

How Allulose Aids Metabolism & Fructose Fuels Cancer | Journal Club | The Metabolic Link Ep. 30
Dec 19, 2023
Discover the metabolic wonders of allulose, a low-calorie sweetener that supports insulin sensitivity and aids weight management. The hosts highlight how allulose might revolutionize dietary approaches for diabetes and metabolic disorders. They dive into the alarming links between fructose and cancer progression, discussing how high fructose intake fuels tumors and triggers obesity-related risks. The conversation emphasizes dietary fructose restriction as a potential anti-cancer measure, all while underscoring the need for further research in these critical areas.
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Allulose: A Promising Sugar Substitute
- Allulose, a rare sugar found in nature, shares a similar chemical structure to sucrose but has a tenth of the calories.
- This makes allulose a promising sugar substitute with potential metabolic benefits.
Allulose, GLP-1, and the Blood-Brain Barrier
- Allulose stimulates GLP-1, a gut hormone, similar to some anti-obesity drugs.
- Unlike those drugs, allulose doesn't cross the blood-brain barrier, potentially reducing side effects.
D'Agostino's Allulose Experiment
- Dominic D'Agostino experimented with consuming 60g of allulose daily, equivalent to a high dose used in mice studies.
- He experienced no adverse effects when consuming allulose in RX Sugar bars, but pure allulose caused GI issues.