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The Stem Cell Podcast

Ep. 32: Parkinson’s Cell Therapy Featuring Dr. Malin Parmar

Nov 25, 2014
Dr. Malin Parmar, an Associate Professor at Lund University, pioneers research on stem cell therapies for Parkinson's disease. She discusses her groundbreaking paper published in Cell Stem Cell, which has drawn significant media attention. The conversation delves into innovative strategies like in vivo reprogramming to transform glial cells into dopamine neurons for treatment. Parmar emphasizes collaboration in research and highlights the challenges and successes within the field, providing fascinating insights into the potential future of Parkinson's therapies.
01:12:11

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Quick takeaways

  • Recent advances in stem cell research enable the transformation of embryonic stem cells into functional dopamine neurons, crucial for Parkinson's disease treatment.
  • Increasing the yield of functional dopamine neurons from stem cells can enhance the feasibility of clinical applications for Parkinson's therapy.

Deep dives

Exploring Cell Therapy for Parkinson's Disease

Cell therapy is being researched as a potential approach to address motor deficits in individuals with Parkinson's disease. The discussion highlights the recent advancements made in transforming human embryonic stem cells into functional dopamine neurons, which are crucial for motor control and are lost in Parkinson's patients. Researchers are excited about the implications of using stem cell-derived dopamine neurons compared to traditional fetal dopamine cells. Ultimately, this could lead to new therapeutic options for restoring dopamine function in the affected brain regions.

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