ICU Ed and Todd-Cast

Send us a Text Message (please include your email so we can respond!)Episode 27! In this episodes we sit down to talk all about the "when" to intubate a patient centered around acute poisoning in the NICO trial or "Effect of Noninvasive Airway Management of Comatose Patients With Acute Poisoning: A Randomized Clinical Trial" published by Freud et al in JAMA November 2023. We ended up talk a lot about that so we cut our old article a little bit short and discuss a couple of JAMA articles about definitive airways in out of hospital cardiac arrestNICO: https://pubmed.ncbi.nlm.nih.gov/38019968/PART: https://pubmed.ncbi.nlm.nih.gov/30167699/Prehospital advanced airway: https://pubmed.ncbi.nlm.nih.gov/23321764/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)This was easily our most requested article to discuss and for good reason - Eddie and Todd recently published the ACORN trial or "Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection" in JAMA October 2023. We recognize our bias as the first and last authors on the paper so we wanted to get some other smart people in the studio to balance us out so we partnered with Furf and Monty of PulmPEEPs for this episode. It is simul-dropping on their feed as well. Thank you to them for a great episode and the opportunity to talk about our trial!ACORN: https://pubmed.ncbi.nlm.nih.gov/37837651/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

In this podcast, they discuss the MINT trial related to restrictive transfusion strategies in heart attacks and an observational study on intracerebral hemorrhage in blood donors. They cover the implications for patient care, unique medical cases, and explore transfusion thresholds in critical care and oncology. The hosts compare different trials, delve into the complexities of interpreting trial results, and explore the risks of cerebral hemorrhages in transfusion recipients. They also touch on linguistics, career viability, and social media engagement.

Send us a Text Message (please include your email so we can respond!)Episode 24! Three trials about COVID were published with ESICM which we talk about all three here. COVID has been decreasing in prevalence in our ICU at least so we anchor our discussion around what we can learn from these trials about ARDS in general or what we can carry forward to future pandemics compared to our typical "Are we using this in our practice".Simvastatin: https://pubmed.ncbi.nlm.nih.gov/37888913/Vitamin C: https://pubmed.ncbi.nlm.nih.gov/37877585/Convalescent Plasma: https://pubmed.ncbi.nlm.nih.gov/37889107/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 23! We spend a little bit of time talking about our recent conference related travel and food experience but dive into our coverage of the trials that released with ESICM including "Inhaled Amikacin to Prevent Ventilator-Associated Pneumonia" by Ehrmann et al published in NEJM and "Landiolol and Organ Failure in Patients With Septic Shock" by Whitehouse et al in JAMA, both October 2023AMIKINHAL: https://pubmed.ncbi.nlm.nih.gov/37888914/STRESS-L: https://pubmed.ncbi.nlm.nih.gov/37877587/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 22! In this episode we talk about "Peripheral Administration of Norepinephrine: A Prospective Observational Study" published August 2023 by Yerke et al in CHEST. For our old article we talk about "Effect of midodrine versus placebo on time to vasopressor discontinuation in patients with persistent hypotension in the intensive care unit (MIDAS)" by Santer et al published October 2020 by Santer et al.No mailbag this time, we recorded this episode ahead of time to account for travel schedules.Peripheral Pressors: https://pubmed.ncbi.nlm.nih.gov/37611862/MIDAS: https://pubmed.ncbi.nlm.nih.gov/32885276/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Live show? Thank you so much to the organizers of the ACNP/PA Critical Care Bootcamp who invited us to do a live episode of the show! We talked about the AKIKI2 trial "Comparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury" by Gaudry et al in Lancet 2021.AKIKI2: https://pubmed.ncbi.nlm.nih.gov/33812488/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 21! In this episode we talk about "Extracorporeal Life Support in Infarct-Related Cardiogenic Shock" published August 2023 by Thiele et al in NEJM. Then we dive into our neglected mail bad to try to answer some listener questions.ECLS-SHOCK: https://pubmed.ncbi.nlm.nih.gov/37634145/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 20! In this episode we talk about "Effect of Selective Decontamination of the Digestive Tract on Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation" published October 2022 by the ANZICS group in JAMA. We have the first author and senior authors on the accompanying systematic review and meta-analysis, Naomi Hammond and Anthony Delany, all the way from Australia (!) on with us to talk to us about the trial.SuDDICU: https://pubmed.ncbi.nlm.nih.gov/36286097/Meta-analysis: https://pubmed.ncbi.nlm.nih.gov/36286098/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 19! In this episode we talk about "Oxygen-Saturation Targets for Critically Ill Adults Receiving Mechanical Ventilation" published November 2022 by Semler et al in the New England Journal of Medicine. We have the first author, Matt Semler, on with us to talk to us about the trial and his improv comedy claim to fame.PILOT: https://pubmed.ncbi.nlm.nih.gov/36278971/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!