The Metabolic Link

We’ve just launched an extra and exciting episode of The Metabolic Link podcast! It features an eye-opening conversation between our host Dominic D’Agostino PhD, and guests Dave Feldman and Dr. Nick Norwitz, two researchers and MHS 2024 speakers spearheading investigations into the lean mass hyperresponder (LMHR) phenotype.Dave Feldman is a software engineer who became deeply interested in lipidology after seeing his cholesterol spike on a low-carb, high-fat diet. He has since performed self-experiments and published several papers on the possible mechanisms behind LMHR. He is currently conducting a clinical study out of UCLA through his newly formed public charity, the Citizen Science Foundation.Nicholas Norwitz completed his PhD at the University of Oxford and his thesis focused on ketone metabolism and neurodegenerative diseases. He is currently a medical student at Harvard Medical School.In this episode Dave, Dr. Norwitz, and Dr. D'Agostino dive into…The debate around whether saturated fat drives increased LDL levels, especially in the LMHR phenotype.The "Lipid Energy Model" hypothesizing a metabolic/physiological process underlying LMHR phenotype. Concerns about erroneously grouping lean mass hyperresponders with familial hypercholesterolemia patients. The importance of separating discussions of underlying mechanism from clinical recommendations.Their vision for the future direction of LMHR research and public education on this topic.Be sure to secure your spot at MHS 2024 in Clearwater Beach, Florida, where Dave and Nick will be presenting their latest research! Both virtual and in-person seats are still available at metabolichealthsummit.com.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

This week’s episode of The Metabolic Link features an illuminating conversation between our host Dr. Dominic D’Agostino and Dr. Jonathan Jun, a pulmonary critical care and sleep medicine physician at Johns Hopkins.He is an expert in the diagnosis and treatment of sleep-disordered breathing, and in the care of critically ill patients in the Medical ICU. He is a member of the Sleep Fellowship Program Evaluation and Clinical Competency Committee and provides teaching to medical students and residents at Johns Hopkins.In this episode, we cover:💡 Defining obesity hypoventilation syndrome (OHS) and its overlap with sleep apnea💡 Assessing CO2 retention and implementing non-invasive ventilation💡 The role of dramatic weight loss in treating OHS💡 Using ketogenic diets to lower CO2 levels and improve sleep apnea💡 Developing pharmacological options for OHS and sleep disordered breathing💡 Studying the impacts of exogenous ketones ingestion prior to sleepBe sure to secure your spot at MHS 2024 in Clearwater Beach, Florida as Dr. Jun will be joining us to present more of his research! CMEs and CPEUs available. Virtual registration is also an option for those who can’t join us in person! Go to metabolichealthsummit.com to learn more.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Discover the metabolic wonders of allulose, a low-calorie sweetener that supports insulin sensitivity and aids weight management. The hosts highlight how allulose might revolutionize dietary approaches for diabetes and metabolic disorders. They dive into the alarming links between fructose and cancer progression, discussing how high fructose intake fuels tumors and triggers obesity-related risks. The conversation emphasizes dietary fructose restriction as a potential anti-cancer measure, all while underscoring the need for further research in these critical areas.

Entrepreneur Chad Vanags shares his journey of becoming metabolically, physically, and mentally elite to heal from cancer. They discuss the stress-health connection, the motivation gap in cancer patients, and navigating a diagnosis with mental resilience. They also touch on the role of nutrition and mindset in mental health, as well as overcoming fear and transitioning to a new venture.

Registered dietitian Franziska Spritzler discusses tools for low-carb diets, managing blood work, tips for eating out, views on sweeteners, and involving the family. She emphasizes individual variation, tracking food intake, health optimization, and strategies for dining out. Excitement about metabolic health growth and plans for future research.

Discussions on the potential of low-carb and ketogenic diets for treating mood and anxiety disorders. Exploration of mindfulness-based interventions for psychiatric disorders and their efficacy. Emphasis on the need for more research and lifestyle approaches to positively impact mental health. Highlight of the emerging science linking metabolic function to brain health and psychiatric wellbeing.

