dr. Lilleyhook mentions that editors strive to select reviewers with relevant expertise to accurately assess the work presented in a manuscript. However, this can present challenges, as it is often difficult to find experts that cover all necessary aspects of a complex study. The editorial team sometimes faces the task of reconciling differing expert opinions and synthesizing their feedback to ensure fair and thorough evaluations.
Challenges in Scientific Publishing
The conversation also addresses the challenges associated with maintaining integrity and quality in scientific publishing, especially in light of retractions and controversies in the field. Dr. Lilleyhook explains that while editors traditionally operate on a principle of trust toward authors, the recent rise in public scrutiny has led to a more heightened awareness of potential data manipulation. Editors are now more vigilant in assessing the scientific validity of submissions, seeking to implement strategies to catch fraudulent practices early in the review process. This shift reflects an evolving landscape where maintaining credibility is paramount in the scientific community.
Future Directions in Stem Cell Research
The podcast concludes with insights into the future of stem cell research, specifically regarding clinical applications and trials. Dr. Lilleyhook expresses optimism about ongoing iPSC trials, particularly in retinal disease, seeing them as a potential turning point for therapeutic advancements. She emphasizes the importance of addressing neurological conditions and how companies are actively progressing in this area. The discussion reinforces the excitement surrounding stem cell research and the prospect of tangible benefits for patient care in the near future.
Guest:
Senior editor at Cell Stem Cell, Dr. Christina Lilliehook shares with us what goes on as an editor of a top tier science journal. In addition to a behind the scenes discussion, she also talks about how she got into a career in editing, and what it takes if you wanted to make that career choice.
Resources and Links
Arachnophobia Gets Cut Out of Man’s Brain after Surgery to End His Seizures – This article discussed an instance where an unrelated seizure forced doctors to remove a portion of a man's brain, inadvertently freeing him of his fear of spiders.
Mystery Solved: Where the Penis Comes From – This article attempts to answer a question a lot of scientists ponder out loud that is key to much of life on Earth: Exactly how does the penis form?
Plasticity of the Aging Brain: New Directions in Cognitive Neuroscience – The authors review the two new directions in the field of aging research with implications for plasticity.
Modeling Ebola in Mice – This article is about a study conducted by a team of scientists who have tested 47 genetically diverse mouse lines in response to their susceptibility to Ebola.
Effects of Diurnal Variation of Gut Microbes and High-Fat Feeding on Host Circadian Clock Function and Metabolism – The body’s helpful bacteria may have internal clocks too that when disrupted will potentially boost the risk of obesity.
Dozens of Genes Associated with Autism in New Research – This press release discusses two new studies conducted by UC San Francisco scientists tying mutations in more than 100 genes to autism.
‘Treasure in Saliva’ May Reveal Deadly Diseases Early Enough to Treat Them, UCLA Scientists Report – A simple saliva test is capable of diagnosing early stage diabetes, cancer, and perhaps neurological disorders and autoimmune diseases.
Violence Genes May Be Responsible for One in Ten Serious Crimes – Scientists believe that they have discovered the genes responsible for high levels of rage-related violent behavior.
Jupiter-Sized Sunspot Largest for 24 Years – This article is about the solar eclipse that happened few weeks back, showing large sunspots responsible for creating some pretty stormy space weather.
New Way to Lose Weight: Scientists Stimulate Brown Fat to Burn More Energy from Food – This article shows how scientists have now come closer to the goal of finding an efficient method for losing weight through the body’s own adenosine that activates brown fat and “browns” white fat.
Growth of CH3NH3PbI3 Cuboids with Controlled Size for High-Efficiency Perovskite Solar Cells – Scientists report that the growth of CH3NH3PbI3 cuboids with a controlled size via a two-step spin-coating procedure enables a power conversion efficiency of perovskite solar cells to exceed 16%.
Stem Cell Person of the Year 2014: Masayo Takahashi – This article announces Dr. Masayo Takahashi MD, PhD as the winner of the 2014 Stem Cell Person of the Year Award.
Stem Cell Patent to Reach Supreme Court – The U.S. Supreme Court will be asked to intervene over a controversial embryonic stem cell patent according to the opponents of the patent.
Managers of Discredited STAP Stem Cell Study Refund Salary – The top administrators of RIKEN, Japan’s national network of research laboratories will voluntarily return one to three months of their salaries to atone for their responsibility for the STAP stem cell fiasco.
Breast Milk Stem Cells May Be Incorporated into Baby – This article suggests that breast milk stem cells from mum could possibly go on to transform into parts of the baby’s body.
Modeling Human Development and Disease in Pluripotent Stem-cell-derived Gastric Organoids – The authors describe a new and robust in vitro system for elucidating the mechanisms underlying human stomach development and disease.
Destroying Brain Tumors Using Herpes-loaded Stem Cells – Scientists from the Harvard Stem Cell Institute may have a potential solution for how to more effectively kill tumor cells using cancer-killing viruses.
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