This week’s episode of The Metabolic Link features an illuminating conversation between our host Dr. Dominic D'Agostino and Dr. Kyle Gillett, a board-certified physician in family and obesity medicine who provides holistic care to his patients.He earned his medical degree at the University of Kansas School of Medicine, practices at the Gillett Health Clinic in Olathe, Kansas, and is the host of The Gillett Health Podcast. His practice focuses on preventive, integrative, and precision medicine approaches, with expertise in hormone and metabolic optimization.In this wide-ranging discussion, we cover:Using genotyping and pharmacogenomics to guide personalized medicineAssessing the impact of environmental contaminants versus diet on metabolic healthThe lean mass hyper responder phenotype that some experience on ketogenic dietsPerspectives on non-nutritive sweeteners and emerging research on alluloseTailoring exercise plans as medicine for each patient’s needs and goalsOptimizing sleep, sunlight, and stress - key for shift workersThe importance of cultivating emotional wellness for overall healthDon't miss Dr. Gillett's talk at Metabolic Health Summit 2024! Register now before spots sell out at MetabolicHealthSummit.com.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

This week's episode of The Metabolic Link features an eye-opening discussion between Metabolic Health Summit organizer Victoria Field and prenatal nutrition expert Lily Nichols, RDN, CDE. Lily is the author of two bestselling books - Real Food for Pregnancy and Real Food for Gestational Diabetes. Her work focuses on evidence-based, critical analysis of conventional pregnancy nutrition recommendations.In this episode, we cover:Evaluating macronutrient needs in pregnancy, including research suggesting carbohydrate intake recommendations may be set too high, and protein intake targets too lowThe use of nutritional ketosis in pregnancyThe latest research on preventing gestational diabetes and preeclampsia through dietHow to eat for a healthy postpartum recovery - it's about way more than breastfeeding!The fascinating science of how prenatal nutrition impacts gene expression in babiesLily shares paradigm-shifting insights from her clinical experience and extensive research. Her balanced approach debunks outdated advice while offering practical solutions. Expect an illuminating conversation that will change how you think about nourishing yourself and your future baby!Don't miss Lily's talk at the Metabolic Health Summit 2024 in Clearwater Beach, Florida! Register now before spots sell out at metabolichealthsummit.com.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

In this week’s episode of The Metabolic Link, double board certified psychiatrist and obesity medicine physician, Dr. Shebani Sethi, takes us on a deep dive into the emerging field of metabolic psychiatry.Dr. Shebani Sethi is a psychiatrist and obesity medicine physician at Stanford University School of Medicine. She is the founding director of the Stanford Metabolic Psychiatry Clinic, where she researches dietary and pharmacological interventions to improve metabolic health and mental illness. Her background and expertise in integrating low carbohydrate nutrition with psychiatric care has created the foundation for Dr. Sethi to effectively treat patients based on the link between metabolism and brain function.In this episode filmed in May 2022, we cover:How Dr. Sethi implements metabolic therapy like ketogenic diets to improve psychiatric symptoms in patientsDetails on her clinical research, including a pilot study on ketogenic diets for schizophrenia and bipolar disorderUsing ketosis for 15+ years to treat conditions like depressionHopes for metabolic psychiatry concepts to spread and integrated care to become more accessibleFuture studies examining fMRI brain imaging on ketogenic dietsIf you’re interested in learning more about the body-brain connection and how metabolic dysfunction relates to mental illness, you won’t want to miss this episode!In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

This week’s episode of The Metabolic Link features an illuminating conversation between our host Dominic D’Agostino, PhD, and Dr. Abbi Hernandez, an assistant professor at the University of Alabama at Birmingham.Dr. Hernandez received her PhD from the University of Florida, where she studied age and diet related changes in neurological function and cognitive health. Her research has focused on investigating the potential of ketogenic diets and time-restricted feeding for preventing age-related cognitive decline. Recently, she has been exploring the gut-brain axis.In this episode, we cover:The importance of the hippocampus for learning, memory, and cognitionInnovative rodent behavioral tests used to identify age-related cognitive impairmentsMetabolic flexibility in the aging brain and the role of ketonesHow time-restricted feeding alters the gut microbiome and cognitive performanceFuture research directions on alternative brain fuels like lactateExploring the possibility of using probiotics to mimic the effects of ketosis on the brainDr. Hernandez will also be a speaker at Metabolic Health Summit 2024! Secure your spot here! Early bird pricing runs through October 1st and then it's gone for good!In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.